Gene-Modified Dendritic Cells by Receptor-Mediated Transfection

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.

1994 • 5,204 citations

Proliferating dendritic cell progenitors in human blood.

1994 • 1,922 citations

Generation of mature dendritic cells from human blood An improved method with special regard to clinical applicability

1996 • 1,138 citations

Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity

1995 • 1,097 citations

Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo.

1996 • 922 citations

Therapy of murine tumors with tumor peptide-pulsed dendritic cells: dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines.

1996 • 849 citations

DNA–based immunization by in vivo transfection of dendritic cells

1996 • 849 citations

Chicken hematopoietic cells transformed by seven strains of defective avian leukemia viruses display three distinct phenotypes of differentiation

1979 • 769 citations

An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3.

1994 • 743 citations

Improved methods for the generation of dendritic cells from nonproliferating progenitors in human blood

1996 • 696 citations

Transferrin-polycation conjugates as carriers for DNA uptake into cells.

1990 • 657 citations

Murine dendritic cells loaded in vitro with soluble protein prime cytotoxic T lymphocytes against tumor antigen in vivo.

1996 • 561 citations

Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes.

1992 • 483 citations

Adenovirus enhancement of transferrin-polylysine-mediated gene delivery.

1991 • 431 citations

Transferrin-polycation-mediated introduction of DNA into human leukemic cells: stimulation by agents that affect the survival of transfected DNA or modulate transferrin receptor levels.

1990 • 340 citations

Dendritic cells: from ontogenetic orphans to myelomonocytic descendants

1996 • 324 citations

A comparison of gene transfer methods in human dendritic cells.

1997 • 315 citations

Murine dendritic cells pulsed in vitro with tumor antigen induce tumor resistance in vivo

1994 • 300 citations

Receptor-mediated endocytosis of transferrin-polycation conjugates: an efficient way to introduce DNA into hematopoietic cells.

1990 • 275 citations

Dendritic cells as initiators of tumor immune responses: a possible strategy for tumor immunotherapy?

1995 • 264 citations

Embryonic erythroid differentiation in the human leukemic cell line K562.

1981 • 183 citations

Generation of immunostimulatory dendritic cells from human CD34+ hematopoietic progenitor cells of the bone marrow and peripheral blood.

1995 • 175 citations

Expression of a mannose/fucose membrane lectin on human dendritic cells

1996 • 120 citations

[42] Receptor-mediated transport of DNA into eukaryotic cells

1993 • 115 citations

Dendritic cells generated from peripheral blood transfected with human tyrosinase induce specific T cell activation

1995 • 106 citations

Gene-based strategies for the immunotherapy of cancer

1997 • 77 citations