The molecular switch hypothesis fails to explain the inconsistent effects of the metabotropic glutamate receptor antagonist MCPG on long-term potentiation

A synaptic model of memory: long-term potentiation in the hippocampus

1993 • 11,303 citations

Synaptic plasticity: LTP and LTD

1994 • 1,301 citations

Metabotropic glutamate receptors in brain function and pathology

1993 • 799 citations

Induction of LTP in the hippocampus needs synaptic activation of glutamate metabotropic receptors

1993 • 736 citations

Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1

1994 • 730 citations

Metabotropic glutamate receptors: Synaptic transmission, modulation, and plasticity

1994 • 713 citations

Reduced hippocampal long-term potentiation and context-specific deficit in associative learning in mGluR1 mutant mice

1994 • 607 citations

Agonists at metabotropic glutamate receptors presynaptically inhibit EPSCs in neonatal rat hippocampus.

1991 • 431 citations

A molecular switch activated by metabotropic glutamate receptors regulates induction of long-term potentiation

1994 • 405 citations

Protein kinase C modulation of NMDA currents: an important link for LTP induction

1992 • 350 citations

Novel form of long-term potentiation produced by a K+channel blocker in the hippocampus

1991 • 321 citations

Low-frequency stimulation erases LTP through an NMDA receptor-mediated activation of protein phosphatases.

1994 • 281 citations

Characterisation of LTP induced by the activation of glutamate metabotropic receptors in area CA1 of the hippocampus

1993 • 262 citations

Metabotropic glutamate receptors are differentially regulated during development

1994 • 238 citations

Quisqualate Metabotropic Receptors Modulate NMDA Currents and Facilitate Induction of Long‐Term Potentiation Through Protein Kinase C

1992 • 200 citations

Long-lasting enhancement of NMDA receptor-mediated synaptic transmission by metabotropic glutamate receptor activation

1994 • 173 citations

MCPG Antagonizes Metabotropic Glutamate Receptors but not Long‐term Potentiation in the Hippocampus

1994 • 166 citations

Examination of TEA-induced synaptic enhancement in area CA1 of the hippocampus: the role of voltage-dependent Ca2+ channels in the induction of LTP

1993 • 165 citations

Selective activation of quisqualate metabotropic receptor potentiates NMDA but not AMPA responses

1991 • 135 citations

(RS)-alpha-methyl-4-carboxyphenylglycine neither prevents induction of LTP nor antagonizes metabotropic glutamate receptors in CA1 hippocampal neurons

1993 • 114 citations

Trans-ACPD enhances long-term potentiation in the hippocampus

1991 • 107 citations

Activation of metabotropic glutamate receptors induces long-term depression of GABAergic inhibition in hippocampus

1993 • 97 citations

Multiple metabotropic glutamate receptors regulate hippocampal function

1992 • 57 citations

Developmental changes in the effects of metabotropic glutamate receptor antagonists on CA1 long-term potentiation in rat hippocampal slices

1994 • 34 citations

(RS)-α-Methyl-4-carboxyphenylglycine (MCPG) does not block theta burst-induced long-term potentiation in area CA1 of rat hippocampal slices

1994 • 31 citations

Major differences between long-term potentiation and ACPD-induced slow onset potentiation in hippocampus

1994 • 29 citations

Synaptic Plasticity: A molecular switch for memory

1994 • 10 citations