ERCC1/XPF Removes the 3′ Overhang from Uncapped Telomeres and Represses Formation of Telomeric DNA-Containing Double Minute Chromosomes

Genome maintenance mechanisms for preventing cancer

2001 • 3,819 citations

Mammalian Telomeres End in a Large Duplex Loop

1999 • 2,372 citations

Femtomole sequencing of proteins from polyacrylamide gels by nano-electrospray mass spectrometry

1996 • 1,687 citations

TRF2 Protects Human Telomeres from End-to-End Fusions

1998 • 1,679 citations

DNA Damage Foci at Dysfunctional Telomeres

2003 • 1,341 citations

Control of telomere length by the human telomeric protein TRF1

1997 • 1,197 citations

Molecular mechanism of nucleotide excision repair

1999 • 1,118 citations

p53- and ATM-Dependent Apoptosis Induced by Telomeres Lacking TRF2

1999 • 1,076 citations

Protection of mammalian telomeres

2002 • 926 citations

Human telomeres contain two distinct Myb–related proteins, TRF1 and TRF2

1997 • 913 citations

Long G Tails at Both Ends of Human Chromosomes Suggest a C Strand Degradation Mechanism for Telomere Shortening

1997 • 897 citations

Heterogeneity in telomere length of human chromosomes

1996 • 861 citations

Mammalian DNA nucleotide excision repair reconstituted with purified protein components

1995 • 833 citations

Senescence Induced by Altered Telomere State, Not Telomere Loss

2002 • 787 citations

A Human Telomeric Protein

1995 • 689 citations

Distribution of non-telomeric sites of the (TTAGGG)n telomeric sequence in vertebrate chromosomes

1990 • 614 citations

Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres

2000 • 600 citations

Xeroderma Pigmentosum Group F Caused by a Defect in a Structure-Specific DNA Repair Endonuclease

1996 • 537 citations

Extensive allelic variation and ultrashort telomeres in senescent human cells

2003 • 528 citations

T-loop assembly in vitro involves binding of TRF2 near the 3' telomeric overhang

2001 • 521 citations

Telomeric localization of TRF2, a novel human telobox protein

1997 • 495 citations

Different telomere damage signaling pathways in human and mouse cells

2002 • 475 citations

Increased susceptibility to ultraviolet-B and carcinogens of mice lacking the DNA excision repair gene XPA

1995 • 406 citations

Removal of Nonhomologous DNA Ends in Double-Strand Break Recombination: the Role of the Yeast Ultraviolet Repair Gene RAD1

1992 • 375 citations

DNA Ligase IV-Dependent NHEJ of Deprotected Mammalian Telomeres in G1 and G2

2002 • 370 citations

Disruption of mouse ERCC1 results in a novel repair syndrome with growth failure, nuclear abnormalities and senescence

1997 • 368 citations

Base Sequence and Evolution of Guinea-pig α-Satellite DNA

1970 • 357 citations

Action of DNA Repair Endonuclease ERCC1/XPF in Living Cells

1999 • 351 citations

Erosion of the telomeric single-strand overhang at replicative senescence

2003 • 332 citations

DNA-binding polarity of human replication protein A positions nucleases in nucleotide excision repair

1998 • 327 citations

Mice with DNA repair gene (ERCC-1) deficiency have elevated levels of p53, liver nuclear abnormalities and die before weaning

1993 • 322 citations

Fluorescence in situ hybridization

1993 • 308 citations

High incidence of ultraviolet-B-or chemical-carcinogen-induced skin tumours in mice lacking the xeroderma pigmentosum group A gene

1995 • 292 citations

Strand-Specific Postreplicative Processing of Mammalian Telomeres

2001 • 259 citations

High susceptibility to ultraviolet-induced carcinogenesis in mice lacking XPC

1995 • 252 citations

DNA Structural Elements Required for ERCC1-XPF Endonuclease Activity

1998 • 225 citations

RAD1 and RAD10, but Not Other Excision Repair Genes, Are Required for Double-Strand Break-Induced Recombination in Saccharomyces cerevisiae

1995 • 217 citations

RAD1, an excision repair gene of Saccharomyces cerevisiae, is also involved in recombination.

1988 • 209 citations

Formation of a ternary complex by human XPA, ERCC1, and ERCC4(XPF) excision repair proteins.

1994 • 186 citations

Evidence for a repair enzyme complex involving ERCC1 and complementing activities of ERCC4, ERCC11 and xeroderma pigmentosum group F.

1993 • 185 citations

Co-correction of the ERCC1, ERCC4 and xeroderma pigmentosum group F DNA repair defects in vitro.

1993 • 171 citations

The structure-specific endonuclease Ercc1-Xpf is required for targeted gene replacement in embryonic stem cells

2001 • 160 citations

Role of ERCC1 in removal of long non-homologous tails during targeted homologous recombination

2000 • 122 citations

ERCC4 (XPF) Encodes a Human Nucleotide Excision Repair Protein with Eukaryotic Recombination Homologs

1996 • 118 citations

Role of the nucleotide excision repair gene ERCC1 in formation of recombination-dependent rearrangements in mammalian cells

2000 • 112 citations

Molecular biology of double‐minute chromosomes

1993 • 104 citations

G-strand overhangs on telomeres in telomerase-deficient mouse cells

1999 • 93 citations

Fluorescence in situ hybridization with a synthetic (T<sub>2</sub>AG<sub>3</sub>)<sub>n</sub> polynucleotide detects several intrachromosomal telomere-like repeats on human chromosomes

1997 • 76 citations

A low content of ERCC1 and a 120 kDa protein is a frequent feature of group F xeroderma pigmentosum fibroblast cells

1997 • 46 citations

Origin and evolution of a major feline satellite DNA

1987 • 46 citations

Late onset of skin cancers in 2 xeroderma pigmentosum group F siblings and a review of 30 Japanese xeroderma pigmentosum patients in groups D, E and F.

1989 • 36 citations

Apparent lack of telomere sequences on double minute chromosomes

1990 • 21 citations