Regulation of ionotropic glutamate receptors following subchronic and chronic treatment with typical and atypical antipsychotics

The functional anatomy of basal ganglia disorders

1989 • 5,166 citations

Recent advances in the phencyclidine model of schizophrenia

1991 • 2,886 citations

Molecular Diversity of Glutamate Receptors and Implications for Brain Function

1992 • 2,535 citations

The Excitatory Amino Acid Receptors: Their Classes, Pharmacology, and Distinct Properties in the Function of the Central Nervous System

1989 • 2,203 citations

Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine

1991 • 2,008 citations

Dopamine in schizophrenia: a review and reconceptualization

1991 • 1,963 citations

Requirement for Glycine in Activation of NMDA-Receptors Expressed in Xenopus Oocytes

1988 • 1,415 citations

Interactions between glutamatergic and monoaminergic systems within the basal ganglia-implications for schizophrenia and Parkinson's disease

1990 • 1,102 citations

The current status of the dopamine hypothesis of schizophrenia

1988 • 962 citations

Basal Ganglia and Limbic System Pathology in Schizophrenia

1985 • 891 citations

Cooperative Modulation of [³H]MK‐801 Binding to the N‐Methyl‐d‐Aspartate Receptor‐Ion Channel Complex by l‐Glutamate, Glycine, and Polyamines

1988 • 755 citations

Typical and atypical neuroleptics: differential effects of chronic administration on the activity of A9 and A10 midbrain dopaminergic neurons

1983 • 680 citations

Clinical studies on the mechanism of action of clozapine: the dopamine-serotonin hypothesis of schizophrenia

1989 • 600 citations

Differential Effects of Classical and Atypical Antipsychotic Drugs on A9 and A10 Dopamine Neurons

1983 • 589 citations

Cell loss in the hippocampus of schizophrenics

1986 • 496 citations

The NMDA antagonist MK-801 causes marked locomotor stimulation in monoamine-depleted mice

1989 • 426 citations

Excitatory amino acid receptors in the brain: membrane binding and receptor autoradiographic approaches

1990 • 397 citations

Frontal Cortical and Left Temporal Glutamatergic Dysfunction in Schizophrenia

1989 • 392 citations

Autoradiographic characterization of N-methyl-D-aspartate-, quisqualate- and kainate-sensitive glutamate binding sites.

1985 • 374 citations

Quantitative autoradiographic analysis of glutamate binding sites in the hippocampal formation in normal and schizophrenic brain post mortem

1990 • 246 citations

Increased [3H]kainic acid binding in the prefrontal cortex in schizophrenia

1983 • 201 citations

Clozapine is a potent and selective muscarinic M4 receptor agonist

1994 • 179 citations

Dopaminergic regulation of striatal acetylcholine release: importance of D1 and N-methyl-D-aspartate receptors.

1991 • 123 citations

Effects of acute and chronic treatments with clozapine and haloperidol on serotonin (5-HT2) and dopamine (D2) receptors in the rat brain

1989 • 122 citations

An open label trial of raclopride in acute schizophrenia. Confirmation of D2-dopamine receptor occupancy by PET

1988 • 112 citations

Chronic treatment with clozapine or haloperidol differentially regulates dopamine and serotonin receptors in rat brain

1990 • 112 citations

Glutamate: a new target in schizophrenia?

1990 • 98 citations

Excitatory Amino Acid Receptors in Schizophrenia

1993 • 90 citations

Role of N-methyl-d-aspartate (NMDA) receptors in experimental catalepsy in rats

1990 • 72 citations

Effect of haloperidol and clozapine on the density of “perforated” synapses in caudate, nucleus accumbens, and medial prefrontal cortex

1992 • 63 citations

Chronic haloperidol treatment enhances binding to NMDA receptors in rat cortex

1993 • 56 citations

Distinct sites of dopaminergic and glutamatergic regulation of haloperidol-induced catalepsy within the rat caudate-putamen

1994 • 51 citations

Striatal N-methyl-D-aspartate receptors in haloperidol-induced catalepsy

1991 • 51 citations

Chronic phencyclidine treatment decreases phencyclidine and dopamine receptors in rat brain

1982 • 46 citations

Quantitative autoradiographic characterization of the binding of (+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5, 10-imine ([3H]MK-801) in rat brain: regional effects of polyamines.

1991 • 45 citations

Chronic haloperidol treatment up-regulates rat brain PCP receptors

1987 • 24 citations

Drug-induced oral dyskinesias in rats after traditional and new neuroleptics

1995 • 21 citations

Chronic administration of MK-801 and the NMDA receptor: Further evidence for reduced sensitivity of the primary acceptor site from studies with the cortical wedge preparation

1990 • 17 citations