5′-Long Terminal Repeat-Selective CpG Methylation of Latent Human T-Cell Leukemia Virus Type 1 Provirus In Vitro and In Vivo

Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma

1980 • 5,022 citations

ANTIBODIES TO HUMAN T-LYMPHOTROPIC VIRUS TYPE-I IN PATIENTS WITH TROPICAL SPASTIC PARAPARESIS

1985 • 2,840 citations

Adult T-cell leukemia: antigen in an ATL cell line and detection of antibodies to the antigen in human sera.

1981 • 2,281 citations

Adult T-cell leukemia: clinical and hematologic features of 16 cases

1977 • 2,119 citations

The DNA methyltransferases of mammals

2000 • 1,981 citations

Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia

1997 • 1,960 citations

High sensitivity mapping of methylated cytosines

1994 • 1,863 citations

Adult T-cell leukemia: clinical and hematologic features of 16 cases

1977 • 1,750 citations

Role for DNA methylation in genomic imprinting

1994 • 1,695 citations

Interspersed repeats and other mementos of transposable elements in mammalian genomes

1999 • 959 citations

Antibodies to adult t‐cell leukemia‐virus‐associated antigen (atla) in sera from patients with atl and controls in japan: A nation‐wide sero‐epidemiologic study

1982 • 607 citations

Mapping Patterns of CpG Island Methylation in Normal and Neoplastic Cells Implicates Both Upstream and Downstream Regions inde Novo Methylation

1997 • 323 citations

Clonal expansion of human T-cell leukemia virus type I-infected cells in asymptomatic and symptomatic carriers without malignancy

1995 • 308 citations

HTLV‐I Uveitis: A Distinct Clinical Entity Caused by HTLV‐I

1992 • 292 citations

Detection of mRNA for the tax1/rex1 gene of human T-cell leukemia virus type I in fresh peripheral blood mononuclear cells of adult T-cell leukemia patients and viral carriers by using the polymerase chain reaction.

1989 • 289 citations

Two types of defective human T-lymphotropic virus type I provirus in adult T-cell leukemia

1996 • 248 citations

DNA methylation and gene expression: endogenous retroviral genome becomes infectious after molecular cloning.

1981 • 231 citations

Existence of escape mutant in HTLV-I tax during the development of adult T-cell leukemia

2001 • 179 citations

DNA methylation in the Alu sequences of diploid and haploid primary human cells.

1993 • 175 citations

Human T-cell leukemia virus (HTLV-I) transcripts in fresh and cultured cells of patients with adult T-cell leukemia.

1984 • 162 citations

Gene Silencing

1999 • 157 citations

HTLV-1-associated diseases.

1997 • 144 citations

High human T-cell lymphotropic virus type I proviral DNA load with polyclonal integration in peripheral blood mononuclear cells of French West Indian, Guianese, and African patients with tropical spastic paraparesis

1990 • 129 citations

Developmental differences in methylation of human Alu repeats.

1993 • 129 citations

5-Azacytidine induction of mouse endogenous type C virus and suppression of DNA methylation.

1981 • 99 citations

A novel diagnostic method of adult T-cell leukemia: monoclonal integration of human T-cell lymphotropic virus type I provirus DNA detected by inverse polymerase chain reaction

1994 • 97 citations

Human T-cell leukemia virus type-1 (HTLV-1) Tax is expressed at the same level in infected cells of HTLV-1-associated myelopathy or tropical spastic paraparesis patients as in asymptomatic carriers but at a lower level in adult T-cell leukemia cells

1995 • 93 citations

Variable expression of latent membrane protein in nasopharyngeal carcinoma can be related to methylation status of the Epstein-Barr virus BNLF-1 5'-flanking region

1991 • 78 citations

Human T lymphotropic virus type 1 uveitis.

1994 • 67 citations

Somatic Mutation in Human T-Cell Leukemia Virus Type 1 Provirus and Flanking Cellular Sequences During Clonal Expansion In Vivo

2001 • 64 citations

Lymphoid Organs as a Major Reservoir for Human T-Cell Leukemia Virus Type 1 in Experimentally Infected Squirrel Monkeys (Saimiri sciureus): Provirus Expression, Persistence, and Humoral and Cellular Immune Responses

2000 • 61 citations

Host Sequences Flanking the Human T-Cell Leukemia Virus Type 1 Provirus In Vivo

2000 • 46 citations

Human T-lymphotropic virus type I transcriptional regulation by methylation.

1990 • 39 citations

Methylation of human T-cell leukemia virus proviral DNA and viral RNA expression in short- and long-term cultures of infected cells

1984 • 39 citations

Transcriptional block of HTLV-I LTR by sequence-specific methylation

1991 • 32 citations

Mouse mammary tumor virus: specific methylation patterns of proviral DNA in normal mouse tissues

1984 • 27 citations

Developmental Differences in Methylation of Human Alu Repeats

1993 • 26 citations

Methylation pattern of human T‐cell leukemia virus in vivo and in vitro: pX and LTR regions are hypomethylated in vivo

1985 • 25 citations

In Vivo Genomic Footprinting of the Human T-Cell Leukemia Virus Type 1 (HTLV-1) Long Terminal Repeat Enhancer Sequences in HTLV-1-Infected Human T-Cell Lines with Different Levels of Tax I Activity

2000 • 24 citations

Antibodies against human T‐cell leukemia/lymphoma virus (HTLV) and expression of HTLV p19 antigen in relatives of a T‐cell leukemia patient originating from Surinam

1983 • 24 citations

Inhibition of Human T Cell Leukaemia Virus Type I Long Terminal Repeat Expression by DNA Methylation: Implications for Latency

1994 • 18 citations

An Origin of DNA Replication (oriP) in Highly Methylated Episomal Epstein-Barr Virus DNA Localizes to a 4.5-kb Unmethylated Region

1993 • 15 citations

Basis of HTLV Type 1 Target Site Selection

2000 • 14 citations

Induction of Tax I Expression in MT-4 Cells by 5-Azacytidine Leads to Protein Binding in the HTLV-I LTR in Vivo

2001 • 12 citations

Virus inactivation in a proportion of human T-cell leukaemia virus type I-infected T-cell clones arises through naturally occurring mutations

2000 • 7 citations

Methylation pattern of the bovine leukemia provirus genome in bovine leukemic cells.

1985 • 4 citations