Interaction of glucocorticosteroid receptor and wild-type or mutated 90-kDa heat shock protein coexpressed in baculovirus-infected Sf9 cells.

THE HEAT-SHOCK PROTEINS

1988 • 5,214 citations

Protein folding in the cell

1992 • 4,138 citations

Functional domains of the human glucocorticoid receptor

1986 • 933 citations

Reduced levels of hsp90 compromise steroid receptor action in vivo

1990 • 794 citations

hsp82 is an essential protein that is required in higher concentrations for growth of cells at higher temperatures.

1989 • 624 citations

The common 90-kd protein component of non-transformed ‘8S’ steroid receptors is a heat-shock protein.

1985 • 527 citations

Hsp90 chaperones protein folding in vitro

1992 • 514 citations

Steroid receptors and their associated proteins.

1993 • 513 citations

Common non-hormone binding component in non-transformed chick oviduct receptors of four steroid hormones

1984 • 442 citations

Evidence That the 90-kDa Heat Shock Protein Is Necessary for the Steroid Binding Conformation of the L Cell Glucocorticoid Receptor

1989 • 394 citations

The specific interaction of the Rous sarcoma virus transforming protein, pp60src, with two cellular proteins

1981 • 360 citations

The 90-kDa heat shock protein, HSP90, binds and protects casein kinase II from self-aggregation and enhances its kinase activity.

1992 • 308 citations

A 90,000-dalton binding protein common to both steroid receptors and the Rous sarcoma virus transforming protein, pp60v-src.

1985 • 304 citations

A region in the steroid binding domain determines formation of the non-DNA-binding, 9 S glucocorticoid receptor complex.

1988 • 267 citations

A cellular protein that associates with the transforming protein of Rous sarcoma virus is also a heat-shock protein.

1981 • 246 citations

Hsp90 chaperonins possess ATPase activity and bind heat shock transcription factors and peptidyl prolyl isomerases.

1993 • 245 citations

Synthesis of the membrane fusion and hemagglutinin proteins of measles virus, using a novel baculovirus vector containing the beta-galactosidase gene

1990 • 245 citations

hsp82 Is an Essential Protein That Is Required in Higher Concentrations for Growth of Cells at Higher Temperatures

1989 • 244 citations

Antiglucocorticosteroid effects suggest why steroid hormone is required for receptors to bind DNA in vivo but not in vitro

1987 • 179 citations

Assembly of progesterone receptor with heat shock proteins and receptor activation are ATP mediated events.

1992 • 178 citations

Evidence that the 90-kDa heat shock protein (HSP90) exists in cytosol in heteromeric complexes containing HSP70 and three other proteins with Mr of 63,000, 56,000, and 50,000.

1991 • 177 citations

An immunophilin that binds M(r) 90,000 heat shock protein: main structural features of a mammalian p59 protein.

1992 • 168 citations

Heat shock protein 90 as a critical factor in maintaining glucocorticosteroid receptor in a nonfunctional state.

1991 • 163 citations

A rapid assay for binding estradiol to uterine receptor(s)

1970 • 159 citations

Reconstitution of Progesterone Receptor with Heat Shock Proteins

1990 • 149 citations

ATP induces a conformational change of the 90-kDa heat shock protein (hsp90).

1993 • 133 citations

Evidence that the hormone binding domain of steroid receptors confers hormonal control on chimeric proteins by determining their hormone-regulated binding to heat-shock protein 90

1993 • 130 citations

Interaction of the Mr = 90,000 heat shock protein with the steroid-binding domain of the glucocorticoid receptor.

1988 • 123 citations

Isoform composition and stoichiometry of the approximately 90-kDa heat shock protein associated with glucocorticoid receptors.

1988 • 114 citations

The transformed glucocorticoid receptor has a lower steroid-binding affinity than the nontransformed receptor

1990 • 103 citations

Hormonal regulation of the nuclear localization signals of the human glucocorticosteroid receptor

1992 • 80 citations

Chick oviduct glucocorticosteroid receptor

1985 • 67 citations

The cDNA-derived amino acid sequence of chick heat shock protein Mr 90,000 (HSP 90) reveals A “DNA like” structure: Potential site of interaction with steroid receptors

1989 • 64 citations

Chick heat-shock protein of Mr = 90,000, free or released from progesterone receptor, is in a dimeric form

1989 • 60 citations

Region-Specific Antiglucocorticoid Receptor Antibodies Selectively Recognize the Activated Form of the Ligand-Occupied Receptor and Inhibit the Binding of Activated Complexes to Deoxyribonucleic Acid

1989 • 57 citations

Cloning of the chick hsp 90 cDNA in expression vector

1985 • 56 citations

Hormone activation of baculovirus expressed progesterone receptors.

1992 • 38 citations

The steroid-binding properties of recombinant glucocorticoid receptor: A putative role for heat shock protein hsp90

1990 • 35 citations

Aldosterone metabolites and possible aldosterone precursors in hypertension

1983 • 35 citations

Evidence that the hormone-binding domain of the mouse glucocorticoid receptor directly represses DNA binding activity in a major portion of receptors that are “misfolded” after removal of hsp90.

1992 • 27 citations

A highly charged sequence of chick hsp90: A good candidate for interaction with steroid receptors

1989 • 14 citations

Subunit composition of the molybdate-stabilized non-activated glucocorticoid receptor from rat liver

1988 • 14 citations