Reduced Light-dependent Phosphorylation of an Analog Visual Pigment Containing 9-Demethylretinal as Its Chromophore

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Phosphodiesterase activation by photoexcited rhodopsin is quenched when rhodopsin is phosphorylated and binds the intrinsic 48-kDa protein of rod outer segments.

1986 • 781 citations

Amplification and kinetics of the activation steps in phototransduction

1993 • 645 citations

Visual excitation and recovery

1991 • 530 citations

THE MOLAR EXTINCTION OF RHODOPSIN

1953 • 444 citations

Light-dependent phosphorylation of rhodopsin: number of phosphorylation sites

1982 • 441 citations

THE MOLECULAR MECHANISM OF VISUAL EXCITATION AND ITS RELATION TO THE STRUCTURE AND COMPOSITION OF THE ROD OUTER SEGMENT

1987 • 264 citations

Lipid requirements for rhodopsin regenerability

1973 • 250 citations

Light-dependent delay in the falling phase of the retinal rod photoresponse

1992 • 232 citations

Kinetics, binding constant, and activation energy of the 48-kDa protein-rhodopsin complex by extra-metarhodopsin II

1989 • 193 citations

Inactivation of photoexcited rhodopsin in retinal rods: the roles of rhodopsin kinase and 48-kDa protein (arrestin)

1988 • 185 citations

Rod Outer Segment Retinol Dehydrogenase: Substrate Specificity and Role in Phototransduction

1994 • 171 citations

Purification and characterization of rhodopsin kinase.

1988 • 149 citations

S-Potentials in the Skate Retina

1971 • 149 citations

Mass spectrometric identification of phosphorylation sites in bleached bovine rhodopsin

1993 • 140 citations

Removal of the 9-methyl group of retinal inhibits signal transduction in the visual process. A fourier transform infrared and biochemical investigation

1989 • 131 citations

Regulation of transducin GTPase activity in bovine rod outer segments.

1994 • 131 citations

Amplification of phosphodiesterase activation is greatly reduced by rhodopsin phosphorylation

1986 • 130 citations

Rhodopsin kinase: substrate specificity and factors that influence activity

1988 • 125 citations

Interaction between photoactivated rhodopsin and its kinase: Stability and kinetics of complex formation

1993 • 122 citations

Regulation of rhodopsin kinase by autophosphorylation.

1991 • 120 citations

The spectral properties of some visual pigment analogs

1973 • 115 citations

Light activation of one rhodopsin molecule causes the phosphorylation of hundreds of others. A reaction observed in electropermeabilized frog rod outer segments exposed to dim illumination.

1990 • 110 citations

Reciprocal effects of an inhibitory factor on catalytic activity and noncatalytic cGMP binding sites of rod phosphodiesterase.

1982 • 105 citations

Visual arrestin binding to rhodopsin. Intramolecular interaction between the basic N terminus and acidic C terminus of arrestin may regulate binding selectivity.

1994 • 85 citations

Effect of bleached rhodopsin on signal amplification in rod visual receptors

1990 • 80 citations

Series of synthetic visual pigments from cattle opsin and homologs of retinal

1969 • 69 citations

Relief of opsin desensitization and prolonged excitation of rod photoreceptors by 9-desmethylretinal.

1994 • 67 citations

Evidence for the prolonged photoactivated lifetime of an analogue visual pigment containing 11-cis9-desmethylretinal

1994 • 64 citations

Photic modulation of a highly sensitive, near-infrared light-scattering signal recorded from intact retinal photoreceptors.

1988 • 62 citations

Depalmitylation with hydroxylamine alters the functional properties of rhodopsin.

1991 • 61 citations

Opsins with mutations at the site of chromophore attachment constitutively activate transducin but are not phosphorylated by rhodopsin kinase.

1994 • 48 citations

Activation of rhodopsin phosphorylation is triggered by the lumirhodopsin–metarhodopsin I transition

1983 • 41 citations

Schiff-base deprotonation is mandatory for light-dependent rhodopsin phosphorylation

1989 • 18 citations

Polyethylene glycol as a hydration agent in oriented membrane bilayer samples

1993 • 13 citations