Post-injury treatment with GM1 ganglioside reduces nociceptive behaviors and spinal cord metabolic activity in rats with experimental peripheral mononeuropathy

THE [¹⁴C]DEOXYGLUCOSE METHOD FOR THE MEASUREMENT OF LOCAL CEREBRAL GLUCOSE UTILIZATION: THEORY, PROCEDURE, AND NORMAL VALUES IN THE CONSCIOUS AND ANESTHETIZED ALBINO RAT¹

1977 • 5,986 citations

A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man

1988 • 5,129 citations

The formalin test: A quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats

1977 • 2,494 citations

Glutamate and the pathophysiology of hypoxic–ischemic brain damage

1986 • 2,428 citations

Evidence for a central component of post-injury pain hypersensitivity

1983 • 2,103 citations

The induction and maintenance of central sensitization is dependent on N -methyl-d-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states

1991 • 1,963 citations

The cytoarchitectonic organization of the spinal cord in the rat. I. The lower thoracic and lumbosacral cord

1984 • 736 citations

Cerebral hypoxia: some new approaches and unanswered questions

1990 • 674 citations

Peripheral Neuropathy

1984 • 654 citations

Further evidence for ‘pain-related’ behaviours in a model of unilateral peripheral mononeuropathy

1990 • 504 citations

Non-competitive antagonists of excitatory amino acid receptors

1987 • 502 citations

Mapping of Functional Neural Pathways by Autoradiographic Survey of Local Metabolic Rate with [ ¹⁴ C]Deoxyglucose

1975 • 432 citations

Proceedings of the Vth World Congress on Pain

1988 • 349 citations

Ongoing activity in severed nerves: source and variation with time

1978 • 334 citations

The Role of Glutamate in Neurotransmission and in Neurologic Disease

1986 • 294 citations

Intrathecal MK-801 and local nerve anesthesia synergistically reduce nociceptive behaviors in rats with experimental peripheral mononeuropathy

1992 • 286 citations

Psychological and Neural Mechanisms of Pain

1988 • 282 citations

Psychophysical observations on patients with neuropathic pain relieved by a sympathetic block

1989 • 249 citations

Ongoing activity in peripheral nerve: Injury discharge

1974 • 240 citations

Neurotransmitter-mediated mechanisms of traumatic brain injury: acetylcholine and excitatory amino acids.

1992 • 213 citations

Pretreatment with Phencyclidine, an N-Methyl-<scp>d</scp>-Aspartate Antagonist, Attenuates Long-Term Behavioral Deficits in the Rat Produced by Traumatic Brain Injury

1988 • 201 citations

Mechanisms of blockade of excitatory amino acid receptor channels

1990 • 199 citations

Muscle reinnervation—III. Motoneuron sprouting capacity, enhancement by exogenous gangliosides

1983 • 186 citations

Focal Cortical Seizures Cause Distant Thalamic Lesions

1982 • 172 citations

The role(s) of Gangliosides in neural differentiation and repair: A perspective

1990 • 155 citations

Psychological and Neural Mechanisms of Pain

1988 • 146 citations

CGS‐19755, A competitive NMDA receptor antagonist, reduces calcium‐calmodulin binding and improves outcome after global cerebral ischemia

1990 • 119 citations

Spatial patterns of spinal cord [14C]-2-deoxyglucose metabolic activity in a rat model of painful peripheral mononeuropathy

1992 • 110 citations

The Effects of Mechanical Stimulation on Some Electrical Properties of Axons

1962 • 105 citations

Alterations in myelinated fibres in the sciatic nerve of rats after constriction: possible relationships between the presence of abnormal small myelinated fibres and pain-related behaviour

1990 • 100 citations

Glutamate immunoreactivity in rat dorsal root axons

1989 • 99 citations

Gangliosides (GM1 and AGF2) reduce mortality due to ischemia: protection of membrane function.

1987 • 97 citations

Gangliosides and Neuronal Plasticity

1986 • 89 citations

Spatial distribution of nociceptive processing in the rat spinal cord

1991 • 87 citations

GM1 ganglioside enhances regrowth of noradrenaline nerve terminals in rat cerebral cortex lesioned by the neurotoxin 6-hydroxydopamine

1984 • 83 citations

Strychnine-enhanced transsynaptic degeneration of dorsal horn neurons in rats with an experimental painful peripheral neuropathy

1989 • 74 citations

Acute effects of GM1 ganglioside: Reduction in both behavioral asymmetry and loss of Na+,K+-ATPase after nigrostriatal transection

1986 • 67 citations

Double‐blind evaluation of monosialoganglioside (GM₁) therapy in stroke

1984 • 60 citations

Identification of α-Galactose (α-Fucose)-asialo-GM1 Glycolipid Expressed by Subsets of Rat Dorsal Root Ganglion Neurons

1989 • 58 citations

ATPase Activity Defects in Alloxan-Induced Diabetic Sciatic Nerve Recovered by Ganglioside Treatment

1988 • 54 citations

Gangliosides: the relevance of current research to neurosurgery

1991 • 54 citations

The relationship between CNS metabolism and cytoarchitecture: A review of 14C-deoxyglucose studies with correlation to cytochrome oxidase histochemistry

1989 • 52 citations

Ganglioside-induced regeneration and reestablishment of axonal continuity in spinal cord-transected rats

1986 • 51 citations

The NMDA-antagonist MK-801 reduces extracellular amino acid levels during hypoglycemia and prevents striatal damage

1988 • 50 citations

Pretreatment with gangliosides reduces abnormal nociceptive responses associated with a rodent peripheral mononeuropathy

1992 • 48 citations

Hypoglycemic neurotoxicity in vitro: Involvement of excitatory amino acid receptors and attenuation by monosialoganglioside GM1

1990 • 47 citations

GM1 Ganglioside treatment after global ischemia protects changes in membrane fatty acids and properties of Na+, K+‐ATPase and Mg2+‐ATPase

1989 • 47 citations

2-deoxy[14C]glucose uptake in the rat hypoglossal nucleus after nerve transection

1980 • 45 citations

Regional changes in spinal cord glucose metabolism in a rat model of painful neuropathy

1991 • 44 citations

Aspartate immunoreactive axons in normal rat L4 dorsal roots

1989 • 44 citations

Deafferentation Pain Syndromes

1989 • 44 citations

Excitatory amino acid neurotoxicity in cultured retinal neurons: Involvement of N‐methyl‐D‐Aspartate (NMDA) and Non‐NMDA receptors and effect of ganglioside GM1

1990 • 43 citations

Monosialoganglioside internal ester stimulates the dopaminergic reinnervation of the striatum after unilateral hemitransection in rat

1984 • 40 citations

Reduction of anterograde degeneration in brain damaged rats by GM1-gangliosides

1987 • 37 citations

Treatment of denervated muscle by gangliosides

1979 • 36 citations

Ganglioside Treatment and Improved Axonal Regeneration Capacity in Experimental Diabetic Neuropathy

1989 • 34 citations

Ganglioside treatment of vincristine-induced neuropathy. An electrophysiologic study

1988 • 31 citations

Ganglioside treatment: Reduction of CNS injury and facilitation of functional recovery

1987 • 31 citations

Hypoxic-ischemic damage and the neuroprotective effects of GM1 ganglioside.

1990 • 24 citations

Acute Effects of Gangliosides on CNS Injury

1986 • 23 citations

Ganglioside Distribution at Different Levels of Organization and its Biological Implications

1984 • 22 citations

Enhanced sprouting of retinotectal fibers after early superior colliculus lesions in hamsters treated with gangliosides

1988 • 19 citations

Efficacy of ganglioside treatment in reducing functional alterations induced by vincristine in rabbit peripheral nerves

1990 • 17 citations

Facilitated-Establishment of Contacts and Synapses in Neuronal Cultures: Ganglioside-Mediated Neurite Sprouting and Outgrowth

1986 • 11 citations

Ganglioside Therapy of Peripheral Neuropathies: A Review of Clinical Literature

1986 • 10 citations

Glutamate receptors, protein kinase C translocation, and gangliosides.

1988 • 7 citations

Subacute Phase of Stroke Treated with Ganglioside GM1

1986 • 6 citations

Differential actions of neurotrophic factors on lesion-induced damage of the serotonergic neurons projecting to the hippocampus

1988 • 6 citations

Modulation of Neurite Outgrowth and Ganglioside Associated Changes in Cerebral Neurons and PC12 Pheochromocytoma Cells

1986 • 1 citations