Expression inEscherichiaof chemically synthesized gene for the human immune Interferon

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

A new method for sequencing DNA.

1977 • 7,941 citations

Determinant of cistron specificity in bacterial ribosomes

1975 • 1,363 citations

Codon catalog usage is a genome strategy modulated for gene expressivity

1981 • 951 citations

Expression in Escherichia coli of a Chemically Synthesized Gene for the Hormone Somatostatin

1977 • 829 citations

Codon catalog usage and the genome hypothesis

1980 • 772 citations

Expression of human immune interferon cDNA in E. coli and monkey cells

1982 • 703 citations

Human leukocyte interferon produced by E. coli is biologically active

1980 • 528 citations

DNA sequence analysis: a general, simple and rapid method for sequencing large oligodeoxyribonucleotide fragments by mapping

1974 • 395 citations

Codon frequencies in 119 individual genes confirm corsistent choices of degenerate bases according to genome type

1980 • 370 citations

Expression of a human gene for interferon in yeast

1981 • 332 citations

A restriction map of the bacteriophage T4 genome

1980 • 326 citations

Differential efficacies of human type I and type II interferons as antiviral and antiproliferative agents.

1980 • 286 citations

Synthesis of human fibroblast interferon by E. coli

1980 • 240 citations

Arylsulfonyltetrazoles, new coupling reagents and further improvements in the triester method for the synthesis of deoxyribooligonucleotides¹

1977 • 235 citations

Maximizing gene expression on a plasmid using recombination in vitro

1978 • 200 citations

Molecular cloning of human immune interferon cDNA and its expression in eukaryotic cells

1982 • 192 citations

Rapid synthesis of oligodeoxyribonucleotides VI. Effident, mechanised synthesis of heptadecadeoxyribonucleotides by an improved solid phase phosphotriester route

1981 • 185 citations

Total synthesis of a human leukocyte interferon gene

1981 • 160 citations

Expression of the human fibroblast interferon gene in Escherichia coli.

1980 • 130 citations

Rapid synthesis of oligodeoxyribonucleotides IV. Improved solid phase synthesis of oligodeoxy-ribonucleotides through phosphotriester intermediates

1980 • 129 citations

DNA chain length markers and the influence of base composition on electrophoretic mobility of oligodeoxyribonucleotides in plyacrylamide-gels

1979 • 106 citations

Immune (γ) interferon produced by a human T-lymphoblast cell line

1981 • 99 citations

The nudeotide sequence of the promoter and the ammo-terminal region of alkaline phosphatase structural gene (phoA) of Escherichia coli

1981 • 94 citations

Solid-phase synthesis of polynucleotides. III. Synthesis of polynucleotides with defined sequences by the block coupling phosphotriester method

1980 • 92 citations

Purification of two subspecies of human gamma (immune) interferon.

1982 • 90 citations

Solid-phase synthesis of polynucleotides. IV. Usage of polystyrene resins for the synthesis of polydeoxyribonucleotides by the phosphotriester method

1980 • 77 citations

Solid-phase synthesis of polynucleotides. II. Synthesis of polythymidylic acids by the block coupling phosphotriester method

1980 • 76 citations

Simplifications in the synthesis of short oligonucleotide blocks

1980 • 71 citations

Bacterial synthesis of a novel human leukocyte interferon

1981 • 61 citations

Monoclonal antibody against human IFN-γ

1982 • 47 citations

Rapid synthesis of oligodeoxyribonucleotides II¹. Machine-aided solid-phase syntheses of two nonanucleotides and an octanucleotide

1977 • 35 citations

Proteins synthesized in minicells containing plasmid ColE1 and its mutants

1978 • 33 citations

Expression in Escherichia coli of chemically synthesized gene for a novel opiate peptide α-neo-endorphin

1982 • 20 citations

Rapid synthesis of oligodeoxyribonucleotides III. Effect of added carboxylate ion on the efficiency of internucleotide bond formation. Solid-phase synthesis of the dodecanucleotide, d(pT-A-A-C-T-G-C-T-C-A-C-T)

1979 • 12 citations