Oxidized Lipids in Atherogenesis: Formation, Destruction and Action

Role of oxidized low density lipoprotein in atherogenesis.

1991 • 2,691 citations

Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS)

1996 • 2,163 citations

Hypercholesterolemia increases endothelial superoxide anion production.

1993 • 1,799 citations

Atherosclerosis: Basic Mechanisms

1995 • 1,697 citations

The role of oxidized lipoproteins in atherogenesis

1996 • 1,382 citations

CD36 is a receptor for oxidized low density lipoprotein

1993 • 1,271 citations

Paraoxonase prevents accumulation of lipoperoxides in low‐density lipoprotein

1991 • 982 citations

The Yin and Yang of Oxidation in the Development of the Fatty Streak

1996 • 705 citations

Modified low density lipoprotein and its constituents augment cytokine-activated vascular cell adhesion molecule-1 gene expression in human vascular endothelial cells.

1995 • 461 citations

Cross-regulatory roles of interleukin (IL)-12 and IL-10 in atherosclerosis.

1996 • 428 citations

Effect of platelet activating factor-acetylhydrolase on the formation and action of minimally oxidized low density lipoprotein.

1995 • 412 citations

Effect of Immunization With Homologous LDL and Oxidized LDL on Early Atherosclerosis in Hypercholesterolemic Rabbits

1996 • 355 citations

Genetic control of inflammatory gene induction and NF-kappa B-like transcription factor activation in response to an atherogenic diet in mice.

1993 • 291 citations

Role of oxidized low density lipoprotein in atherogenesis

1992 • 279 citations

Minimally modified low density lipoprotein-induced inflammatory responses in endothelial cells are mediated by cyclic adenosine monophosphate.

1993 • 251 citations

Genetic evidence for a common pathway mediating oxidative stress, inflammatory gene induction, and aortic fatty streak formation in mice.

1994 • 228 citations

Minimally oxidized low-density lipoprotein induces tissue factor expression in cultured human endothelial cells.

1991 • 228 citations

Cytotoxicity of oxidized LDL to porcine aortic smooth muscle cells is associated with the oxysterols 7-ketocholesterol and 7-hydroxycholesterol.

1994 • 190 citations

Oxidized low density lipoprotein inhibits the migration of aortic endothelial cells in vitro.

1993 • 115 citations

Roles of multiple oxidized LDL lipids in cellular injury: dominance of 7 beta-hydroperoxycholesterol

1996 • 100 citations

Toxicity of oxidised low density lipoprotein towards mouse peritoneal macrophages in vitro

1993 • 95 citations

Lowering of HDL _2b by Probucol Partly Explains the Failure of the Drug to Affect Femoral Atherosclerosis in Subjects With Hypercholesterolemia

1995 • 81 citations

Lipid-induced changes in intracellular iron homeostasis in vitro and in vivo.

1995 • 76 citations

Atheromatous plaque macrophages produce plasminogen activator inhibitor type-1 and stimulate its production by endothelial cells and vascular smooth muscle cells.

1993 • 56 citations

PAF-acether-degrading acetylhydrolase in plasma LDL is inactivated by copper- and cell-mediated oxidation.

1994 • 52 citations