SV40 large T antigen trans-activates the long terminal repeats of a large family of human endogenous retrovirus-like sequences

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

1982 • 2,753 citations

SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene

1988 • 1,490 citations

Retinoic acid induces neuronal differentiation of a cloned human embryonal carcinoma cell line in vitro

1984 • 808 citations

Pluripotent embryonal carcinoma clones derived from the human teratocarcinoma cell line Tera-2. Differentiation in vivo and in vitro.

1984 • 612 citations

Simian Virus 40 Deoxyribonucleic Acid Synthesis: the Viral Replicon

1972 • 609 citations

Transgenic mice harboring SV40 t-antigen genes develop characteristic brain tumors

1984 • 492 citations

HUMAN TUMOR SUPPRESSOR GENES

1990 • 266 citations

Regulation of simian virus 40 early transcription in vitro by a purified tumor antigen.

1980 • 254 citations

Autoregulation of simian virus 40 gene A by T antigen.

1976 • 248 citations

Retinoblastoma in transgenic mice

1990 • 246 citations

Identification of the oncogenic substance in rhesus monkey kidney cell cultures as simian virus 40

1962 • 246 citations

Stimulation of simian virus 40 late gene expression by simian virus 40 tumor antigen.

1984 • 207 citations

Transient gene expression control: effects of transfected DNA stability and trans-activation by viral early proteins.

1985 • 174 citations

Identification of a retrovirus-like repetitive element in human DNA.

1984 • 147 citations

SV40 stimulates expression of the transacting factor Sp1 at the mRNA level.

1990 • 124 citations

trans Activation of the Simian Virus 40 Late Transcription Unit by T-Antigen

1985 • 118 citations

The large tumor antigen of simian virus 40 encodes at least two distinct transforming functions

1989 • 117 citations

Analysis of an activatable promoter: sequences in the simian virus 40 late promoter required for T-antigen-mediated trans activation.

1985 • 115 citations

Trans-activation of RNA polymerase II and III promoters by SV40 small t antigen

1988 • 98 citations

Site-specific methylation: effect on DNA modification methyltransferases and restriction endonucleases

1991 • 94 citations

The simian virus 40 large T antigen. A lot packed into a little.

1987 • 76 citations

Mapping the transcriptional transactivation function of simian virus 40 large T antigen

1991 • 69 citations

Autonomous expression of RTVL-H endogenous retroviruslike elements in human cells

1990 • 69 citations

Stimulation of the adenovirus E2 promoter by simian virus 40 T antigen or E1A occurs by different mechanisms.

1986 • 67 citations

Functional heterogeneity of a large family of human LTR-like promoters and enhancers

1990 • 60 citations

Polyadenylation function and sequence variability of the long terminal repeats of the human endogenous retrovirus-like family RTVL-H

1989 • 45 citations

trans Activation of the simian virus 40 late transcription unit by T-antigen.

1985 • 40 citations

Both trans-acting factors and chromatin structure are involved in the regulation of transcription from the early and late promoters in simian virus 40 chromosomes

1985 • 40 citations

Members of the RTVL-H family of human endogenous retrovirus-like elements are expressed in placenta

1989 • 39 citations

Simian virus 40 T antigen alters the binding characteristics of specific simian DNA-binding factors.

1988 • 39 citations

Stimulation of RNA synthesis in isolated nuclei by partially purified preparations of simian virus 40 T-antigen.

1977 • 33 citations

Activity of simian DNA-binding factors is altered in the presence of simian virus 40 (SV40) early proteins: characterization of factors binding to elements involved in activation of the SV40 late promoter

1990 • 32 citations

The long terminal repeat of the intracisternal A particle as a target for transactivation by oncogene products

1986 • 31 citations

SV40 mutants with an altered small-t protein are tumorigenic in newborn hamsters

1981 • 30 citations

Stimulation of RNA synthesis in isolated nucleoli by preparations of simian virus 40 T antigen

1978 • 27 citations

Chromosomal distribution of the RTVL-H family of human endogenous retrovirus-like sequences

1988 • 26 citations

Transactivation of both early and late simian virus 40 promoters by large tumor antigen does not require nuclear localization of the protein.

1989 • 25 citations

Effect of the SV40 T antigen on the posttranscriptional regulation of the proliferating cell nuclear antigen and DNA polymerase-alpha genes.

1991 • 24 citations

Stimulation of the Human Heat Shock Protein 70 Promoter in Vitro by Simian Virus 40 Large T Antigen

1989 • 23 citations

trans-activation of cellular and viral promoters by a transforming nonkaryophilic simian virus 40 large T antigen

1987 • 17 citations

Activation of the human ε- and β-globin promoters by SV40 T antigen

1989 • 11 citations