Recruitment of IRAK to the interleukin 1 receptor complex requires interleukin 1 receptor accessory protein

A novel genetic system to detect protein–protein interactions

1989 • 6,022 citations

Function and Activation of NF-kappaB in the Immune System

1994 • 4,698 citations

Biologic basis for interleukin-1 in disease

1996 • 4,324 citations

TRAF6 is a signal transducer for interleukin-1

1996 • 1,287 citations

TNF activates NF-κB by phosphatidylcholine-specific phospholipase C-induced “Acidic” sphingomyelin breakdown

1992 • 1,058 citations

Two TNF receptors

1992 • 1,048 citations

TRAF2-Mediated Activation of NF-κB by TNF Receptor 2 and CD40

1995 • 1,046 citations

cDNA Expression Cloning of the IL-1 Receptor, a Member of the Immunoglobulin Superfamily

1988 • 896 citations

IRAK: A Kinase Associated with the Interleukin-1 Receptor

1996 • 894 citations

Molecular Cloning and Characterization of a Second Subunit of the Interleukin 1 Receptor Complex

1995 • 634 citations

SIGNALING PATHWAYS THAT ESTABLISH THE DORSAL-VENTRAL PATTERN OF THE DROSOPHILA EMBRYO

1995 • 348 citations

TRAF5, an Activator of NF-κB and Putative Signal Transducer for the Lymphotoxin-β Receptor

1996 • 343 citations

Three NF-kappa B binding sites in the human E-selectin gene required for maximal tumor necrosis factor alpha-induced expression.

1994 • 334 citations

The Interleukin-1 Receptor Accessory Protein (IL-1RAcP) Is Essential for IL-1-induced Activation of Interleukin-1 Receptor-associated Kinase (IRAK) and Stress-activated Protein Kinases (SAP Kinases)

1997 • 311 citations

Anatomy of TRAF2

1996 • 302 citations

Amino acids conserved in interleukin-1 receptors (IL-1Rs) and the Drosophila toll protein are essential for IL-1R signal transduction.

1992 • 180 citations

NF-κB Activation by Interleukin-1 (IL-1) Requires an IL-1 Receptor-associated Protein Kinase Activity

1995 • 172 citations

Activation of the kinase Pelle by Tube in the dorsoventral signal transduction pathway of Drosophila embryo

1994 • 120 citations

T-cell interleukin 1 receptor cDNA expressed in Chinese hamster ovary cells regulates functional responses to interleukin 1.

1989 • 97 citations

Interaction of the pelle kinase with the membrane-associated protein tube is required for transduction of the dorsoventral signal in Drosophila embryos

1995 • 71 citations

Fluorescence Resonance Energy Transfer Reveals Interleukin (IL)-1-dependent Aggregation of IL-1 Type I Receptors That Correlates with Receptor Activation

1995 • 55 citations

Structure and function of the intracellular portion of the mouse interleukin 1 receptor (type I). Determining the essential region for transducing signals to activate the interleukin 8 gene

1993 • 49 citations

The cytoplasmic domain of the interleukin-1 receptor is required for nuclear factor-kappa B signal transduction.

1994 • 45 citations