Eicosapentaenoic acid, but not docosahexaenoic acid, increases mitochondrial fatty acid oxidation and upregulates 2,4‐dienoyl‐CoA reductase gene expression in rats

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Molecular cloning: A laboratory manual

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

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A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES

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Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

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Chapter 4 Preparation of Isolated Rat Liver Cells

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A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

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Regulation of Hepatic Fatty Acid Oxidation and Ketone Body Production

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1989 • 1,152 citations

Reduction of Plasma Lipids, Lipoproteins, and Apoproteins by Dietary Fish Oils in Patients with Hypertriglyceridemia

1985 • 862 citations

The metabolism of 7,10,13,16,19-docosapentaenoic acid to 4,7,10,13,16,19-docosahexaenoic acid in rat liver is independent of a 4-desaturase.

1991 • 660 citations

Enzymes of Glycerolipid Synthesis in Eukaryotes

1980 • 626 citations

Fish oil consumption and decreased risk of cardiovascular disease: a comparison of findings from animal and human feeding trials

1986 • 509 citations

Mitochondrial and peroxisomal fatty acid oxidation in liver homogenates and isolated hepatocytes from control and clofibrate-treated rats.

1979 • 436 citations

Effect of oral administration of highly purified eicosapentaenoic acid on platelet function, blood viscosity and red cell deformability in healthy human subjects

1983 • 392 citations

Differences in plasma cholesteryl ester transfer activity in sixteen vertebrate species

1982 • 370 citations

Human absorption of fish oil fatty acids as triacylglycerols, free acids, or ethyl esters

1988 • 347 citations

Lignoceric acid is oxidized in the peroxisome: implications for the Zellweger cerebro-hepato-renal syndrome and adrenoleukodystrophy.

1984 • 344 citations

Dietary polyunsaturated fats of the W-6 and W-3 series reduce postprandial lipoprotein levels. Chronic and acute effects of fat saturation on postprandial lipoprotein metabolism.

1988 • 338 citations

Reduction of postprandial triglyceridemia in humans by dietary n-3 fatty acids

1988 • 325 citations

Active and inactive forms of 3-hydroxy-3-methylglutaryl coenzyme A reductase in the liver of the rat. Comparison with the rate of cholesterol synthesis in different physiological states.

1979 • 309 citations

The adaptive effects of dietary fish and safflower oil on lipid and lipoprotein metabolism in perfused rat liver

1984 • 305 citations

Eicosapentaenoic acid reduces hepatic synthesis and secretion of triacylglycerol by decreasing the activity of acyl-coenzyme A:1,2-diacylglycerol acyltransferase

1988 • 289 citations

Triglyceride-lowering effect of marine polyunsaturates in patients with hypertriglyceridemia.

1985 • 216 citations

Differential mobilization of white adipose tissue fatty acids according to chain length, unsaturation, and positional isomerism

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Effects of N-3 Fatty Acids on Lipid Metabolism

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Docosahexaenoic acid shows no triglyceride-lowering effects but increases the peroxisomal fatty acid oxidation in liver of rats.

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Regulation of Fat Metabolism in the Liver

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Paradoxical elevation of LDL apoprotein B levels in hypertriglyceridaemic patients and normal subjects ingesting fish oil

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Acyl-CoA oxidase from Candida tropicalis

1979 • 154 citations

Absorption of the n − 3 eicosapentaenoic and docosahexaenoic acids as ethyl esters and triglycerides by humans

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Lipoprotein Lipases, Lipoproteins and Tissue Lipids in Rats Fed Fish Oil or Coconut Oil

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Reduced triglyceride formation from long-chain polyenoic fatty acids in rat hepatocytes

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Degradation of Unsaturated Fatty Acids. Identification of Intermediates in the Degradation of cis-4-Decenoyl-CoA by Extracts of Beef-Liver Mitochondria

1978 • 135 citations

Absorption of eicosapentaenoic acid and docosahexaenoic acid from fish oil triacylglycerols or fish oil ethyl esters co-ingested with a high-fat meal

1988 • 135 citations

The acylation of glycerophosphate in rat liver A new assay procedure for glycerophosphate acylation, studies on its subcellular and submitochondrial localization and determination of the reaction products

1970 • 133 citations

Fish oil attenuates the cholesterol induced rise in lipoprotein cholesterol

1986 • 130 citations

Assay of short-chain acyl coenzyme a intermediates in tissue extracts by high-pressure liquid chromatography

1981 • 129 citations

Absorption and transport of fat in mammals with emphasis on n−3 polyunsaturated fatty acids

1988 • 127 citations

Eicosapentaenoic acid inhibits the secretion of triacylglycerol and of apoprotein B and the binding of LDL in Hep G2 cells

1987 • 124 citations

Differential Effects of Fish Oil, Safflower Oil and Palm Oil on Fatty Acid Oxidation and Glycerolipid Synthesis in Rat Liver

1991 • 119 citations

A diet rich in (n−3) fatty acids increases peroxisomal β-oxidation activity and lowers plasma triacylglycerols without inhibiting glutathione-dependent detoxication activities in the rat liver

1987 • 119 citations

Fish oil fatty acids impair VLDL assembly and/or secretion by cultured rat hepatocytes.

1990 • 116 citations

The hypotriglyceridemic effect of eicosapentaenoic acid in rats is reflected in increased mitochondrial fatty acid oxidation followed by diminished lipogenesis

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Expression of oncogenes in thyroid tumours: coexpression of c-erbB2/neu and c-erbB

1988 • 115 citations

The effect of (−)carnitine on the metabolism of palmitate in liver cells isolated from fasted and refed rats

1976 • 113 citations

Effect of Dietary Cholesterol and/or ω3 Fatty Acids on Lipid Composition and Δ5-Desaturase Activity of Rat Liver Microsomes

1988 • 112 citations

Differential effects of dietary eicosapentaenoic and docosahexaenoic fatty acids on lowering of triglyceride and cholesterol levels in the serum of rats on hypercholesterolemic diet.

1984 • 110 citations

Pulmonary surfactant synthesis. A highly active microsomal phosphatidate phosphohydrolase in the lung.

1978 • 108 citations

α-Linolenic, Eicosapentaenoic and Docosahexaenoic Acids Affect Lipid Metabolism Differently in Rats

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Eicosapentaenoic acid inhibits cholesterol esterification in cultured parenchymal cells and isolated microsomes from rat liver.

1988 • 98 citations

Evidence for peroxisomal retroconversion of adrenic acid (22:4(n-6)) and docosahexaenoic acids (22:6(n-3)) in isolated liver cells

1986 • 97 citations

Evidence for mechanisms of the hypotriglyceridemic effect of n − 3 polyunsaturated fatty acids

1992 • 97 citations

Effect of eicosapentaenoic acid on the platelet aggregation and composition of fatty acid in man A double blind study

1983 • 97 citations

The enteral bioavailability of eicosapentaenoic acid and docosahexaenoic acid is as good from ethyl esters as from glyceryl esters in spite of lower hydrolytic rates by pancreatic lipase in vitro

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Dietary fish oil increases conversion of very low density lipoprotein apoprotein B to low density lipoprotein.

1989 • 95 citations

Effects of eicosapentaenoic and docosahexaenoic acids on apoprotein B mRNA and secretion of very low density lipoprotein in HepG2 cells.

1989 • 92 citations

[1] Acetyl-CoA carboxylase from rat liver

1981 • 91 citations

Changes of plasma lipids and long-chain n−3 and n−6 fatty acids in plasma, liver, heart and kidney phospholipids of rats fed variable levels of fish oil with or without cholesterol supplementation

1986 • 82 citations

Comparative effects of dietary fish oil and carbohydrate on plasma lipids and hepatic activities of phosphatidate phosphohydrolase, diacylglycerol acyltransferase and neutral lipase activities in the rat

1987 • 81 citations

Distinct long chain and very long chain fatty acyl CoA synthetases in rat liver peroxisomes and microsomes

1988 • 77 citations

On the effect of peroxisomal β‐oxidation and carnitine palmitoyltransferase activity by eicosapentaenoic acid in liver and heart from rats

1990 • 74 citations

Inhibition of apolipoprotein secretion and phosphatidate phosphohydrolase activity by eicosapentaenoic and docosahexaenoic acids in the perfused rat liver

1988 • 73 citations

Lipid digestion in cod (gadus morhua)

1987 • 71 citations

The effects of n-3 fatty acids on plasma lipids and lipoproteins and other cardiovascular risk factors in patients with hyperlipidemia

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Effect of fish oil on atherosclerosis and lipoprotein metabolism

1990 • 69 citations

Effect of dietary fish oil on blood levels of free fatty acids, ketone bodies and triacylglycerol in humans

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Rapid method for the separation and detection of tissue short-chain coenzyme A esters by reversed-phase high-performance liquid chromatography

1995 • 69 citations

Alkylthioacetic acids (3-thia fatty acids) as non-beta-oxidizable fatty acid analogues: a new group of hypolipidemic drugs. III. Dissociation of cholesterol- and triglyceride-lowering effects and the induction of peroxisomal beta-oxidation.

1989 • 68 citations

Eicosapentaenoic acid ethyl ester as an antithrombotic agent: comparison to an extract of fish oil

1991 • 66 citations

Reduction in microalbuminuria in diabetics by eicosapentaenoic acid ethyl ester

1990 • 58 citations

Effect of n−3 fatty acids on the key enzymes involved in cholesterol and triglyceride turnover in rat liver

1991 • 57 citations

A selective decrease in mitochondrial glycerol phosphate acyltransferase activity in livers from streptozotocin‐diabetic rats

1977 • 57 citations

The differential effect of eicosapentaenoic acid and oleic acid on lipid synthesis and VLDL secretion in rabbit hepatocytes

1990 • 54 citations

Prolonged inhibition of platelet aggregation after n-3 fatty acid ethyl ester ingestion by healthy volunteers

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Determination of Free Fatty Acids: A Comparative Study of the Enzymatic Versus the Gas Chromatographic and the Colorimetric Method

1983 • 53 citations

Regulation of fatty acid oxidation and triglyceride and phospholipid metabolism by hypolipidemic sulfur-substituted fatty acid analogues

1990 • 52 citations

Rapid stimulation of liver palmitoyl-CoA synthetase, carnitine palmitoyltransferase and glycerophosphate acyltransferase compared to peroxisomal β-oxidation and palmitoyl-CoA hydrolase in rats fed high-fat diets

1988 • 52 citations

Dietary effect of .OMEGA.-3 type polyunsaturated fatty acids on serum and liver lipid levels in rats.

1983 • 51 citations

Trypanosoma brucei: A quick method for separating blood-stream trypomastigotes from infected blood by differential osmotic lysis

1982 • 50 citations

Comparison of the activities of some peroxisomal and extraperoxisomal lipid-metabolizing enzymes in liver and extrahepatic tissues of the rat

1985 • 49 citations

Effect of a high fat/cholesterol diet with or without eicosapentaenoic acid on plasma lipids, lipoproteins and lipid transfer protein activity in the marmoset

1990 • 48 citations

Lumenal hydrolysis of menhaden and rapeseed oils and their fatty acid methyl and ethyl esters in the rat

1989 • 44 citations

Cellular oxidation of lignoceric acid is regulated by the subcellular localization of lignoceroyl-CoA ligases.

1990 • 44 citations

Impact of cytochrome P450 system on lipoprotein metabolism. Effect of abnormal fatty acids (3-thia fatty acids)

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EFFECTS OF CERTAIN PURE LONG CHAIN POLYUNSATURATED FATTY ACID ESTERS ON THE BLOOD LIPIDS OF MAN

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Lipoprotein lipases, lipoprotein density gradient profile and LDL receptor activity in miniature pigs fed fish oil and corn oil

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Reduction in triacylglycerol levels by fish oil correlates with free fatty acid levels inad libitum fed rats

1992 • 34 citations

Feeding pure docosahexaenoate or arachidonate decreases plasma triacylglycerol secretion in rats

1989 • 33 citations

Effects of Omega-3 Fatty Acids in Hypertriglyceridemic States

1988 • 32 citations

Apparent inhibition of hepatic triacylglycerol secretion, independent of synthesis, in high-fat fish oil-fed rats: role for insulin

1991 • 32 citations

Metabolism of n−3 polyunsaturated fatty acids by the isolated perfused rat liver

1991 • 25 citations

Very long chain fatty acid β-oxidation by subcellular fractions of normal and Zellweger syndrome skin fibroblasts

1987 • 24 citations

Time-course of changes in plasma lipids in diabetic rats fed diets high in fish or safflower oils

1986 • 23 citations

Effect of oral administration of highly purified eicosapentaenoic acid and docosahexaenoic acid on platelet function and serum lipids in hyperlipidemic patients.

1989 • 19 citations

(Biochim. Biophys. Acta, 879:022-027)Changes of plasma lipids and long chain n-3 and n-6 fatty acids in plasma, liver, heart and kidney phospholipids of rats fed variable levels of fish oil with or without cholesterol supplementation

1986 • 12 citations

Effect of 4,7,10,13,16,19‐docosahexaenoic acid on triglyceride accumulation and secretion in rat hepatocytes in culture

1991 • 11 citations

Concentration‐dependent effects of eicosapentaenoic acid on very low density lipoprotein secretion by the isolated perfused rat liver

1993 • 8 citations

Absorption and Transport of Fat

1971 • 6 citations