Altered Glycosylation Sites of the δ Subunit of the Acetylcholine Receptor (AChR) Reduce αδ Association and Receptor Assembly

Primary structure of α-subunit precursor of Torpedo californica acetylcholine receptor deduced from cDNA sequence

1982 • 730 citations

How N-linked oligosaccharides affect glycoprotein folding in the endoplasmic reticulum.

1994 • 617 citations

Toward a structural basis for the function of nicotinic acetylcholine receptors and their cousins

1995 • 614 citations

Ligand-gated ion channels in the brain: The amino acid receptor superfamily

1990 • 397 citations

Complete mRNA coding sequence of the acetylcholine binding alpha-subunit of Torpedo marmorata acetylcholine receptor: a model for the transmembrane organization of the polypeptide chain.

1983 • 332 citations

Structure of nicotinic acetylcholine receptors

1993 • 234 citations

Assembly in vivo of mouse muscle acetylcholine receptor: Identification of an α subunit species that may be an assembly intermediate

1983 • 204 citations

Inhibition of glycosylation with tunicamycin blocks assembly of newly synthesized acetylcholine receptor subunits in muscle cells.

1982 • 193 citations

Glycobiology: “Towards Understanding the Function of Sugars”

1995 • 179 citations

Gamma- and delta-subunits regulate the affinity and the cooperativity of ligand binding to the acetylcholine receptor.

1991 • 163 citations

Isolation and characterization of a cDNA clone for the complete protein coding region of the delta subunit of the mouse acetylcholine receptor.

1984 • 155 citations

The N-terminal domains of acetylcholine receptor subunits contain recognition signals for the initial steps of receptor assembly

1992 • 149 citations

In vitro synthesis, glycosylation, and membrane insertion of the four subunits of Torpedo acetylcholine receptor.

1981 • 147 citations

Analysis of the site in CD4 that binds to the HIV envelope glycoprotein.

1990 • 132 citations

Mutational analysis of muscle nicotinic acetylcholine receptor subunit assembly.

1990 • 122 citations

Formation of the alpha-bungarotoxin binding site and assembly of the nicotinic acetylcholine receptor subunits occur in the endoplasmic reticulum.

1987 • 119 citations

Monoclonal antibodies to cytoplasmic domains of the acetylcholine receptor.

1983 • 118 citations

Assembly of the mammalian muscle acetylcholine receptor in transfected COS cells.

1991 • 116 citations

Native folding of an acetylcholine receptor alpha subunit expressed in the absence of other receptor subunits.

1988 • 114 citations

Association of muscle-specific kinase MuSK with the acetylcholine receptor in mammalian muscle

1997 • 110 citations

Alpha and beta subunits of the nicotinic acetylcholine receptor contain covalently bound lipid.

1984 • 106 citations

Assembly intermediates of the mouse muscle nicotinic acetylcholine receptor in stably transfected fibroblasts.

1990 • 102 citations

Intersubunit contacts governing assembly of the mammalian nicotinic acetylcholine receptor

1995 • 95 citations

Functional Interaction of Src Family Kinases with the Acetylcholine Receptor in C2 Myotubes

1996 • 94 citations

Extracellular domains mediating ɛ subunit interactions of muscle acetylcholine receptor

1991 • 94 citations

Properties of embryonic and adult muscle acetylcholine receptors transiently expressed in COS cells

1990 • 90 citations

Expression of fusion proteins of the nicotinic acetylcholine receptor from mammalian muscle identifies the membrane-spanning regions in the alpha and delta subunits.

1992 • 88 citations

The transmembrane topology of the amino terminus of the alpha subunit of the nicotinic acetylcholine receptor

1991 • 84 citations

Nucleotide sequence of the mouse nicotinic acetylcholine receptor α subunit

1986 • 82 citations

A universal oligonucleotide probe for acetylcholine receptor genes. Selection and sequencing of cDNA clones for the mouse muscle beta subunit.

1986 • 81 citations

Carbohydrate structures of acetylcholine receptor from Torpedo californica and distribution of oligosaccharides among the subunits

1986 • 80 citations

Acetylcholine receptor subunits transit a precursor pool before acquiring alpha-bungarotoxin binding activity.

1981 • 76 citations

Identification of two amino acid residues in the ϵ subunit that promote mammalian muscle acetylcholine receptor assembly in COS cells

1991 • 75 citations

Assembly of Torpedo acetylcholine receptors in Xenopus oocytes.

1991 • 71 citations

N-Glycosylation at the conserved sites ensures the expression of properly folded functional ACh receptors

1997 • 70 citations

Adenovirus-mediated transfection of cultured cells.

1994 • 66 citations

Acetylcholine receptor in a C2 muscle cell variant is retained in the endoplasmic reticulum.

1989 • 55 citations

Characterization of acetylcholine receptor subunits in developing and in denervated mammalian muscle.

1988 • 54 citations

Analysis of the conserved glycosylation site in the nicotinic acetylcholine receptor: potential roles in complex assembly

1995 • 48 citations

Formation of the Nicotinic Acetylcholine Receptor Binding Sites

1998 • 46 citations

Assembly of the Nicotinic Acetylcholine Receptor

1996 • 38 citations

Anionic Residue in the α-Subunit of the Nicotinic Acetylcholine Receptor Contributing to Subunit Assembly and Ligand Binding

1996 • 32 citations

Recognition domains in assembly of oligomeric membrane proteins

1992 • 26 citations

Subunit folding and alpha delta heterodimer formation in the assembly of the nicotinic acetylcholine receptor. Comparison of the mouse and human alpha subunits

1992 • 23 citations