Molecular mechanism of nucleotide excision repair

The Metabolic Basis of Inherited Disease.

1988 • 7,933 citations

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

1994 • 1,669 citations

REPLICATION PROTEIN A: A Heterotrimeric, Single-Stranded DNA-Binding Protein Required for Eukaryotic DNA Metabolism

1997 • 1,417 citations

Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene

1987 • 1,235 citations

DNA EXCISION REPAIR

1996 • 1,127 citations

Xeroderma Pigmentosum Group C Protein Complex Is the Initiator of Global Genome Nucleotide Excision Repair

1998 • 872 citations

Mammalian DNA nucleotide excision repair reconstituted with purified protein components

1995 • 833 citations

Proliferating cell nuclear antigen is required for DNA excision repair

1992 • 809 citations

DNA Repair Helicase: a Component of BTF2 (TFIIH) Basic Transcription Factor

1993 • 795 citations

Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1)

1997 • 779 citations

DNA REPAIR IN EUKARYOTES

1996 • 682 citations

Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair

1994 • 657 citations

THE BIOLOGY OF THE (6–4) PHOTOPRODUCT

1989 • 604 citations

Induction of the Escherichia coli lactose operon selectively increases repair of its transcribed DNA strand

1989 • 576 citations

Expression of the p48 xeroderma pigmentosum gene is p53-dependent and is involved in global genomic repair

1999 • 571 citations

Structure of the single-stranded-DNA-binding domain of replication protein A bound to DNA

1997 • 557 citations

The genetic defect in Cockayne syndrome is associated with a defect in repair of UV-induced DNA damage in transcriptionally active DNA.

1990 • 552 citations

Xeroderma Pigmentosum Group F Caused by a Defect in a Structure-Specific DNA Repair Endonuclease

1996 • 537 citations

Purification and characterization of replication protein A, a cellular protein required for in vitro replication of simian virus 40 DNA.

1988 • 495 citations

Mechanism of open complex and dual incision formation by human nucleotide excision repair factors

1997 • 494 citations

The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH

1995 • 485 citations

XPG endonuclease makes the 3′ incision in human DNA nucleotide excision repair

1994 • 481 citations

Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase II

1994 • 473 citations

Reconstitution of Human DNA Repair Excision Nuclease in a Highly Defined System

1995 • 460 citations

Nucleotide Excision Repair in Mammalian Cells

1997 • 446 citations

The FEN‐1 family of structure‐specific nucleases in eukaryotic dna replication, recombination and repair

1997 • 434 citations

The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor

1994 • 432 citations

Cdk-activating kinase complex is a component of human transcription factor TFIIH

1995 • 431 citations

Human nucleotide excision nuclease removes thymine dimers from DNA by incising the 22nd phosphodiester bond 5' and the 6th phosphodiester bond 3' to the photodimer.

1992 • 428 citations

Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK

1994 • 426 citations

Xeroderma Pigmentosum Group E Cells Lack a Nuclear Factor That Binds to Damaged DNA

1988 • 417 citations

Reconstitution of complete SV40 DNA replication with purified replication factors.

1994 • 403 citations

Cellular factors required for multiple stages of SV40 DNA replication in vitro.

1988 • 398 citations

Analysis of a human DNA excision repair gene involved in group A xeroderma pigmentosum and containing a zinc-finger domain

1990 • 395 citations

Purification and cloning of a nucleotide excision repair complex involving the xeroderma pigmentosum group C protein and a human homologue of yeast RAD23.

1994 • 394 citations

RPA involvement in the damage-recognition and incision steps of nucleotide excision repair

1995 • 387 citations

The ERCC2/DNA repair protein is associated with the class II BTF2/TFIIH transcription factor.

1994 • 381 citations

Removal of Nonhomologous DNA Ends in Double-Strand Break Recombination: the Role of the Yeast Ultraviolet Repair Gene RAD1

1992 • 375 citations

Association of Cdk-activating kinase subunits with transcription factor TFIIH

1995 • 366 citations

Expression of Wild-type p53 Is Required for Efficient Global Genomic Nucleotide Excision Repair in UV-irradiated Human Fibroblasts

1997 • 365 citations

Reaction Mechanism of Human DNA Repair Excision Nuclease

1996 • 362 citations

The helix-hairpin-helix DNA-binding motif: a structural basis for non- sequence-specific recognition of DNA

1996 • 362 citations

In vitro repair of oxidative DNA damage by human nucleotide excision repair system: Possible explanation for neurodegeneration in Xeroderma pigmentosum patients

1997 • 358 citations

Transcript cleavage by RNA polymerase II arrested by a cyclobutane pyrimidine dimer in the DNA template.

1994 • 357 citations

Replication of simian virus 40 origin-containing DNA in vitro with purified proteins.

1987 • 355 citations

Molecular characterization of the human excision repair gene : cDNA cloning and amino acid homology with the yeast DNA repair gene

1986 • 330 citations

DNA-binding polarity of human replication protein A positions nucleases in nucleotide excision repair

1998 • 327 citations

Cell-cycle-regulated phosphorylation of DNA replication factor A from human and yeast cells.

1990 • 327 citations

Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair

1993 • 317 citations

Xeroderma pigmentosum complementation group C cells remove pyrimidine dimers selectively from the transcribed strand of active genes.

1991 • 313 citations

Defective Transcription-Coupled Repair of Oxidative Base Damage in Cockayne Syndrome Patients from XP Group G

1997 • 307 citations

Role of Saccharomyces cerevisiae Msh2 and Msh3 repair proteins in double-strand break-induced recombination

1997 • 305 citations

Specific association between the human DNA repair proteins XPA and ERCC1.

1994 • 304 citations

Factors Involved in Specific Transcription by Mammalian RNA Polymerase II

1989 • 304 citations

Preferential binding of the xeroderma pigmentosum group A complementing protein to damaged DNA

1993 • 295 citations

Deficient repair of the transcribed strand of active genes in Cockayne's syndrome cells

1993 • 292 citations

Binding properties of replication protein A from human and yeast cells.

1992 • 292 citations

Transcription-Coupled Repair Deficiency and Mutations in Human Mismatch Repair Genes

1996 • 289 citations

Mutations in the DNA ligase I gene of an individual with immunodeficiencies and cellular hypersensitivity to DNA-damaging agents

1992 • 283 citations

Different forms of TFIIH for transcription and DNA repair: Holo-TFIIH and a nucleotide excision repairosome

1995 • 280 citations

Nucleotide Excision Repair DNA Synthesis by DNA Polymerase .epsilon. in the Presence of PCNA, RFC, and RPA

1995 • 275 citations

An Interaction between the DNA Repair Factor XPA and Replication Protein A Appears Essential for Nucleotide Excision Repair

1995 • 257 citations

Human Transcription-Repair Coupling Factor CSB/ERCC6 Is a DNA-stimulated ATPase but Is Not a Helicase and Does Not Disrupt the Ternary Transcription Complex of Stalled RNA Polymerase II

1997 • 255 citations

The role of human single-stranded DNA binding protein and its individual subunits in simian virus 40 DNA replication.

1990 • 254 citations

Interactions of human replication protein A with oligonucleotides

1994 • 248 citations

Proliferating cell nuclear antigen: More than a clamp for DNA polymerases

1997 • 248 citations

The Saccharomyces cerevisiae DNA repair gene RAD23 encodes a nuclear protein containing a ubiquitin-like domain required for biological function.

1993 • 246 citations

DNA repair synthesis in human fibroblasts requires DNA polymerase delta.

1988 • 245 citations

Transcription-coupled repair removes both cyclobutane pyrimidine dimers and 6-4 photoproducts with equal efficiency and in a sequential way from transcribed DNA in xeroderma pigmentosum group C fibroblasts.

1995 • 244 citations

The Cockayne syndrome B protein, involved in transcription-coupled DNA repair, resides in an RNA polymerase II-containing complex

1997 • 244 citations

Opening of an RNA polymerase II promoter occurs in two distinct steps and requires the basal transcription factors IIE and IIH.

1996 • 238 citations

Identification of cellular proteins required for simian virus 40 DNA replication

1989 • 238 citations

The DNA Repair Endonuclease XPG Binds to Proliferating Cell Nuclear Antigen (PCNA) and Shares Sequence Elements with the PCNA-binding Regions of FEN-1 and Cyclin-dependent Kinase Inhibitor p21

1997 • 236 citations

RELATIONSHIPS BETWEEN DNA REPAIR AND TRANSCRIPTION

1996 • 235 citations

Open complex formation around a lesion during nucleotide excision repair provides a structure for cleavage by human XPG protein

1997 • 233 citations

The residual repair capacity of xeroderma pigmentosum complementation group C fibroblasts is highly specific for transcriptionally active DNA

1990 • 231 citations

Requirement for the replication protein SSB in human DMA excision repair

1991 • 227 citations

DNA Structural Elements Required for ERCC1-XPF Endonuclease Activity

1998 • 225 citations

Human DNA Repair Excision Nuclease

1995 • 216 citations

Preferential repair of ionizing radiation-induced damage in the transcribed strand of an active human gene is defective in Cockayne syndrome.

1993 • 215 citations

Multiple functions of human single-stranded-DNA binding protein in simian virus 40 DNA replication: single-strand stabilization and stimulation of DNA polymerases alpha and delta.

1989 • 214 citations

Two Pathways for Removal of Nonhomologous DNA Ends during Double-Strand Break Repair in Saccharomyces cerevisiae

1997 • 212 citations

Characterization of a human DNA damage binding protein implicated in xeroderma pigmentosum E.

1993 • 208 citations

Comparative analysis of binding of human damaged DNA-binding protein (XPE) and Escherichia coli damage recognition protein (UvrA) to the major ultraviolet photoproducts: T[c,s]T, T[t,s]T, T[6-4]T, and T[Dewar]T.

1993 • 208 citations

Analysis of Incision Sites Produced by Human Cell Extracts and Purified Proteins during Nucleotide Excision Repair of a 1,3-Intrastrand d(GpTpG)-Cisplatin Adduct

1996 • 205 citations

Synthesis of DNA by DNA polymerase epsilon in vitro.

1991 • 204 citations

Complementation of the DNA repair defect in xeroderma pigmentosum group G cells by a human cDNA related to yeast RAD2

1993 • 203 citations

The ionizing radiation-induced replication protein A phosphorylation response differs between ataxia telangiectasia and normal human cells.

1993 • 203 citations

Purification and interaction properties of the human RNA polymerase B(II) general transcription factor BTF2.

1991 • 202 citations

Complementation of DNA repair in xeroderma pigmentosum group A cell extracts by a protein with affinity for damaged DNA.

1991 • 200 citations

The RAD7 and RAD16 genes, which are essential for pyrimidine dimer removal from the silent mating type loci, are also required for repair of the nontranscribed strand of an active gene in Saccharomyces cerevisiae.

1994 • 200 citations

Processing of branched DNA intermediates by a complex of human FEN-1 and PCNA

1996 • 200 citations

Substrate specificity of the cdk-activating kinase (CAK) is altered upon association with TFIIH

1997 • 195 citations

Mutant rodent cell lines sensitive to ultraviolet light, ionizing radiation and cross-linking agents: a comprehensive survey of genetic and biochemical characteristics

1993 • 193 citations

Interactions Involving the Human RNA Polymerase II Transcription/Nucleotide Excision Repair Complex TFIIH, the Nucleotide Excision Repair Protein XPG, and Cockayne Syndrome Group B (CSB) Protein

1996 • 193 citations

Recruitment of the Putative Transcription-Repair Coupling Factor CSB/ERCC6 to RNA Polymerase II Elongation Complexes

1997 • 191 citations

The General Transcription-Repair Factor TFIIH Is Recruited to the Excision Repair Complex by the XPA Protein Independent of the TFIIE Transcription Factor

1995 • 188 citations

Replication Protein A Confers Structure-specific Endonuclease Activities to the XPF-ERCC1 and XPG Subunits of Human DNA Repair Excision Nuclease

1996 • 187 citations

Formation of a ternary complex by human XPA, ERCC1, and ERCC4(XPF) excision repair proteins.

1994 • 186 citations

UV light-induced DNA synthesis arrest in HeLa cells is associated with changes in phosphorylation of human single-stranded DNA-binding protein.

1994 • 186 citations

Evidence for a repair enzyme complex involving ERCC1 and complementing activities of ERCC4, ERCC11 and xeroderma pigmentosum group F.

1993 • 185 citations

Characterization of DNA-binding and strand-exchange stimulation properties of y-RPA, a yeast single-strand-DNA-binding protein

1992 • 184 citations

Three transitions in the RNA polymerase II transcription complex during initiation

1997 • 181 citations

Co-correction of the ERCC1, ERCC4 and xeroderma pigmentosum group F DNA repair defects in vitro.

1993 • 171 citations

Assembly, subunit composition, and footprint of human DNA repair excision nuclease

1998 • 169 citations

Reconstitution of Human Excision Nuclease with Recombinant XPF-ERCC1 Complex

1997 • 168 citations

Which DNA polymerases are used for DNA-repair in eukaryotes?

1997 • 166 citations

Overproduction, Purification, and Characterization of the XPC Subunit of the Human DNA Repair Excision Nuclease

1996 • 165 citations

A common mutational pattern in Cockayne syndrome patients from xeroderma pigmentosum group G: Implications for a second XPG function

1997 • 165 citations

HHR23B, a Human Rad23 Homolog, Stimulates XPC Protein in Nucleotide Excision Repair In Vitro

1996 • 164 citations

Transcription factor b (TFIIH) is required during nucleotide-excision repair in yeast

1994 • 163 citations

Characterization of Reaction Intermediates of Human Excision Repair Nuclease

1997 • 162 citations

The Non-catalytic Function of XPG Protein during Dual Incision in Human Nucleotide Excision Repair

1997 • 158 citations

The XPA protein is a zinc metalloprotein with an ability to recognize various kinds of DNA damage

1994 • 155 citations

Mutations Specific to the Xeroderma Pigmentosum Group E Ddb− Phenotype

1996 • 151 citations

Aberrant DNA repair and DNA replication due to an inherited enzymatic defect in human DNA ligase I.

1994 • 147 citations

A role for the human single-Stranded DNA binding protein HSSB/RPA in an early stage of nucleotide excision repair

1992 • 145 citations

Three Unusual Repair Deficiencies Associated with Transcription Factor BTF2(TFIIH): Evidence for the Existence of a Transcription Syndrome

1994 • 144 citations

Nucleosome structure and positioning modulate nucleotide excision repair in the non-transcribed strand of an active gene

1997 • 143 citations

The requirement for the basal transcription factor IIE is determined by the helical stability of promoter DNA.

1995 • 143 citations

Solution structure of the DNA- and RPA-binding domain of the human repair factor XPA

1998 • 141 citations

Mutations in XPA That Prevent Association with ERCC1 Are Defective in Nucleotide Excision Repair

1995 • 137 citations

Distinct roles of cdk2 and cdc2 in RP-A phosphorylation during the cell cycle

1993 • 136 citations

Strand-selective repair of DNA damage in the yeast GAL7 gene requires RNA polymerase II

1992 • 134 citations

Human Replication Protein A Binds Single-Stranded DNA in Two Distinct Complexes

1994 • 133 citations

Human nucleotide excision repair syndromes: Molecular clues to unexpected intricacies

1994 • 130 citations

Purification and Characterization of the XPF-ERCC1 Complex of Human DNA Repair Excision Nuclease

1995 • 129 citations

Two Human Homologs of Rad23 Are Functionally Interchangeable in Complex Formation and Stimulation of XPC Repair Activity

1997 • 129 citations

An RNA polymerase II transcription factor has an associated DNA-dependent ATPase (dATPase) activity strongly stimulated by the TATA region of promoters.

1989 • 127 citations

A role for TFIIH in controlling the activity of early RNA polymerase II elongation complexes

1997 • 127 citations

Replication factor A is required in vivo for DNA replication, repair, and recombination.

1994 • 125 citations

Single-Stranded-DNA Binding Alters Human Replication Protein A Structure and Facilitates Interaction with DNA-Dependent Protein Kinase

1996 • 123 citations

Correction of the DNA repair defect in xeroderma pigmentosum group E by injection of a DNA damage-binding protein.

1994 • 123 citations

Identical defects in DNA repair in xeroderma pigmentosum group G and rodent ERCC group 5

1993 • 122 citations

Physical interaction between components of DNA mismatch repair and nucleotide excision repair

1998 • 121 citations

Cloning of the 62-Kilodalton Component of Basic Transcription Factor BTF2

1992 • 120 citations

A hierarchy of SSB protomers in replication protein A.

1996 • 120 citations

Isolation and characterization of two human transcription factor IIH (TFIIH)-related complexes: ERCC2/CAK and TFIIH.

1996 • 119 citations

Mammalian DNA ligases

1997 • 119 citations

ERCC4 (XPF) Encodes a Human Nucleotide Excision Repair Protein with Eukaryotic Recombination Homologs

1996 • 118 citations

Binding Properties of Replication Protein A from Human and Yeast Cells

1992 • 118 citations

XPC and human homologs of RAD23: intracellular localization and relationship to other nucleotide excision repair complexes

1996 • 117 citations

An Affinity of Human Replication Protein A for Ultraviolet-damaged DNA

1996 • 114 citations

p44 and p34 subunits of the BTF2/TFIIH transcription factor have homologies with SSL1, a yeast protein involved in DNA repair.

1994 • 114 citations

Correction of xeroderma pigmentosum repair defect by basal transcription factor BTF2 (TFIIH).

1994 • 114 citations

Relationship of the Xeroderma Pigmentosum Group E DNA Repair Defect to the Chromatin and DNA Binding Proteins UV-DDB and Replication Protein A

1998 • 113 citations

Mapping of interaction domains between human repair proteins ERCC1 and XPF

1998 • 113 citations

The RPA32 Subunit of Human Replication Protein A Contains a Single-stranded DNA-binding Domain

1998 • 113 citations

Cockayne syndrome: defective repair of transcription?

1997 • 113 citations

Purification and characterization of a human protein that binds to damaged DNA

1993 • 112 citations

Mutational analysis of the human nucleotide excision repair gene ERCC1

1996 • 111 citations

Essential Amino Acids for Substrate Binding and Catalysis of Human Flap Endonuclease 1

1996 • 110 citations

DNA Damage Recognition by XPA Protein Promotes Efficient Recruitment of Transcription Factor II H

1997 • 108 citations

Identification of a damaged-DNA binding domain of the XPA protein

1996 • 106 citations

Stranded in an active gene

1993 • 105 citations

Functional analysis of point mutations in human flap endonuclease-1 active site

1997 • 102 citations

DNA Polymerases Required for Repair of UV-Induced Damage in Saccharomyces cerevisiae

1995 • 101 citations

Model for XPC-independent Transcription-coupled Repair of Pyrimidine Dimers in Humans

1997 • 101 citations

Identification and Characterization of XPC-Binding Domain of hHR23B

1997 • 100 citations

Sequential binding of DNA repair proteins RPA and ERCC1 to XPA in vitro

1996 • 99 citations

Double Mutants of Saccharomyces cerevisiae with Alterations in Global Genome and Transcription-Coupled Repair

1996 • 97 citations

Yeast Rad7-Rad16 Complex, Specific for the Nucleotide Excision Repair of the Nontranscribed DNA Strand, Is an ATP-dependent DNA Damage Sensor

1997 • 95 citations

Functional Domains of the 70-Kilodalton Subunit of Human Replication Protein A

1996 • 95 citations

Simian virus 40 DNA replication in vitro: identification of multiple stages of initiation.

1989 • 94 citations

Factors involved in specific transcription by mammalian RNA polymerase II

1989 • 93 citations

Summary of complementation groups of UV-sensitive CHO cell mutants isolated by large-scale screening

1989 • 92 citations

A constitutive damage-specific DNA-binding protein is synthesized at higher levels in UV-irradiated primate cells.

1990 • 92 citations

Xeroderma Pigmentosum Complementation Group C Cells Remove Pyrimidine Dimers Selectively from the Transcribed Strand of Active Genes

1991 • 92 citations

Binding of human single-stranded DNA binding protein to DNA damaged by the anticancer drug cis-diamminedichloroplatinum (II).

1992 • 91 citations

The Yeast TFB1 and SSL1 Genes, Which Encode Subunits of Transcription Factor IIH, Are Required for Nucleotide Excision Repair and RNA Polymerase II Transcription

1995 • 90 citations

DNA replication and UV-induced DNA repair synthesis in human fibroblasts are much less sensitive than DNA polymerase α to inhibition by butylphenyl-deoxyguanosine triphosphate

1986 • 90 citations

DNA repair defect in xeroderma pigmentosum group C and complementing factor from HeLa cells.

1994 • 87 citations

Reversible Protein Phosphorylation Modulates Nucleotide Excision Repair of Damaged DNA by Human Cell Extracts

1996 • 87 citations

Review

1997 • 86 citations

Biochemical heterogeneity in xeroderma pigmentosum complementation group E

1992 • 86 citations

Identification and Characterization of the Fourth Single-Stranded-DNA Binding Domain of Replication Protein A

1998 • 86 citations

UV damage-specific DNA-binding protein in xeroderma pigmentosum complementation group E

1991 • 84 citations

Yeast DNA Repair Protein RAD23 Promotes Complex Formation between Transcription Factor TFIIH and DNA Damage Recognition Factor RAD14

1995 • 83 citations

Functional Analysis of Human Replication Protein A in Nucleotide Excision Repair

1998 • 83 citations

Cancer from the outside, aging from the inside: Mouse models to study the consequences of defective nucleotide excision repair

1999 • 82 citations

Differential involvement of the human mismatch repair proteins, hMLH1 and hMSH2, in transcription-coupled repair.

1997 • 80 citations

Switching genes in Schizosaccharomyces pombe

1985 • 77 citations

Yeast nucleotide excision repair proteins Rad2 and Rad4 interact with RNA polymerase II basal transcription factor b (TFIIH).

1994 • 75 citations

Cloning and characterization of p52, the fifth subunit of the core of the transcription/DNA repair factor TFIIH

1997 • 74 citations

Human replication protein A binds single-stranded DNA in two distinct complexes.

1994 • 73 citations

Structural features of the minimal DNA binding domain (M98-F219) of human nucleotide excision repair protein XPA

1998 • 70 citations

The DNA-dependent ATPase activity associated with the class II basic transcription factor BTF2/TFIIH

1994 • 67 citations

Reconstitution of TFIIH and Requirement of Its DNA Helicase Subunits, Rad3 and Rad25, in the Incision Step of Nucleotide Excision Repair

1996 • 64 citations

Recruitment of damaged DNA to the nuclear matrix in hamster cells following ultraviolet irradiation

1996 • 63 citations

Purification and characterization of yeast RNA polymerase II transcription factor b.

1991 • 63 citations

Mutations that disable the DNA repair gene XPG in a xeroderma pigmentosum group G patient

1994 • 61 citations

Rad23 Is Required for Transcription-Coupled Repair and Efficient Overall Repair in Saccharomyces cerevisiae

1996 • 61 citations

Transitions in the coupling of transcription and nucleotide excision repair within RNA polymerase II-transcribed genes of Saccharomyces cerevisiae

1997 • 60 citations

Phosphorylated and unphosphorylated forms of human single-stranded DNA-binding protein are equally active in simian virus 40 DNA replication and in nucleotide excision repair.

1995 • 60 citations

Promoter Escape by RNA Polymerase II A ROLE FOR AN ATP COFACTOR IN SUPPRESSION OF ARREST BY POLYMERASE AT PROMOTER-PROXIMAL SITES

1996 • 60 citations

Role of the 70-kDa Subunit of Human Replication Protein A (I)

1996 • 59 citations

Structure-specific Nuclease Activity in Yeast Nucleotide Excision Repair Protein Rad2

1995 • 57 citations

Sequence-specific and Domain-specific DNA Repair in Xeroderma Pigmentosum and Cockayne Syndrome Cells

1997 • 56 citations

The Ionizing Radiation-Induced Replication Protein A Phosphorylation Response Differs between Ataxia Telangiectasia and Normal Human Cells

1993 • 55 citations

Replication Factor A Is Required In Vivo for DNA Replication, Repair, and Recombination

1994 • 55 citations

Transcription factor TFIIH and DNA endonuclease Rad2 constitute yeast nucleotide excision repair factor 3: implications for nucleotide excision repair and Cockayne syndrome.

1996 • 54 citations

Creation and Removal of Embedded Ribonucleotides in Chromosomal DNA during Mammalian Okazaki Fragment Processing

1997 • 54 citations

A Three-Step Pathway of Transcription Initiation Leading to Promoter Clearance at an Activated RNA Polymerase II Promoter

1996 • 52 citations

The protein sequence and some intron positions are conserved between the switching geneswi10ofSchizosaccharomyces pombeand the human excision repair gene ERCC1

1992 • 52 citations

A low content of ERCC1 and a 120 kDa protein is a frequent feature of group F xeroderma pigmentosum fibroblast cells

1997 • 46 citations

The roles of the eukaryotic DNA polymerases in DNA repair synthesis

1997 • 44 citations

RETRACTED: Requirement for DNA mismatch repair proteins in the transcription-coupled repair of thymine glycols in Saccharomyces cerevisiae

1998 • 44 citations

Aberrant DNA repair and DNA replication due to an inherited enzymatic defect in human DNA ligase I

1994 • 43 citations

Implications of the zinc‐finger motif found in the DNA‐binding domain of the human XPA protein

1996 • 42 citations

XPG protein has a structure-specific endonuclease activity

1995 • 42 citations

Simian Virus 40 DNA Replication In Vitro: Identification of Multiple Stages of Initiation

1989 • 40 citations

Multiple Functions of General Transcription Factors TFIIE and TFIIH in Transcription: Possible Points of Regulation by Trans-Acting Factors

1997 • 39 citations

Multiple ATP-dependent steps in RNA polymerase II promoter melting and initiation

1997 • 38 citations

Repair of plasmid and genomic DNA in arad7Δ mutant of yeast

1995 • 36 citations

Affinity Purification of Human DNA Repair/Transcription Factor TFIIH Using Epitope-tagged Xeroderma Pigmentosum B Protein

1998 • 35 citations

The C-terminal region of the Escherichia coli UvrC protein, which is homologous to the C-terminal region of the human ERCC1 protein, is involved in DNA binding and 5'-incision

1998 • 34 citations

Reaction Mechanism of Human DNA Repair Excision Nuclease

1996 • 34 citations

DNA Mismatch Repair Catalyzed by Extracts of Mitotic, Postmitotic, and Senescent Drosophila Tissues and Involvement of mei-9 Gene Function for Full Activity

1998 • 31 citations

Phenotypic heterogeneity in nucleotide excision repair mutants of rodent complementation groups 1 and 4

1997 • 29 citations

DNA polymerase delta mediates excision repair in growing cells damaged with ultraviolet radiation

1991 • 27 citations

In vitro repair of oxidative DNA damage by human nucleotide excision repair system: Possible explanation for neurodegeneration in Xeroderma pigmentosum patients

1997 • 26 citations

Reconstitution of Human DNA Repair Excision Nuclease in a Highly Defined System

1995 • 25 citations

Complementation of the DNA repair-deficient swi10 mutant of fission yeast by the human ERCC1 gene

1997 • 19 citations

The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor

1995 • 18 citations

The General Transcription-Repair Factor TFIIH Is Recruited to the Excision Repair Complex by the XPA Protein Independent of the TFIIE Transcription Factor

1995 • 17 citations

Relationships Between DNA Repair and Transcription

1996 • 16 citations

Characterization of Reaction Intermediates of Human Excision Repair Nuclease

1997 • 15 citations

Human DNA Repair Excision Nuclease: ANALYSIS OF THE ROLES OF THE SUBUNITS INVOLVED IN DUAL INCISIONS BY USING ANTI-XPG AND ANTI-ERCC1 ANTIBODIES

1995 • 13 citations

Formation of a ternary complex by human XPA, ERCC1, and ERCC4(XPF) excision repair proteins.

1994 • 12 citations

A common mutational pattern in Cockayne syndrome patients from xeroderma pigmentosum group G: Implications for a second XPG function

1997 • 12 citations

Yeast Nucleotide Excision Repair Proteins Rad2 and Rad4 Interact with RNA Polymerase II Basal Transcription Factor b (TFIIH)

1994 • 11 citations

Replication Protein A Confers Structure-specific Endonuclease Activities to the XPF-ERCC1 and XPG Subunits of Human DNA Repair Excision Nuclease

1996 • 10 citations

A Constitutive Damage-Specific DNA-Binding Protein Is Synthesized at Higher Levels in UV-Irradiated Primate Cells

1990 • 10 citations

Reconstitution of Human Excision Nuclease with Recombinant XPF-ERCC1 Complex

1997 • 8 citations

Model for XPC-independent Transcription-coupled Repair of Pyrimidine Dimers in Humans

1997 • 8 citations

ERCC4 (XPF) encodes a human nucleotide excision repair protein with eukaryotic recombination homologs.

1996 • 8 citations

Human Nucleotide Excision Repair Protein XPA:¹H NMR and CD Solution Studies of a Synthetic Peptide Fragment Corresponding to the Zinc-Binding Domain (101–141)

1997 • 5 citations

Isolation and characterization of two human transcription factor IIH (TFIIH)-related complexes: ERCC2/CAK and TFIIH.

1996 • 5 citations

Purification and Characterization of the XPF-ERCC1 Complex of Human DNA Repair Excision Nuclease

1995 • 5 citations

Phosphorylated and unphosphorylated forms of human single-stranded DNA-binding protein are equally active in simian virus 40 DNA replication and in nucleotide excision repair.

1995 • 3 citations

Deleted Work

1955 • 0 citations