The Interleukin-1 Receptor Accessory Protein (IL-1RAcP) Is Essential for IL-1-induced Activation of Interleukin-1 Receptor-associated Kinase (IRAK) and Stress-activated Protein Kinases (SAP Kinases)

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Biologic basis for interleukin-1 in disease

1996 • 4,324 citations

pEF-BOS, a powerful mammalian expression vector

1990 • 1,641 citations

TRAF6 is a signal transducer for interleukin-1

1996 • 1,287 citations

Ultraviolet Light and Osmotic Stress: Activation of the JNK Cascade Through Multiple Growth Factor and Cytokine Receptors

1996 • 1,046 citations

Interleukin-1 Type II Receptor: A Decoy Target for IL-1 That Is Regulated by IL-4

1993 • 972 citations

cDNA Expression Cloning of the IL-1 Receptor, a Member of the Immunoglobulin Superfamily

1988 • 896 citations

IRAK: A Kinase Associated with the Interleukin-1 Receptor

1996 • 894 citations

A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types.

1991 • 677 citations

Molecular Cloning and Characterization of a Second Subunit of the Interleukin 1 Receptor Complex

1995 • 634 citations

Interleukin 1 signaling occurs exclusively via the type I receptor.

1993 • 609 citations

A critical role for interleukin‐1 receptor accessory protein in interleukin‐1 signaling

1997 • 174 citations

NF-κB Activation by Interleukin-1 (IL-1) Requires an IL-1 Receptor-associated Protein Kinase Activity

1995 • 172 citations

Interleukin 1-dependent induction of both interleukin 2 secretion and interleukin 2 receptor expression by thymoma cells.

1986 • 133 citations

Interleukin‐1‐induced activation of a protein kinase co‐precipitating with the type I interleukin‐1 receptor in T cells

1994 • 76 citations

Co‐expression of mRNA for type I and type II Interleukin‐1 receptors and the IL‐1 receptor accessory protein correlates to IL‐1 responsiveness

1996 • 53 citations

Interleukin 1 alpha activates two forms of p54 alpha mitogen-activated protein kinase in rabbit liver.

1994 • 51 citations

Interleukin 1 activates jun N‐terminal kinases JNK1 and JNK2 but not extracellular regulated MAP kinase (ERK) in human glomerular mesangial cells

1996 • 36 citations

Internalization of interleukin 1 (IL 1) correlates with IL 1‐induced IL 2 receptor expression and IL 2 secretion of EL4 thymoma cells

1989 • 34 citations

An NF‐χB‐like element plays an essential role in interleukin‐1‐mediated costimulation of the mouse interleukin‐2 promoter

1993 • 21 citations

A chimeric type II/type I interleukin-1 receptor can mediate interleukin-1 induction of gene expression in T cells

1993 • 20 citations

Comparison of IL-1α effectiveness in activating murine pre-B and T cell lines

1993 • 10 citations