Nucleotide sequence of both reciprocal translocation junction regions in a patient with Ph positive acute lymphoblastic leukaemia, with a breakpoint within the first intron of theBCRgene

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers

1982 • 6,153 citations

A New Consistent Chromosomal Abnormality in Chronic Myelogenous Leukaemia identified by Quinacrine Fluorescence and Giemsa Staining

1973 • 4,217 citations

Fused transcript of abl and bcr genes in chronic myelogenous leukaemia

1985 • 1,650 citations

Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22

1984 • 1,644 citations

Structural organization of the bcr gene and its role in the Ph′ translocation

1985 • 920 citations

Localization of the c-abl oncogene adjacent to a translocation break point in chronic myelocytic leukaemia

1983 • 848 citations

The Chronic Myelogenous Leukemia-Specific P210 Protein Is the Product of the bcr / abl Hybrid Gene

1986 • 820 citations

The Alu Family of Dispersed Repetitive Sequences

1982 • 611 citations

The Origin and Evolution of Retroposons

1985 • 555 citations

Acute Myelogenous Leukemia: A Human Cell Line Responsive to Colony-Stimulating Activity

1978 • 537 citations

Nonhomologous recombination in mammalian cells: role for short sequence homologies in the joining reaction.

1986 • 465 citations

Mutation in LDL Receptor: Alu-Alu Recombination Deletes Exons Encoding Transmembrane and Cytoplasmic Domains

1985 • 453 citations

A novel abl protein expressed in Philadelphia chromosome positive acute lymphoblastic leukaemia positive acute lymphoblastic leukaemia

1987 • 448 citations

Unique fusion of bcr and c-abl genes in Philadelphia chromosome positive acute lymphoblastic leukemia

1987 • 405 citations

Recombination at the human α-globin gene cluster: Sequence features and topological constraints

1987 • 345 citations

Unique Forms of the abl Tyrosine Kinase Distinguish Ph ¹ -Positive CML from Ph ¹ -Positive ALL

1987 • 344 citations

A novel c-abl protein product in Philadelphia-positive acute lymphoblastic leukaemia

1987 • 278 citations

Expression of a Distinctive BCR-ABL Oncogene in Ph ¹ -Positive Acute Lymphocytic Leukemia (ALL)

1988 • 252 citations

Role of chromosome translocations in human neoplasia

1987 • 226 citations

A new fused transcript in Philadelphia chromosome positive acute lymphocytic leukaemia

1987 • 201 citations

The Chronic Myelocytic Cell Line K562 Contains a Breakpoint in bcr and Produces a Chimeric bcr/c-abl Transcript

1986 • 192 citations

bcr rearrangement and translocation of the c-abl oncogene in Philadelphia positive acute lymphoblastic leukemia

1986 • 186 citations

The human cellular abl gene product in the chronic myelogenous leukemia cell line K562 has an associated tyrosine protein kinase activity

1985 • 184 citations

Inversion of chromosome 14 marks human T-cell chronic lymphocytic leukaemia

1984 • 174 citations

Clinical and biologic hallmarks of the Philadelphia chromosome in childhood acute lymphoblastic leukemia

1987 • 173 citations

A novel strategy for constructing clustered point mutations

1985 • 158 citations

Spontaneous deletion formation at the aprt locus of hamster cells: the presence of short sequence homologies and dyad symmetries at deletion termini.

1986 • 158 citations

A sex chromosome rearrangement in a human XX male caused by Alu—Alu recombination

1987 • 154 citations

Nonhomologous Recombination in Mammalian Cells: Role for Short Sequence Homologies in the Joining Reaction

1986 • 154 citations

The multicopy appearance of a large inverted duplication and the sequence at the inversion joint suggest a new model for gene amplification.

1988 • 125 citations

Novel chimaeric protein expressed in Philadelphia positive acute lymphoblastic leukaemia

1987 • 102 citations

Molecular analysis of both translocation products of a Philadelphia-positive CML patient

1986 • 78 citations

Retroviral DNA integration

1985 • 76 citations

A conserved sequence at c-myc oncogene chromosomal translocation breakpoints in plasmacytomas

1984 • 63 citations

Characterization of the Rearranged tpr-met Oncogene Breakpoint

1987 • 53 citations

Heterogeneity of genomic fusion of BCR and ABL in Philadelphia chromosome-positive acute lymphoblastic leukemia.

1988 • 51 citations

The Third International Workshop on Chromosomes in Leukemia

1981 • 45 citations

Characterization of the translocation breakpoint in a patient with Philadelphia positive, bcr negative acute lymphoblastic leukaemia.

1988 • 15 citations

Molecular Genetics of Antigen Receptors and Associated Chromosomal Abnormalities in Human Leukemias

1986 • 11 citations