Sodium restriction prevents cardiac hypertrophy and oxidative stress in angiotensin II hypertension

Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells.

1994 • 2,753 citations

Hyperfiltration in remnant nephrons: a potentially adverse response to renal ablation

1981 • 1,664 citations

Molecular characterization of angiotensin II--induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts. Critical role of the AT1 receptor subtype.

1993 • 1,420 citations

Role of Superoxide in Angiotensin II–Induced but Not Catecholamine-Induced Hypertension

1997 • 831 citations

Inhibitory Effects of Antioxidants on Neonatal Rat Cardiac Myocyte Hypertrophy Induced by Tumor Necrosis Factor-α and Angiotensin II

1998 • 509 citations

Peroxynitrite Is a Major Contributor to Cytokine-Induced Myocardial Contractile Failure

2000 • 448 citations

Angiotensin II causes vascular hypertrophy in part by a non-pressor mechanism.

1991 • 397 citations

Angiotensin II stimulation of protein synthesis and cell growth in chick heart cells

1990 • 358 citations

Role of NADPH Oxidase in the Vascular Hypertrophic and Oxidative Stress Response to Angiotensin II in Mice

2001 • 336 citations

Angiotensin II induces fibronectin expression associated with cardiac fibrosis in the rat.

1994 • 225 citations

BP as a Determinant of Cardiac Left Ventricular Muscle Mass

1983 • 215 citations

Angiotensin II Stimulation of Left Ventricular Hypertrophy in Adult Rat Heart

1992 • 207 citations

Reactive oxygen species may contribute to reduced endothelium-dependent dilation in rats fed high salt

2000 • 183 citations

Angiotensin II-mediated expression of p27Kip1 and induction of cellular hypertrophy in renal tubular cells depend on the generation of oxygen radicals

1998 • 172 citations

Cerivastatin prevents angiotensin II-induced renal injury independent of blood pressure- and cholesterol-lowering effects

2000 • 170 citations

Simvastatin Prevents Angiotensin II–Induced Cardiac Alteration and Oxidative Stress

2002 • 154 citations

Role of Nitric Oxide and Its Interaction With Superoxide in the Suppression of Cardiac Muscle Mitochondrial Respiration

1996 • 153 citations

Sodium Induces Hypertrophy of Cultured Myocardial Myoblasts and Vascular Smooth Muscle Cells

1998 • 153 citations

Systemic and Regional Hemodynamic Responses to Tempol in Angiotensin II–Infused Hypertensive Rats

2001 • 144 citations

Antioxidants Block Angiotensin II-Induced Increases in Blood Pressure and Endothelin

2001 • 138 citations

Angiotensin type 2 receptors mediate depressor phase of biphasic pressure response to angiotensin

1993 • 133 citations

Free radical production and angiotensin

2000 • 132 citations

Regulation of vascular angiotensin II receptors in the rat during altered sodium intake.

1981 • 128 citations

Prevention of the Cardiovascular and Renal Effects of Angiotensin II by Endothelin Blockade

1998 • 127 citations

Paracrine Role of Adventitial Superoxide Anion in Mediating Spontaneous Tone of the Isolated Rat Aorta in Angiotensin II-Induced Hypertension

1999 • 120 citations

Relationship between dietary sodium intake, hemodynamics, and cardiac mass in SHR and WKY rats

1993 • 107 citations

Glomerular hypertrophy accelerates hypertensive glomerular injury in rats

1991 • 105 citations

Sodium and left ventricular mass in untreated hypertensive and normotensive subjects

1992 • 104 citations

Effect of a high-salt diet on oxidant enzyme activity in skeletal muscle microcirculation

2002 • 91 citations

Superiority of salt restriction over diuretics in reducing renal hypertrophy and injury in uninephrectomized SHR

1990 • 77 citations

Role of oxygen-derived free radicals in acute angiotensin II--induced hypertensive vascular disease in the rat.

1990 • 76 citations

Dietary sodium intake and left ventricular hypertrophy in normotensive rats

1991 • 73 citations

Salt restriction inhibits renal growth and stabilizes injury in rats with established renal disease.

1996 • 62 citations

Role of sodium in hypertensive cardiac hypertrophy.

1985 • 59 citations

Angiotensin II Increases Left Ventricular Mass Without Affecting Myosin Isoform mRNAs

1996 • 57 citations

Interaction between sodium intake, angiotensin II, and blood pressure as a cause of cardiac hypertrophy

2001 • 57 citations

Angiotensin II activates Na+-H+ exchange and stimulates growth in cultured vascular smooth muscle cells

1988 • 53 citations

Altered pressure natriuresis in chronic angiotensin II hypertension in rats

1994 • 49 citations

Role of sodium in modulation of myocardial hypertrophy in renal hypertensive rats.

1986 • 44 citations

Influence of sodium intake on in vivo left ventricular anatomy in experimental renovascular hypertension

1993 • 41 citations

Microalbuminuria, left ventricular mass and ambulatory blood pressure in essential hypertension.

1996 • 31 citations

Antioxidant status of the hypertrophic heart of Dahl hypertensive rat as a model for evaluation of antioxidants

2001 • 28 citations

Sodium, angiotensin II, blood pressure, and cardiac hypertrophy

1998 • 25 citations

The Role of the Na+/H+ Antiporter in Human Neutrophil NADPH-Oxidase Activation

1988 • 18 citations

Chemotherapy for Lymphoma in a Patient With Common Variable Immunodeficiency

1982 • 13 citations

Sodium but not chloride ion modulates left ventricular hypertrophy in two-kidney, one clip hypertension

1994 • 11 citations

Dietary sodium restriction and the development of two-kidney, one-clip hypertension in young versus adult rats

1992 • 5 citations