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Immunoglobulins D and M mediate signals that are qualitatively different in B cells with an immature phenotype.

Data up to Jan 2025

Published1988
Citations78
References27

Total Citations Per Year

Abstract

References (27)

Molecular Mechanisms of Transmembrane Signaling in B Lymphocytes

1987 • 279 citations

Differences in susceptibility of mature and immature mouse B lymphocytes to anti-immunoglobulin-induced immunoglobulin suppression in vitro. Possible implications for B-cell tolerance to self.

1975 • 228 citations

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1975 • 200 citations

Ontogeny of Ia and IgD on IgM-bearing B lymphocytes in mice.

1977 • 129 citations

Transcriptional regulation of the mu-delta heavy chain locus in normal murine B lymphocytes.

1984 • 112 citations

Cross-linking of surface immunoglobulin on B lymphocytes induces both intracellular Ca2+ release and Ca2+ influx: Analysis with indo-1

1986 • 112 citations

Functional differences between immunoglobulins M and D expressed on the surface of an immature B-cell line.

1988 • 106 citations

Modification of B Lymphocyte Differentiation by Anti-Immunoglobulins

1974 • 106 citations

Role of IgD in the immune response and tolerance. I. Anti-delta pretreatment facilitates tolerance induction in adult B cells in vitro.

1977 • 93 citations

B-cell tolerance. III. Effect of papain-mediated cleavage of cell surface IgD on tolerance susceptibility of murine B cells.

1977 • 84 citations

Murine Models of Tolerance Induction in Developing and Mature B Cells

1979 • 77 citations

B-cell tolerance. IV. Differential role of surface IgM and IgD in determining tolerance susceptibility of murine B cells

1977 • 76 citations

Membrane IgM, IgD, and IgG act as signal transmission molecules in a series of B lymphomas.

1986 • 75 citations

Cross-reactive idiotypes and common antigen binding specificities expressed by a series of murine B-cell lymphomas: etiological implications.

1985 • 73 citations

In vitro and in vivo B lymphocyte-activating properties of monoclonal anti-delta antibodies. I. Determinants of B lymphocyte-activating properties.

1986 • 67 citations

Up-regulation of c-fos expression is a component of the mIg signal transduction mechanism but is not indicative of competence for proliferation.

1988 • 62 citations

The effect of anti-immunoglobulin antibodies on the in vitro proliferation and differentiation of normal and neoplastic murineB cells.

1980 • 52 citations

Lymphoma models for B cell activation and tolerance IV. Growth inhibition by anti‐Ig of CH31 and CH33 B lymphoma cells

1986 • 51 citations

Role of phosphoinositide-derived second messengers in mediating anti-IgM-induced growth arrest of WEHI-231 B lymphoma cells.

1988 • 46 citations

mIgM:mIgD ratios on B cells: mean mIgD expression exceeds mIgM by 10-fold on most splenic B cells.

1984 • 45 citations

Induction of murine B cell proliferation by insolubilized anti-immunoglobulins.

1980 • 43 citations

B‐CELL SUBPOPULATIONS IDENTIFIABLE BY TWO‐COLOR FLUORESCENCE ANALYSIS USING A DUAL‐LASER FACS*

1982 • 37 citations

Cell Fractionation Methods and the Target Cells for Clonal Abortion of B Lymphocytes

1979 • 36 citations

Assessment of antigen-specific receptor function of surface immunoglobulin M and D with identical hapten specificity.

1987 • 19 citations

Lymphoma models for B cell activation and tolerance. V. Anti-Ig mediated growth inhibition is reversed by phorbol myristate acetate but does not involve changes in cytosolic free calcium.

1987 • 19 citations

Immunoglobulin D : structure and function

1982 • 16 citations

Immunoglobulin D: structure and function.

1982 • 14 citations

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Immunoglobulins D and M mediate signals that are qualitatively different in B cells with… (1988) – Proceedings of the National Academy of Sciences | Metascience Observatory Explorer