Peripheral blood lymphocytes as target cells of retroviral vector- mediated gene transfer

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

1982 • 2,753 citations

Improved retroviral vectors for gene transfer and expression.

1989 • 1,997 citations

Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

1983 • 1,857 citations

Redesign of Retrovirus Packaging Cell Lines To Avoid Recombination Leading to Helper Virus Production

1986 • 1,276 citations

A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains

1984 • 1,262 citations

Expression and structure of the human NGF receptor

1986 • 956 citations

Human gene therapy comes of age

1992 • 927 citations

Polymerase Chain Reaction with Single-Sided Specificity: Analysis of T Cell Receptor δ Chain

1989 • 640 citations

Expression of a foreign gene in myeloid and lymphoid cells derived from multipotent haematopoietic precursors

1985 • 598 citations

Overexpression of TAR sequences renders cells resistant to human immunodeficiency virus replication

1990 • 437 citations

Treatment of genetic defects in hematopoietic cell function by gene transfer

1991 • 225 citations

Improved gene expression upon transfer of the adenosine deaminase minigene outside the transcriptional unit of a retroviral vector.

1989 • 192 citations

Expression of human adenosine deaminase in nonhuman primates after retrovirus-mediated gene transfer.

1987 • 187 citations

Complete sequence and structure of the gene for human adenosine deaminase

1986 • 161 citations

Human gene transfer: characterization of human tumor-infiltrating lymphocytes as vehicles for retroviral-mediated gene transfer in man.

1990 • 145 citations

Lymphocytes as cellular vehicles for gene therapy in mouse and man.

1991 • 138 citations

An in Vivo Model of Somatic Cell Gene Therapy for Human Severe Combined Immunodeficiency

1991 • 129 citations

Transfer and expression of cloned genes using retrovial vectors

1986 • 103 citations

Overexpression of RRE-derived sequences inhibits HIV-1 replication in CEM cells.

1992 • 99 citations

Retroviral vector-mediated high-efficiency expression of adenosine deaminase (ADA) in hematopoietic long-term cultures of ADA-deficient marrow cells.

1989 • 73 citations

Correction of CD18-Deficient Lymphocytes by Retrovirus-Mediated Gene Transfer

1990 • 60 citations

Transfer of the ADA Gene into Bone Marrow Cells and Peripheral Blood Lymphocytes for the Treatment of Patients Affected by ADA-Deficient SCID

1993 • 55 citations

Transfer of the ADA gene into human ADA-deficient T lymphocytes reconstitutes specific immune functions

1992 • 44 citations

Retrovirus-mediated gene transfer into CD4+ and CD8+ human T cell subsets derived from tumor-infiltrating lymphocytes and peripheral blood mononuclear cells

1991 • 33 citations