Heat shock protein 70 binding inhibits the nuclear import of apoptosis-inducing factor

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

1997 • 7,177 citations

Molecular characterization of mitochondrial apoptosis-inducing factor

1999 • 4,031 citations

Mitochondrial control of cell death

2000 • 3,098 citations

Programmed Cell Death in Animal Development

1997 • 2,690 citations

Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome

2000 • 1,484 citations

Organelle-specific initiation of cell death pathways

2001 • 1,454 citations

Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death

2001 • 1,327 citations

Interaction of Hsp 70 with Newly Synthesized Proteins: Implications for Protein Folding and Assembly

1990 • 1,293 citations

Heat-shock protein 70 antagonizes apoptosis-inducing factor

2001 • 846 citations

Heat Shock Proteins: Endogenous Modulators of Apoptotic Cell Death

2001 • 781 citations

Mitochondrio‐nuclear translocation of AIF in apoptosis and necrosis

2000 • 778 citations

The Permeability Transition Pore Complex: A Target for Apoptosis Regulation by Caspases and Bcl-2–related Proteins

1998 • 700 citations

HSP27 inhibits cytochrome c‐dependent activation of procaspase‐9

1999 • 496 citations

Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis

1999 • 449 citations

Selective depletion of heat shock protein 70 (Hsp70) activates a tumor-specific death program that is independent of caspases and bypasses Bcl-2

2000 • 393 citations

NADH Oxidase Activity of Mitochondrial Apoptosis-inducing Factor

2001 • 382 citations

70-kD heat shock-related protein is one of at least two distinct cytosolic factors stimulating protein import into mitochondria.

1988 • 380 citations

Mechanisms of AIF-Mediated Apoptotic DNA Degradation in Caenorhabditis elegans

2002 • 375 citations

DNA binding is required for the apoptogenic action of apoptosis inducing factor

2002 • 342 citations

The transport of proteins into the nucleus requires the 70-kilodalton heat shock protein or its cytosolic cognate.

1992 • 335 citations

Dominant cell death induction by extramitochondrially targeted apoptosis‐inducing factor

2001 • 244 citations

Apoptosis Control in Syncytia Induced by the HIV Type 1–Envelope Glycoprotein Complex

2000 • 213 citations

Over‐expression of hsp70 confers tumorigenicity to mouse fibrosarcoma cells

1995 • 178 citations

Human Immunodeficiency Virus 1 Envelope Glycoprotein Complex-Induced Apoptosis Involves Mammalian Target of Rapamycin/Fkbp12-Rapamycin–Associated Protein–Mediated P53 Phosphorylation

2001 • 147 citations

Positive and negative regulation of apoptotic pathways by cytotoxic agents in hematological malignancies

2000 • 137 citations

Oncogenic potential of Hsp72

1999 • 117 citations

T Cell Lymphoma in Transgenic Mice Expressing the HumanHsp70Gene

1996 • 106 citations

Selective depletion of inducible HSP70 enhances immunogenicity of rat colon cancer cells

2001 • 84 citations

Optimization of capillary chromatography ion trap-mass spectrometry for identification of gel-separated proteins

1998 • 36 citations