Specificity of mutagenesis by 4-aminobiphenyl: mutations at G residues in bacteriophage M13 DNA and G-->C transversions at a unique dG(8-ABP) lesion in single-stranded DNA

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

DNA Repair and Mutagenesis

2006 • 4,725 citations

High efficiency transformation of E.coli by high voltage electroporation

1988 • 2,789 citations

Identification of p53 Gene Mutations in Bladder Cancers and Urine Samples

1991 • 891 citations

Mechanistic studies of ionizing radiation and oxidative mutagenesis: genetic effects of a single 8-hydroxyguanine (7-hydro-8-oxoguanine) residue inserted at a unique site in a viral genome

1990 • 687 citations

In vivo mutagenesis by O6-methylguanine built into a unique site in a viral genome.

1984 • 437 citations

Mutational specificity of depurination.

1984 • 361 citations

Slow Repair of Pyrimidine Dimers at p53 Mutation Hotspots in Skin Cancer

1994 • 301 citations

Frequent association of p53 gene mutation in Invasive bladder cancer

1992 • 265 citations

Hemoglobin adducts of 4-aminobiphenyl in smokers and nonsmokers.

1987 • 259 citations

Genetic effects of thymine glycol: site-specific mutagenesis and molecular modeling studies.

1989 • 204 citations

Depurination causes mutations in SOS-induced cells.

1981 • 186 citations

Carcinogen-induced mutation spectrum in wild-type, uvrA and umuC strains of Escherichia coli

1984 • 183 citations

Arylamine-DNA adducts in vitro and in vivo: their role in bacterial mutagenesis and urinary bladder carcinogenesis

1983 • 180 citations

Distinct pattern of p53 mutations in bladder cancer: relationship to tobacco usage.

1993 • 170 citations

Mutational properties of the primary aflatoxin B1-DNA adduct.

1996 • 164 citations

DNA binding and mutation spectra of the carcinogen N-2-aminofluorene in Escherichia coli

1985 • 146 citations

Single adduct mutagenesis: strong effect of the position of a single acetylaminofluorene adduct within a mutation hot spot.

1989 • 141 citations

Influence of cigarette smoking and schistosomiasis on p53 gene mutation in urothelial cancer.

1993 • 115 citations

Mutagenicity and genotoxicity of the major DNA adduct of the antitumor drug cis-diamminedichloroplatinum(II)

1993 • 97 citations

Analysis of 4-aminobiphenyl-DNA adducts in human urinary bladder and lung by alkaline hydrolysis and negative ion gas chromatography-mass spectrometry.

1994 • 82 citations

Estimation of apurinic/apyrimidinic sites and phosphotriesters in deoxyribonucleic acid treated with electrophilic carcinogens and mutagens

1980 • 81 citations

High Frequency of Chromosome 9p Allelic Loss and CDKN2 Tumor Suppressor Gene Alterations in Squamous Cell Carcinoma of the Bladder

1995 • 74 citations

Detection and characterization of carcinogen—DNA adducts in exfoliated urothelial cells from 4-aminobiphenyl-treated dogs by ³²P-postlabelling and subsequent thin-layer and high-pressure liquid chromatography

1990 • 71 citations

NMR structural studies of a 15-mer DNA sequence from a ras protooncogene, modified at the first base of codon 61 with the carcinogen 4-aminobiphenyl

1992 • 60 citations

Complex frameshift mutations mediated by plasmid pKM101: mutational mechanisms deduced from 4-aminobiphenyl-induced mutation spectra in Salmonella.

1994 • 59 citations

Construction and characterization of extrachromosomal probes for mutagenesis by carcinogens: site-specific incorporation of O6-methylguanine into viral and plasmid genomes.

1984 • 57 citations

Mutations induced by aromatic amine DNA adducts in pBR322

1994 • 55 citations

H- AND K- ras MUTATIONAL PROFILES IN CHEMICALLY INDUCED LIVER TUMORS FROM B6C3F1 AND CD-1 MICE

1996 • 44 citations

Specificity of mutagenesis by 4-aminobiphenyl. A possible role for N-(deoxyadenosin-8-yl)-4-aminobiphenyl as a premutational lesion.

1988 • 38 citations

Synthesis of O‐Acetyl‐N (4‐biphenylyl)hydroxylamine (“NAcetoxy‐4‐aminobiphenyl”), an Ultimate Metabolite of Carcinogenic 4‐Aminobiphenyl, and Its Reaction with Deoxyguanosine

1989 • 35 citations

Effects of ortho-methyl substituents on the mutagenicity of aminobiphenyls and aminonaphthalenes

1981 • 32 citations

Tetrahedral intermediates formed by nitrogen and oxygen attack of aromatic hydroxylamines on acetyl cyanide

1987 • 31 citations

A probe for the mutagenic activity of the carcinogen 4-aminobiphenyl: synthesis and characterization of an M13mp10 genome containing the major carcinogen-DNA adduct at a unique site

1987 • 29 citations

Assessment of exposure and susceptibility to aromatic amine carcinogens.

1988 • 27 citations

Influence of the carcinogen 4-aminobiphenyl on DNA conformation

1985 • 24 citations

Comparison of mutagenesis induced in single- and double-stranded M13 viral DNA by treatment with N-hydroxy-2-aminofluorene

1988 • 21 citations

Comparative survival of aminobiphenyl- and aminofluorene- substituted plasmid DNA in Escherichia coli Uvr endonuclease deficient strains

1990 • 17 citations

Induction of mutations by N-acetoxy-acetyl-2-aminofluorene modified M13 viral DNA

1991 • 16 citations

Major and Minor Groove Conformations of DNA Trimers Modified on Guanine or Adenine by 4-Aminobiphenyl: Adenine Adducts Favor the Minor Groove

1995 • 9 citations

The action of 4-hydroxyaminobiphenyl in Escherichia coli: cytotoxic and mutagenic effects in DNA repair deficient strains

1993 • 4 citations

Modification of plasmid and bacteriophage DNA by aromatic amines: effects on survival, template activity, and mutagenicity.

1994 • 3 citations