Structurally similar oxidized phospholipids differentially regulate endothelial binding of monocytes and neutrophils

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

1968 • 5,084 citations

Endothelial Expression of a Mononuclear Leukocyte Adhesion Molecule During Atherogenesis

1991 • 1,703 citations

The role of oxidized lipoproteins in atherogenesis

1996 • 1,382 citations

The role of the monocyte in atherogenesis: I. Transition of blood-borne monocytes into foam cells in fatty lesions.

1981 • 1,325 citations

Phosphorylation of NF-κB p65 by PKA Stimulates Transcriptional Activity by Promoting a Novel Bivalent Interaction with the Coactivator CBP/p300

1998 • 1,200 citations

Sphingosine-1-Phosphate as a Ligand for the G Protein-Coupled Receptor EDG-1

1998 • 1,003 citations

Cell Biology of Atherosclerosis

1995 • 982 citations

Minimally modified low density lipoprotein stimulates monocyte endothelial interactions.

1990 • 930 citations

Lysophosphatidylcholine, a component of atherogenic lipoproteins, induces mononuclear leukocyte adhesion molecules in cultured human and rabbit arterial endothelial cells.

1992 • 828 citations

The Transcriptional Activity of NF-κB Is Regulated by the IκB-Associated PKAc Subunit through a Cyclic AMP–Independent Mechanism

1997 • 820 citations

Structural Identification by Mass Spectrometry of Oxidized Phospholipids in Minimally Oxidized Low Density Lipoprotein That Induce Monocyte/Endothelial Interactions and Evidence for Their Presence in Vivo

1997 • 751 citations

Cloning by functional expression of platelet-activating factor receptor from guinea-pig lung

1991 • 594 citations

Neovascular Expression of E-Selectin, Intercellular Adhesion Molecule-1, and Vascular Cell Adhesion Molecule-1 in Human Atherosclerosis and Their Relation to Intimal Leukocyte Content

1996 • 573 citations

Monoclonal autoantibodies specific for oxidized phospholipids or oxidized phospholipid–protein adducts inhibit macrophage uptake of oxidized low-density lipoproteins

1999 • 552 citations

Effect of platelet activating factor-acetylhydrolase on the formation and action of minimally oxidized low density lipoprotein.

1995 • 412 citations

Cloning and expression of a cDNA for the human prostanoid FP receptor.

1994 • 386 citations

[16] Electrophysiologic recordings from Xenopus oocytes

1998 • 361 citations

Antiphospholipid antibodies are directed against epitopes of oxidized phospholipids. Recognition of cardiolipin by monoclonal antibodies to epitopes of oxidized low density lipoprotein.

1996 • 354 citations

Elevated Cyclic AMP Inhibits NF-κB-mediated Transcription in Human Monocytic Cells and Endothelial Cells

1996 • 341 citations

Role of cyclic AMP response element-binding protein in cyclic AMP inhibition of NF-kappaB-mediated transcription.

1997 • 320 citations

Minimally modified low density lipoprotein-induced inflammatory responses in endothelial cells are mediated by cyclic adenosine monophosphate.

1993 • 251 citations

[19] Electrophysiological recording from Xenopus oocytes

1992 • 236 citations

Molecular Cloning of the Human Edg2 Protein and Its Identification as a Functional Cellular Receptor for Lysophosphatidic Acid

1997 • 232 citations

Elevated cyclic AMP inhibits endothelial cell synthesis and expression of TNF-induced endothelial leukocyte adhesion molecule-1, and vascular cell adhesion molecule-1, but not intercellular adhesion molecule-1.

1993 • 192 citations

Cloning and expression of a cDNA for the human prostanoid IP receptor.

1994 • 187 citations

Cooperativity between two NF-kappa B complexes, mediated by high-mobility-group protein I(Y), is essential for cytokine-induced expression of the E-selectin promoter.

1994 • 159 citations

Minimally modified low-density lipoprotein induces monocyte adhesion to endothelial connecting segment-1 by activating β1 integrin

1999 • 150 citations

Role of Group II Secretory Phospholipase A ₂ in Atherosclerosis

1999 • 149 citations

Effects of defolliculation on membrane current responses of Xenopus oocytes.

1989 • 147 citations

The epitopes for some antiphospholipid antibodies are adducts of oxidized phospholipid and β₂glycoprotein 1 (and other proteins)

1997 • 142 citations

Glucocorticoids inhibit E-selectin expression by targeting NF-kappaB and not ATF/c-Jun.

1997 • 140 citations

Alterations in Individual Molecular Species of Human Platelet Phospholipids during Thrombin Stimulation: Electrospray Ionization Mass Spectrometry-Facilitated Identification of the Boundary Conditions for the Magnitude and Selectivity of Thrombin-Induced Platelet Phospholipid Hydrolysis

1996 • 137 citations

Oxidized Lipids in Atherogenesis: Formation, Destruction and Action

1997 • 136 citations

bcl-2 expression decreases methyl mercury-induced free-radical generation and cell killing in a neural cell line

1994 • 133 citations

Identification of a protein that confers calcitonin gene-related peptide responsiveness to oocytes by using a cystic fibrosis transmembrane conductance regulator assay.

1996 • 121 citations

Modification of the Recalde method for the isolation of human monocytes.

1988 • 114 citations

cAMP and tumor necrosis factor competitively regulate transcriptional activation through and nuclear factor binding to the cAMP-responsive element/activating transcription factor element of the endothelial leukocyte adhesion molecule-1 (E-selectin) promoter.

1994 • 79 citations

Determination of lipid ester ozonides and core aldehydes by high-performance liquid chromatography with on-line mass spectrometry

1995 • 72 citations

Action of cAMP on expression and release of adhesion molecules in human endothelial cells

1996 • 68 citations

N-palmitoyl-serine and N-palmitoyl-tyrosine phosphoric acids are selective competitive antagonists of the lysophosphatidic acid receptors.

1996 • 57 citations

Stimulation of G_sand Inhibition of G_iProtein Functions by Minimally Oxidized LDL

1995 • 52 citations

Cooperativity between Two NF-κΒ Complexes, Mediated by High-Mobility-Group Protein I(Y), Is Essential for Cytokine-Induced Expression of the E-Selectin Promoter

1994 • 48 citations

Transcription factor-induced, phased bending of the E-selectin promoter.

1994 • 31 citations

A rapid nuclear runoff transcription assay.

1993 • 27 citations

Involvement of the tyrosinase gene in the deposition of cardiac lipofuscin in mice. Association with aortic fatty streak development.

1993 • 21 citations