Stable knockdown of MYCN by lentivirus-based RNAi inhibits human neuroblastoma cells growth in vitro and in vivo

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

2001 • 9,275 citations

A System for Stable Expression of Short Interfering RNAs in Mammalian Cells

2002 • 4,334 citations

Asymmetry in the Assembly of the RNAi Enzyme Complex

2003 • 2,761 citations

Functional siRNAs and miRNAs Exhibit Strand Bias

2003 • 2,516 citations

A Lentiviral RNAi Library for Human and Mouse Genes Applied to an Arrayed Viral High-Content Screen

2006 • 1,752 citations

A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference

2003 • 1,515 citations

Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells

2002 • 965 citations

Targeted expression of MYCN causes neuroblastoma in transgenic mice

1997 • 830 citations

Molecular Biology of Neuroblastoma

1999 • 644 citations

326. A Versatile Tool for Conditional Gene Expression and Knockdown

2006 • 354 citations

A versatile tool for conditional gene expression and knockdown

2006 • 344 citations

MYCN silencing induces differentiation and apoptosis in human neuroblastoma cells

2006 • 130 citations

Neoplastic transformation by the human gene N-myc.

1987 • 124 citations

Effects of MYCN Antisense Oligonucleotide Administration on Tumorigenesis in a Murine Model of Neuroblastoma

2003 • 102 citations

Decrease of proliferation rate and induction of differentiation by a MYCN antisense DNA oligomer in a human neuroblastoma cell line.

1991 • 100 citations

Anti-gene peptide nucleic acid specifically inhibits MYCN expression in human neuroblastoma cells leading to cell growth inhibition and apoptosis

2005 • 84 citations

The MYCN Oncogene as a Specific and Selective Drug Target for Peripheral and Central Nervous System Tumors

2005 • 70 citations

Silencing of MYCN by RNA interference induces growth inhibition, apoptotic activity and cell differentiation in a neuroblastoma cell line with MYCN amplification

2007 • 64 citations

Antisense inhibition of single copy N-myc expression results in decreased cell growth without reduction of c-myc protein in a neuroepithelioma cell line.

1990 • 52 citations

Use of RNA interference to elucidate the effect of MYCN on cell cycle in neuroblastoma

2007 • 44 citations

Targeted inhibition of NMYC by peptide nucleic acid in N-myc amplified human neuroblastoma cells: cell-cycle inhibition with induction of neuronal cell differentiation and apoptosis

2004 • 40 citations

Synergism of BARF1 with Ras Induces Malignant Transformation in Primary Primate Epithelial Cells and Human Nasopharyngeal Epithelial Cells

2009 • 38 citations

Pharmacokinetics of (111)In-labeled triplex-forming oligonucleotide targeting human N-myc gene.

2002 • 7 citations

Pharmacokinetics of 111In-labeled Triplex-forming Oligonucleotide Targeting Human N-myc Gene

2002 • 4 citations