T-cell interleukin 1 receptor cDNA expressed in Chinese hamster ovary cells regulates functional responses to interleukin 1.

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

1982 • 2,753 citations

Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs

1985 • 1,594 citations

cDNA Expression Cloning of the IL-1 Receptor, a Member of the Immunoglobulin Superfamily

1988 • 896 citations

Human insulin receptors mutated at the ATP-binding site lack protein tyrosine kinase activity and fail to mediate postreceptor effects of insulin.

1987 • 648 citations

Isolation and partial characterization of the Drosophila alcohol dehydrogenase gene.

1980 • 570 citations

Membrane Receptors and Hormone Action

1976 • 484 citations

Interleukin 1 stimulates fibroblasts to produce granulocyte-macrophage colony-stimulating activity and prostaglandin E2.

1986 • 458 citations

The cell surface receptors for interleukin-1α and interleukin-1β are identical

1986 • 422 citations

Regulation of fibroblast cyclooxygenase synthesis by interleukin-1.

1988 • 401 citations

Replacement of lysine residue 1030 in the putative ATP-binding region of the insulin receptor abolishes insulin- and antibody-stimulated glucose uptake and receptor kinase activity.

1987 • 399 citations

Synergy of interleukin 1 and granulocyte colony-stimulating factor: in vivo stimulation of stem-cell recovery and hematopoietic regeneration following 5-fluorouracil treatment of mice.

1987 • 380 citations

Interleukin 1 regulates hematopoietic activity, a role previously ascribed to hemopoietin 1.

1987 • 309 citations

Cloning, sequence and expression of human interleukin-2 receptor

1984 • 272 citations

Interleukin 1 stimulates fibroblasts to synthesize granulocyte-macrophage and granulocyte colony-stimulating factors. Mechanism for the hematopoietic response to inflammation.

1988 • 247 citations

Additive effects of interleukin 1 and tumour necrosis factor-alpha on the accumulation of the three granulocyte and macrophage colony-stimulating factor mRNAs in human endothelial cells.

1987 • 238 citations

Identification of a common class of high affinity receptors for both types of porcine interleukin-1 on connective tissue cells

1986 • 219 citations

Enhancing the efficiency of DNA-mediated gene transfer in mammalian cells

1981 • 208 citations

Isolation and characterization of the cDNA for murine granulocyte colony-stimulating factor.

1986 • 188 citations

Similarity between the interleukin 1 receptors on a murine T-lymphoma cell line and on a murine fibroblast cell line.

1986 • 144 citations

Interleukin‐1 regulation of hematopoietic growth factor production by human stromal fibroblasts

1988 • 136 citations

Interleukin 1: more than a mediator between leukocytes

1988 • 120 citations

Affinity purification and chemical analysis of the interleukin-1 receptor.

1988 • 86 citations

Association of a protein with membrane vesicles at the collisional limit: studies with blood coagulation factor Va light chain also suggest major differences between small and large unilamellar vesicles

1987 • 44 citations

Linking functional domains of the human insulin receptor with the bacterial aspartate receptor.

1986 • 25 citations

Development and characterization of antiserum to murine granulocyte-macrophage colony-stimulating factor.

1986 • 23 citations