Induction of Fas Ligand-Mediated Apoptosis by Interferon-α

The Fas Death Factor

1995 • 4,070 citations

The Nature of the Principal Type 1 Interferon-Producing Cells in Human Blood

1999 • 2,255 citations

NATURAL KILLER CELLS IN ANTIVIRAL DEFENSE: Function and Regulation by Innate Cytokines

1999 • 2,128 citations

Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon

1999 • 1,754 citations

Monoclonal Antibody-Mediated Tumor Regression by Induction of Apoptosis

1989 • 1,739 citations

Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes.

1994 • 1,722 citations

Immune Interferon in the Circulation of Patients with Autoimmune Disease

1979 • 907 citations

Anti-viral activity induced by culturing lymphocytes with tumor-derived or virus-transformed cells. Enhancement of human natural killer cell activity by interferon and antagonistic inhibition of susceptibility of target cells to lysis.

1978 • 744 citations

Cytokine therapeutics: lessons from interferonalpha.

1994 • 703 citations

Type I IFNs Enhance the Terminal Differentiation of Dendritic Cells

1998 • 610 citations

Epstein-Barr virus latent membrane protein (LMP1) and nuclear proteins 2 and 3C are effectors of phenotypic changes in B lymphocytes: EBNA-2 and LMP1 cooperatively induce CD23

1990 • 585 citations

Interferon regulatory factors: the next generation

1999 • 550 citations

Augmentation by interferon of human natural and antibody-dependent cell-mediated cytotoxicity

1979 • 532 citations

Natural Killer (NK) Cell–mediated Cytotoxicity: Differential Use of TRAIL and Fas Ligand by Immature and Mature Primary Human NK Cells

1998 • 517 citations

Biological properties of recombinant alpha-interferons: 40th anniversary of the discovery of interferons.

1998 • 486 citations

Monocyte-mediated Tumoricidal Activity via the Tumor Necrosis Factor–related Cytokine, TRAIL

1999 • 470 citations

Systemic Lupus Erythematosus: Presence in Human Serum of an Unusual Acid-Labile Leukocyte Interferon

1982 • 460 citations

Human Fas ligand: gene structure, chromosomal location and species specificity

1994 • 435 citations

IFN-gamma-inducing factor up-regulates Fas ligand-mediated cytotoxic activity of murine natural killer cell clones.

1996 • 425 citations

Characterization of early IL-12, IFN-alphabeta, and TNF effects on antiviral state and NK cell responses during murine cytomegalovirus infection.

1996 • 413 citations

Degranulation plays an essential part in regulating cell surface expression of Fas ligand in T cells and natural killer cells

1999 • 385 citations

Fas-mediated cytotoxicity by freshly isolated natural killer cells.

1995 • 372 citations

An IRF-1-dependent pathway of DNA damage-induced apoptosis in mitogen-activated T lymphocytes

1997 • 364 citations

Possible induction of systemic lupus erythematosus by interferon‐α treatment in a patient with a malignant carcinoid tumour

1990 • 358 citations

The Interferon-induced Double-Stranded RNA-Activated Protein Kinase Induces Apoptosis

1994 • 322 citations

The neglected role of type I interferon in the T-cell response: implications for its clinical use

1996 • 306 citations

IFN-gamma induces cell growth inhibition by Fas-mediated apoptosis: requirement of STAT1 protein for up-regulation of Fas and FasL expression.

1998 • 283 citations

A Study of the Interferon Antiviral Mechanism: Apoptosis Activation by the 2–5A System

1997 • 262 citations

Differential Induction of Apoptosis by Fas–Fas Ligand Interactions in Human Monocytes and Macrophages

1997 • 243 citations

Interferon inhibits DNA Synthesis induced in Mouse Lymphocyte Suspensions by Phytohaemagglutinin or by Allogeneic Cells

1972 • 226 citations

Spontaneous production of interleukin-10 by B lymphocytes and monocytes in systemic lupus erythematosus.

1993 • 201 citations

Positive self regulation of cytotoxicity in human natural killer cells by production of interferon upon exposure to influenza and herpes viruses.

1982 • 188 citations

Perforin, Fas ligand, and tumor necrosis factor are the major cytotoxic molecules used by lymphokine-activated killer cells.

1996 • 187 citations

Interleukin-10 promotes activation-induced cell death of SLE lymphocytes mediated by Fas ligand.

1997 • 178 citations

Transforming Growth Factor β1 Inhibits Fas Ligand Expression and Subsequent Activation-induced Cell Death in T Cells via Downregulation of c-Myc

1999 • 177 citations

High expression of APO-1 (CD95) on T lymphocytes from human immunodeficiency virus-1-infected children [letter]

1994 • 174 citations

Regulation of CD95 (Fas) ligand expression by TCR-mediated signaling events.

1997 • 167 citations

Involvement of Fas-Mediated Apoptosis in the Inhibitory Effects of Interferon-α in Chronic Myelogenous Leukemia

1997 • 152 citations

Fc receptor-induced expression of Fas ligand on activated NK cells facilitates cell-mediated cytotoxicity and subsequent autocrine NK cell apoptosis.

1996 • 129 citations

Development of systemic lupus erythematosus after interferon therapy for chronic myelogenous leukemia

1991 • 128 citations

Lymphocyte-Mediated Cytolysis and Disease

1996 • 126 citations

Regression of basal cell carcinoma by intralesional interferon-alpha treatment is mediated by CD95 (Apo-1/Fas)-CD95 ligand-induced suicide.

1997 • 124 citations

The spontaneous apoptotic cell death of normal human lymphocytes in vitro: The release of, and immunoproliferative response to, nucleosomes in vitro

1991 • 108 citations

Antibodies against double-stranded DNA and development of polymyositis during treatment with interferon

1998 • 105 citations

Correlation Between Endogenous Interferon and the Clinical Evolution of Patients with Argentine Hemorrhagic Fever

1985 • 105 citations

Expression of the APO-1 antigen in Burkitt lymphoma cell lines correlates with a shift towards a lymphoblastoid phenotype

1992 • 97 citations

Nonsecretory apoptotic killing by human NK cells.

1996 • 94 citations

Role of Spontaneous and Interleukin-2–Induced Natural Killer Cell Activity in the Cytotoxicity and Rejection of Fas+and Fas− Tumor Cells

1998 • 88 citations

REGULATION OF FAS AND FAS-LIGAND EXPRESSION IN NK CELLS BY CYTOKINES AND THE INVOLVEMENT OF FAS-LIGAND IN NK/LAK CELL-MEDIATED CYTOTOXICITY

1997 • 86 citations

Interleukin-15 Induces the Expression of mRNAs of Cytolytic Mediators and Augments Cytotoxic Activities in Primary Murine Lymphocytes

1996 • 68 citations

Interferon production during lymphocytic choriomeningitis virus infection of nude and normal mice

1977 • 66 citations

Tubuloreticular inclusions in peripheral blood mononuclear cells related to systemic therapy with alpha-interferon.

1985 • 63 citations

The participation of the Fas-mediated cytotoxic pathway by natural killer cells is tumor-cell-dependent

1997 • 62 citations

Differential increase of Fas ligand expression on metastatic and thin or thick primary melanoma cells compared with interleukin-10

1999 • 38 citations

Serum alpha-interferon in lower respiratory tract infections of children

1996 • 21 citations

Human α-lymphoblastoid interferon

1985 • 4 citations