Mannose Polyethylenimine Conjugates for Targeted DNA Delivery into Dendritic Cells

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.

1994 • 5,204 citations

Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor.

1992 • 3,751 citations

T cell receptor antagonist peptides induce positive selection

1994 • 2,818 citations

Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products.

1995 • 2,531 citations

Proliferating dendritic cell progenitors in human blood.

1994 • 1,922 citations

Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells

1997 • 1,143 citations

The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing

1995 • 959 citations

Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo.

1996 • 922 citations

Receptor-mediated in vitro gene transformation by a soluble DNA carrier system.

1987 • 841 citations

The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems.

1994 • 668 citations

Transferrin-polycation conjugates as carriers for DNA uptake into cells.

1990 • 657 citations

Constitutive class I-restricted exogenous presentation of self antigens in vivo.

1996 • 637 citations

A Powerful Nonviral Vector for In Vivo Gene Transfer into the Adult Mammalian Brain: Polyethylenimine

1996 • 544 citations

Current protocols in human genetics

1995 • 498 citations

Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes.

1992 • 483 citations

Dendritic Cells as Adjuvants for Immune-mediated Resistance to Tumors

1997 • 432 citations

Adenovirus enhancement of transferrin-polylysine-mediated gene delivery.

1991 • 431 citations

Dendritic Cells Genetically Modified with an Adenovirus Vector Encoding the cDNA for a Model Antigen Induce Protective and Therapeutic Antitumor Immunity

1997 • 390 citations

Coupling of cell-binding ligands to polyethylenimine for targeted gene delivery

1997 • 363 citations

Colorimetric determination of neutral sugars by a resorcinol sulfuric acid micromethod

1988 • 343 citations

Transferrin-polycation-mediated introduction of DNA into human leukemic cells: stimulation by agents that affect the survival of transfected DNA or modulate transferrin receptor levels.

1990 • 340 citations

Gene transfer into hepatocytes using asialoglycoprotein receptor mediated endocytosis of DNA complexed with an artificial tetra-antennary galactose ligand

1992 • 325 citations

Dendritic cells: from ontogenetic orphans to myelomonocytic descendants

1996 • 324 citations

A comparison of gene transfer methods in human dendritic cells.

1997 • 315 citations

The endocytic activity of dendritic cells.

1995 • 308 citations

Receptor-mediated endocytosis of transferrin-polycation conjugates: an efficient way to introduce DNA into hematopoietic cells.

1990 • 275 citations

Complexes of Adenovirus with Polycationic Polymers and Cationic Lipids Increase the Efficiency of Gene Transfer in Vitro and in Vivo

1997 • 268 citations

Redundant control of adenovirus late gene expression by early region 4

1989 • 261 citations

Effects of exogenous amines on mammalian cells, with particular reference to membrane flow

1984 • 252 citations

The mannose receptor and other macrophage lectins

1992 • 248 citations

Polyethylenimine (PEI) is a simple, inexpensive and effective reagent for condensing and linking plasmid DNA to adenovirus for gene delivery

1997 • 196 citations

Genetic immunization for the melanoma antigen MART-1/Melan-A using recombinant adenovirus-transduced murine dendritic cells.

1997 • 182 citations

Receptor-mediated gene transfer into macrophages.

1996 • 176 citations

Lipopolysaccharide is a frequent contaminant of plasmid DNA preparations and can be toxic to primary human cells in the presence of adenovirus.

1994 • 167 citations

An Evaluation of Receptor‐Mediated Gene Transfer Using Synthetic DNA‐Ligand Complexes

1994 • 144 citations

Gene Transfer by DNA/Glycosylated Polylysine Complexes into Human Blood Monocyte-Derived Macrophages

1996 • 142 citations

Dendritic cells hold promise for immunotherapy

1997 • 135 citations

Non-viral approaches to gene therapy

1993 • 133 citations

Leukemic Transformation with Avian Myeloblastosis Virus: Present Status

1975 • 130 citations

Expression of a mannose/fucose membrane lectin on human dendritic cells

1996 • 120 citations

[42] Receptor-mediated transport of DNA into eukaryotic cells

1993 • 115 citations

Dendritic cells

1998 • 107 citations

Efficient Gene Delivery into Human Dendritic Cells by Adenovirus Polyethylenimine and Mannose Polyethylenimine Transfection

1999 • 98 citations

Chicken adenovirus (CELO virus) particles augment receptor-mediated DNA delivery to mammalian cells and yield exceptional levels of stable transformants

1993 • 93 citations

v-erbA overexpression is required to extinguish c-erbA function in erythroid cell differentiation and regulation of the erbA target gene CAII.

1991 • 83 citations

Psoralen Treatment of Adenovirus Particles Eliminates Virus Replication and Transcription While Maintaining the Endosomolytic Activity of the Virus Capsid

1994 • 82 citations

Successful retroviral mediated transduction of a reporter gene in human dendritic cells: feasibility of therapy with gene-modified antigen presenting cells.

1997 • 77 citations

Gene-based strategies for the immunotherapy of cancer

1997 • 77 citations

Retroviral interleukin-7 gene transfer into human dendritic cells enhances T cell activation

1998 • 54 citations

Delivery of bacterial artificial chromosomes into mammalian cells with psoralen-inactivated adenovirus carrier

1997 • 49 citations

Human adenovirus type 2 protein IIIa I. Purification and characterization

1980 • 40 citations

Gene-Modified Dendritic Cells by Receptor-Mediated Transfection

1998 • 14 citations

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