Isolation of vascular smooth muscle cell cultures with altered responsiveness to the antiproliferative effect of heparin

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

1983 • 2,871 citations

Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

1983 • 1,857 citations

Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

1983 • 1,358 citations

A quick and simple method for the quantitation of lactate dehydrogenase release in measurements of cellular cytotoxicity and tumor necrosis factor (TNF) activity

1988 • 1,288 citations

Monoclonal antibodies specific for simian virus 40 tumor antigens

1981 • 1,110 citations

Construction and applications of a highly transmissible murine retrovirus shuttle vector

1984 • 1,020 citations

Cultured endothelial cells produce heparinlike inhibitor of smooth muscle cell growth

1981 • 685 citations

STRUCTURE AND FUNCTION OF SIMIAN VIRUS 40 LARGE TUMOR ANTIGEN

1992 • 506 citations

Establishment and characterization of multipotent neural cell lines using retrovirus vector‐mediated oncogene transfer

1990 • 375 citations

The roles of individual polyoma virus early proteins in oncogenic transformation

1982 • 366 citations

Inhibition of rat arterial smooth muscle cell proliferation by heparin. II. In vitro studies.

1980 • 337 citations

Inhibition of vascular smooth muscle cell growth by endothelial cell-derived heparin. Possible role of a platelet endoglycosidase.

1982 • 312 citations

Binding and internalization of heparin by vascular smooth muscle cells

1985 • 298 citations

Behavior of myc and ras oncogenes in transformation of rat embryo fibroblasts.

1986 • 272 citations

A v-myc-immortalized sympathoadrenal progenitor cell line in which neuronal differentiation is initiated by FGF but not NGF

1990 • 205 citations

Recombinant retroviruses encoding simian virus 40 large T antigen and polyomavirus large and middle T antigens.

1986 • 178 citations

Heparin selectively inhibits a protein kinase C-dependent mechanism of cell cycle progression in calf aortic smooth muscle cells [published erratum appears in J Cell Biol 1990 Mar;110(3):863]

1989 • 170 citations

Heparin inhibits c-fos and c-myc mRNA expression in vascular smooth muscle cells.

1990 • 124 citations

The large tumor antigen of simian virus 40 encodes at least two distinct transforming functions

1989 • 117 citations

Polyomavirus small t antigen: overproduction in bacteria, purification, and utilization for monoclonal and polyclonal antibody production

1986 • 114 citations

A recombinant murine retrovirus for simian virus 40 large T cDNA transforms mouse fibroblasts to anchorage-independent growth

1986 • 101 citations

Dissociation of Rb-binding and anchorage-independent growth from immortalization and tumorigenicity using SV40 mutants producing N-terminally truncated large T antigens

1990 • 95 citations

Recombinant retroviruses that transduce individual polyoma tumor antigens: effects on growth and differentiation.

1986 • 93 citations

Identification of a region of simian virus 40 large T antigen required for cell transformation

1990 • 90 citations

Unusual lysosomes in aortic smooth muscle cells: presence in living and rapidly frozen cells.

1986 • 75 citations

Sequences from polyomavirus and simian virus 40 large T genes capable of immortalizing primary rat embryo fibroblasts

1985 • 74 citations

Heparin binding, internalization, and metabolism in vascular smooth muscle cells: I. Upregulation of heparin binding correlates with antiproliferative activity

1995 • 71 citations

A retrovirus expressing the 12S adenoviral E1A gene product can immortalize epithelial cells from a broad range of rat tissues.

1988 • 64 citations

Rat vascular smooth muscle cells immortalized with SV40 large T antigen possess defined smooth muscle cell characteristics including growth inhibition by heparin

1990 • 58 citations