Modification of B Lymphocyte Differentiation by Anti-Immunoglobulins

The clonal selection theory of acquired immunity

1959 • 2,008 citations

The clonal selection theory of acquired immunity

1959 • 1,576 citations

A POPULATION OF LYMPHOCYTES BEARING A MEMBRANE RECEPTOR FOR ANTIGEN-ANTIBODY-COMPLEMENT COMPLEXES

1970 • 1,144 citations

INTERACTION OF AGGREGATED γ-GLOBULIN WITH B LYMPHOCYTES

1972 • 686 citations

IMMUNOGLOBULINS ON THE SURFACE OF LYMPHOCYTES

1971 • 665 citations

Cell Selection by Antigen in the Immune Response

1969 • 594 citations

Progress in immunology

1968 • 577 citations

IMMUNOGLOBULIN SPOTS ON THE SURFACE OF RABBIT LYMPHOCYTES

1970 • 553 citations

Two distinct populations of peripheral lymphocytes in mice distinguishable by immunofluorescence.

1970 • 479 citations

A RECEPTOR FOR ANTIBODY ON B LYMPHOCYTES

1972 • 469 citations

CELLULAR LOCALIZATION OF IMMUNOGLOBULINS WITH DIFFERENT ALLOTYPIC SPECIFICITIES IN RABBIT LYMPHOID TISSUES

1965 • 444 citations

Croonian lecture.—On immunity with special reference to cell life

1900 • 427 citations

DEMONSTRATION OF MOUSE ISOANTIGENS AT THE CELLULAR LEVEL BY THE FLUORESCENT ANTIBODY TECHNIQUE

1961 • 367 citations

COMPETITION OF 19S AND 7S ANTIGEN RECEPTORS IN THE REGULATION OF THE PRIMARY IMMUNE RESPONSE

1968 • 328 citations

SINGLE CELL STUDIES ON 19S ANTIBODY PRODUCTION

1964 • 317 citations

SURFACE ALLOANTIGENS OF PLASMA CELLS

1970 • 281 citations

ELEMENTAL DIETS

1975 • 277 citations

CARRIER FUNCTION IN ANTI-HAPTEN IMMUNE RESPONSES

1970 • 265 citations

CELL INTERACTIONS IN THE IMMUNE RESPONSE IN VITRO

1972 • 253 citations

SUPPRESSION OF IMMUNOGLOBULIN CLASS SYNTHESIS IN MICE

1972 • 240 citations

Suppression of Immunoglobulin G Synthesis as a Result of Antibody-Mediated Suppression of Immunoglobulin M Synthesis in Chickens

1970 • 235 citations

RABBIT LYMPHOID CELLS DIFFERENTIATED WITH RESPECT TO α-, γ-, AND µ- HEAVY POLYPEPTIDE CHAINS AND TO ALLOTYPIC MARKERS A<scp>A</scp>1 AND A<scp>A</scp>2

1966 • 212 citations

IMMUNOGLOBULINS AS CELL RECEPTORS*

1971 • 209 citations

Development and distribution of immunoglobulin-containing cells in the chicken. An immunofluorescent analysis using purified antibodies to mu, gamma and light chains.

1971 • 206 citations

QUANTITATIVE FEATURES OF A SANDWICH RADIOIMMUNOLABELING TECHNIQUE FOR LYMPHOCYTE SURFACE RECEPTORS

1972 • 204 citations

Development and Function of the Immunoglobulin Producing System

1969 • 202 citations

Thymus Dependence of Antibody Response: Variation with Dose of Antigen and Class of Antibody

1968 • 195 citations

STUDIES ON THE REGULATION OF AVIDITY AT THE LEVEL OF THE SINGLE ANTIBODY-FORMING CELL

1970 • 185 citations

Evidence for Control of Synthesis of the Variable Regions of the Heavy Chains of Immunoglobulins G and M by the Same Gene

1970 • 182 citations

MOUSE THYMUS-INDEPENDENT AND THYMUS-DERIVED LYMPHOID CELLS

1972 • 164 citations

Development and Distribution of Immunoglobulin-Containing Cells in the Chicken

1971 • 157 citations

Circulating B-cells in patients with immunodeficiency.

1972 • 150 citations

Mouse Specific Bone Marrow-derived Lymphocyte Antigen as a Marker for Thymus-independent Lymphocytes

1971 • 143 citations

Blocking of the Lymphocyte Antigen Receptor Site with Anti-immunoglobulin Sera in vitro

1970 • 129 citations

Microenvironmental Aspects of Immunity

1973 • 126 citations

CELL SURFACE IMMUNOGLOBULIN

1972 • 123 citations

Restriction of Surface Immunoglobulin Determinants to Lymphocytes of the Plasma Cell Line

1971 • 122 citations

RECEPTORS ON IMMUNOCOMPETENT CELLS

1971 • 118 citations

RECEPTORS ON IMMUNOCOMPETENT CELLS

1972 • 118 citations

IMMUNE RESPONSES IN VITRO

1972 • 111 citations

IMMUNOGLOBULIN DETERMINANTS ON THE SURFACE OF HUMAN LYMPHOCYTES

1969 • 98 citations

DEMONSTRATION OF HEAVY AND LIGHT CHAIN ANTIGENIC DETERMINANTS ON THE CELL-BOUND RECEPTOR FOR ANTIGEN

1970 • 91 citations

Haptenated bacteriophage in the assay of antibody quantity and affinity: Maturation of an immune response

1970 • 90 citations

SERUM IMMUNOGLOBULINS AND ANTIBODIES IN CONGENITALLY ATHYMIC (NUDE) MICE

1972 • 87 citations

T Cells Can Bind Antigen via Cytophilic IgM Antibody Made by B Cells

1973 • 85 citations

Immunoglobulin A: Site and Sequence of Expression in Developing Chicks

1973 • 82 citations

Immune globulin production by the bursa of Fabricius of young chickens.

1968 • 82 citations

IMMUNOSUPPRESSION OF MICE INJECTED WITH HETEROLOGOUS ANTI-IMMUNOGLOBULIN HEAVY CHAIN ANTISERA

1972 • 74 citations

Affinity of IgM and IgG antibodies

1970 • 71 citations

IMMUNE RESPONSES IN VITRO

1972 • 69 citations

Regulation of antibody response in vitro. IV. Heavy chain antigenic determinants on hapten-specific memory cells.

1972 • 68 citations

The immunoglobulins of mice. VI. Response to immunization.

1965 • 64 citations

The identity of light chains of monoclonal IgG and monoclonal IgM in one patient

1969 • 61 citations

Immunoglobulin Determinants on Mouse Lymphocytes

1971 • 61 citations

Affinity of T and B lymphocyte receptors for hapten determinants

1973 • 59 citations

Survival and function of bursa-derived cells in bursectomized chickens

1973 • 55 citations

Immunosuppression in Mice Injected with Heterologous Anti-Immunoglobulin Antisera

1972 • 54 citations

Immunoglobulin Determinants on the Surface of Antigen Binding T- and B-Lymphocytes in Mice

1971 • 54 citations

DETERMINATION OF ANTIBODY CLASS IN A SYSTEM OF COOPERATING ANTIGENIC DETERMINANTS

1970 • 48 citations

Quantitative Studies on the Regulation of Expression of Genes for Immunoglobulin Allotypes in Heterozygous Rabbits

1967 • 46 citations

Studies on antibody affinity in mice

1973 • 44 citations

PRODUCTION OF A RUNTING SYNDROME AND SELECTIVE γA DEFICIENCY IN MICE BY THE ADMINISTRATION OF ANTI-HEAVY CHAIN ANTISERA

1973 • 43 citations

DELETION OF b5 IMMUNOGLOBULIN-BEARING LYMPHOCYTES IN ALLOTYPE-SUPPRESSED RABBITS

1973 • 40 citations

Differentiation of B Lymphocytes from Stem Cell Precursors

1973 • 39 citations

Antibody-binding characteristics at the cellular level. I. Comparative maturation of hapten-specific IgM and IgG plaque-forming cell populations.

1973 • 38 citations

Immunoglobulin Determinants on Lymphocytes of Adult, Neonatal and Foetal Pigs

1972 • 33 citations

The Immune Capacity of Lymphocytes after Cross-Linking of Surface Immunoglobulin Receptors by Antibody

1972 • 32 citations

Inhibition by anti- chain sera of the cellular transfer of antibody and immunoglobulin synthesis in mice.

1972 • 31 citations

The Immunoglobulins of Mice

1965 • 29 citations

Induction of Temporary IgA Deficiency in Mice Injected with Heterologous Anti-Immunoglobulin Heavy Chain Antisera

1972 • 27 citations

Regulation of antibody response in vitro. Suppression of secondary response by anti-immunoglobulin heavy chains.

1971 • 27 citations

Antibody-Binding Characteristics at the Cellular Level

1973 • 25 citations

Regulation of antibody response in vitro. II. Formation of rabbit reaginic antibody.

1972 • 24 citations

Surface Immunoglobulins on Lymphoid Cells

1972 • 23 citations

Inhibition by Anti-µ Chain Sera of the Cellular Transfer of Antibody and Immunoglobulin Synthesis in Mice

1972 • 22 citations

Immunoglobulin classes of antibody-forming cells in mice. II. Class restriction of plaque-forming cells demonstrated by replica plating.

1970 • 22 citations

Regulation of Antibody Response in Vitro

1971 • 21 citations

Effect of Anti-immunoglobulin Antisera on Homograft Rejection in Mice

1972 • 21 citations

Immunological Tolerance

1969 • 21 citations

Replica analysis of the class of antibodies produced by single cells.

1970 • 19 citations

Regulation of Antibody Response in Vitro

1972 • 19 citations

Allotypic suppression of adult mouse spleen cells: Cell differentiation, class restriction and allotypic exclusion

1972 • 18 citations

Antibody-binding characteristics at the cellular level. II. Presence of cells secreting high affinity IgG antibody at the onset of the immune response.

1973 • 17 citations

Regulation of Antibody Response in Vitro

1972 • 16 citations

Immunoglobulin Classes of Antibody-Forming Cells in Mice

1970 • 15 citations

Antibody-Binding Characteristics at the Cellular Level

1973 • 14 citations

Population Stability (Reply)

1972 • 12 citations

Early Appearance of Antigen-Binding Cells to Two Different Antigens during Fetal Lymphoid Development

1973 • 6 citations