Infection and multiple sclerosis: a possible role for superantigens?

The Staphylococcal Enterotoxins and Their Relatives

1990 • 1,914 citations

Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen

1992 • 1,200 citations

The Vβ-specific superantigen staphylococcal enterotoxin B: Stimulation of mature T cells and clonal deletion in neonatal mice

1989 • 1,095 citations

Amino Acid Homology Between the Encephalitogenic Site of Myelin Basic Protein and Virus: Mechanism for Autoimmunity

1985 • 941 citations

Limited heterogeneity of T cell receptors from lymphocytes mediating autoimmune encephalomyelitis allows specific immune intervention

1988 • 940 citations

Blood-Brain Barrier in Physiology and Medicine

1976 • 888 citations

Evidence for the Effects of a Superantigen in Rheumatoid Arthritis

1991 • 632 citations

Superantigens and Their Potential Role in Human Disease

1993 • 620 citations

Restricted use of T cell receptor V genes in murine autoimmune encephalomyelitis raises possibilities for antibody therapy

1988 • 555 citations

Superantigens interact with MHC class II molecules outside of the antigen groove

1990 • 438 citations

Measles Encephalomyelitis — Clinical and Immunologic Studies

1984 • 404 citations

Selection for T-cell receptor Vβ–Dβ–Jβ gene rearrangements with specificity for a myelin basic protein peptide in brain lesions of multiple sclerosis

1993 • 400 citations

The cognitive paradigm and the immunological homunculus

1992 • 375 citations

Induction of relapsing paralysis in experimental autoimmune encephalomyelitis by bacterial superantigen

1993 • 260 citations

Sequence Homology Between Certain Viral Proteins and Proteins Related to Encephalomyelitis and Neuritis

1985 • 243 citations

The cognitive principle challenges clonal selection

1992 • 212 citations

T-cell recognition of myelin basic protein

1991 • 134 citations

SEB induced anergy: modulation of immune response to T cell determinants of myoglobin and myelin basic protein.

1993 • 30 citations

Simultaneous visualization of vascular permeability change and leukocyte egress in the central nervous system during autoimmune encephalomyelitis

1987 • 24 citations

Heat-killed Listeria monocytogenes and L. monocytogenes soluble antigen induce clonable CD4+ T lymphocytes with protective and chemotactic activities in vivo

1991 • 20 citations

The Epigenetics of Multiple Sclerosis: Clues to Etiology and a Rationale for Immune Therapy

1994 • 18 citations