Secondary structure of the mammalian 70-kilodalton heat shock cognate protein analyzed by circular dichroism spectroscopy and secondary structure prediction

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold.

1982 • 5,284 citations

THE HEAT-SHOCK PROTEINS

1988 • 5,214 citations

Calculation of protein extinction coefficients from amino acid sequence data

1989 • 5,198 citations

Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins

1978 • 4,566 citations

Structure of the human class I histocompatibility antigen, HLA-A2

1987 • 3,453 citations

Spectroscopic Determination of Tryptophan and Tyrosine in Proteins^*

1967 • 3,423 citations

Prediction of protein conformation

1974 • 3,327 citations

The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens

1987 • 2,403 citations

[11] Calculation of protein conformation from circular dichroism

1986 • 1,625 citations

Speculations on the functions of the major heat shock and glucose-regulated proteins

1986 • 1,574 citations

A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides

1988 • 1,504 citations

An hsp70-like protein in the ER: Identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein

1986 • 1,457 citations

Amino Acid Preferences for Specific Locations at the Ends of α Helices

1988 • 1,356 citations

Interaction of Hsp 70 with Newly Synthesized Proteins: Implications for Protein Folding and Assembly

1990 • 1,293 citations

The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins

1988 • 1,292 citations

Structural patterns in globular proteins

1976 • 1,286 citations

70K heat shock related proteins stimulate protein translocation into microsomes

1988 • 1,276 citations

Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life.

1988 • 1,140 citations

Abnormal Proteins Serve as Eukaryotic Stress Signals and Trigger the Activation of Heat Shock Genes

1986 • 904 citations

Posttranslational association of immunoglobulin heavy chain binding protein with nascent heavy chains in nonsecreting and secreting hybridomas.

1986 • 896 citations

Comparison of super-secondary structures in proteins

1973 • 885 citations

Polypeptide chain binding proteins: Catalysts of protein folding and related processes in cells

1989 • 884 citations

How calmodulin binds its targets: sequence independent recognition of amphiphilic α-helices

1990 • 839 citations

Determination of protein secondary structure in solution by vacuum ultraviolet circular dichroism

1980 • 777 citations

Peptide Binding and Release by Proteins Implicated as Catalysts of Protein Assembly

1989 • 763 citations

Measurement of protein by spectrophotometry at 205 nm

1974 • 742 citations

Ultraviolet fluorescence of the aromatic amino acids

1957 • 734 citations

Variable selection method improves the prediction of protein secondary structure from circular dichroism spectra

1987 • 709 citations

Uncoating ATPase is a member of the 70 kilodalton family of stress proteins

1986 • 607 citations

[27] Circular dichroism and optical rotatory dispersion of proteins and polypeptides

1973 • 547 citations

Nuclear and nucleolar localization of the 72,000-dalton heat shock protein in heat-shocked mammalian cells.

1984 • 522 citations

Thermolability of ubiquitin-activating enzyme from the mammalian cell cycle mutant ts85

1984 • 522 citations

Automatic identification of secondary structure in globular proteins

1977 • 507 citations

Molecular chaperones: proteins essential for the biogenesis of some macromolecular structures

1989 • 491 citations

Model for signal sequence recognition from amino-acid sequence of 54K subunit of signal recognition particle

1989 • 474 citations

Hsp70 accelerates the recovery of nucleolar morphology after heat shock.

1984 • 456 citations

An enzyme that removes clathrin coats: purification of an uncoating ATPase.

1984 • 449 citations

Sensitivity of circular dichroism to protein tertiary structure class

1983 • 412 citations

Cultured animal cells exposed to amino acid analogues or puromycin rapidly synthesize several polypeptides

1980 • 395 citations

The mechanism of protein folding. Implications of in vitro refolding models for de novo protein folding and translocation in the cell

1990 • 372 citations

The relationship of N-linked glycosylation and heavy chain-binding protein association with the secretion of glycoproteins.

1987 • 357 citations

Specific interaction between the p53 cellular tumour antigen and major heat shock proteins

1986 • 354 citations

Involvement of ATP in the nuclear and nucleolar functions of the 70 kd heat shock protein.

1985 • 327 citations

Interactions of misfolded influenza virus hemagglutinin with binding protein (BiP).

1989 • 312 citations

The 70-kd mammalian heat shock proteins are structurally and functionally related to the uncoating protein that releases clathrin triskelia from coated vesicles.

1985 • 301 citations

The ATPase core of a clathrin uncoating protein.

1987 • 259 citations

Structure and expression of a human gene coding for a 71 kd heat shock ‘cognate’ protein

1987 • 254 citations

A peptide binding protein having a role in antigen presentation is a member of the HSP70 heat shock family.

1989 • 246 citations

Enzymatic recycling of clathrin from coated vesicles

1986 • 237 citations

Heavy-chain binding protein recognizes aberrant polypeptides translocated in vitro

1988 • 219 citations

Identification, characterization, and purification of two mammalian stress proteins present in mitochondria, grp 75, a member of the hsp 70 family and hsp 58, a homolog of the bacterial groEL protein

1989 • 199 citations

Characterization of the thermotolerant cell. II. Effects on the intracellular distribution of heat-shock protein 70, intermediate filaments, and small nuclear ribonucleoprotein complexes.

1988 • 195 citations

Binding of heat shock proteins to the avian progesterone receptor.

1989 • 192 citations

Interaction of heavy chain binding protein (BiP/GRP78) with adenine nucleotides.

1989 • 176 citations

Mutational analysis of the human HSP70 protein: distinct domains for nucleolar localization and adenosine triphosphate binding.

1989 • 175 citations

Dissociation of clathrin coats coupled to the hydrolysis of ATP: role of an uncoating ATPase.

1984 • 153 citations

Primary structures of bovine elastin a, b, and c deduced from the sequences of cDNA clones.

1987 • 153 citations

Cell cycle-dependent association of HSP70 with specific cellular proteins.

1989 • 145 citations

Inhibition of heat shock (stress) protein induction by deuterium oxide and glycerol: Additional support for the abnormal protein hypothesis of induction

1989 • 143 citations

The role of stress proteins in membrane biogenesis

1988 • 133 citations

Developmental regulation of a constitutively expressed mouse mRNA encoding a 72-kDa heat shock-like protein

1988 • 119 citations

Dissociation of clathrin from coated vesicles by the uncoating ATPase.

1990 • 109 citations

Members of the 70-Kilodalton Heat Shock Protein Family Contain a Highly Conserved Calmodulin-Binding Domain

1990 • 108 citations

Purification of complexes of nuclear oncogene p53 with rat and Escherichia coli heat shock proteins: in vitro dissociation of hsc70 and dnaK from murine p53 by ATP.

1988 • 106 citations

Association of a cellular heat shock protein with simian virus 40 large T antigen in transformed cells

1989 • 99 citations

β-internexin is a microtubule-associated protein identical to the 70-kDa heat-shock cognate protein and the clathrin uncoating ATPase

1989 • 73 citations

Differential distribution of the adenovirus E1A proteins and colocalization of E1A with the 70-kilodalton cellular heat shock protein in infected cells

1988 • 66 citations

Medium tumor antigen of polyomavirus transformation-defective mutant NG59 is associated with 73-kilodalton heat shock protein

1987 • 62 citations

Two classes of binding sites for uncoating protein in clathrin triskelions.

1985 • 49 citations

Crystals of an ATPase fragment of bovine clathrin uncoating ATPase

1988 • 20 citations