Back to search

Selective regulation by δ-PKC and PI 3-kinase in the assembly of the antiapoptotic TNFR-1 signaling complex in neutrophils

Data up to Jan 2025

Published2004
Citations56
References70

Total Citations Per Year

Abstract

References (70)

Isolation of mononuclear cells and granulocytes from human blood.

1968 • 9,672 citations

Death Receptors: Signaling and Modulation

1998 • 5,873 citations

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

1968 • 5,084 citations

Nuclear Factor-κB — A Pivotal Transcription Factor in Chronic Inflammatory Diseases

1997 • 4,661 citations

Phosphorylation Meets Ubiquitination: The Control of NF-κB Activity

2000 • 4,644 citations

Specificity and mechanism of action of some commonly used protein kinase inhibitors

2000 • 4,109 citations

NF-κB: Ten Years After

1996 • 3,008 citations

Specificity and mechanism of action of some commonly used protein kinase inhibitors

2000 • 3,002 citations

Induction of TNF Receptor I-Mediated Apoptosis via Two Sequential Signaling Complexes

2003 • 2,545 citations

Involvement of MACH, a Novel MORT1/FADD-Interacting Protease, in Fas/APO-1- and TNF Receptor–Induced Cell Death

1996 • 2,306 citations

The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation

1995 • 1,979 citations

TRADD–TRAF2 and TRADD–FADD Interactions Define Two Distinct TNF Receptor 1 Signal Transduction Pathways

1996 • 1,976 citations

TNF-R1 Signaling: A Beautiful Pathway

2002 • 1,860 citations

Signal transduction by tumor necrosis factor and its relatives

2001 • 1,623 citations

TUMOR NECROSIS FACTOR RECEPTOR AND Fas SIGNALING MECHANISMS

1999 • 1,309 citations

TNF-Dependent Recruitment of the Protein Kinase RIP to the TNF Receptor-1 Signaling Complex

1996 • 1,154 citations

Protein Kinase C Isotypes Controlled by Phosphoinositide 3-Kinase Through the Protein Kinase PDK1

1998 • 1,118 citations

Modulation of granulocyte survival and programmed cell death by cytokines and bacterial products

1992 • 1,103 citations

The Death Domain Kinase RIP Mediates the TNF-Induced NF-κB Signal

1998 • 1,062 citations

A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor

1994 • 1,043 citations

Using Antibodies: A Laboratory Manual

1998 • 1,012 citations

Molecular cloning and expression of a receptor for human tumor necrosis factor

1990 • 973 citations

RIP: A novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death

1995 • 964 citations

Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor

1990 • 918 citations

Neutrophil activation on biological surfaces. Massive secretion of hydrogen peroxide in response to products of macrophages and lymphocytes.

1987 • 823 citations

Inhibition of apoptosis and prolongation of neutrophil functional longevity by inflammatory mediators

1993 • 726 citations

Cytokine-induced respiratory burst of human neutrophils: dependence on extracellular matrix proteins and CD11/CD18 integrins.

1989 • 577 citations

Activation of protein kinase C family members by the novel polyphosphoinositides PtdIns-3,4-P2 and PtdIns-3,4,5-P3.

1994 • 553 citations

RIP mediates tumor necrosis factor receptor 1 activation of NF-kappaB but not Fas/APO-1-initiated apoptosis.

1996 • 540 citations

Opposing cardioprotective actions and parallel hypertrophic effects of δPKC and ɛPKC

2001 • 540 citations

Molecular control of neutrophil apoptosis

2001 • 484 citations

Recruitment of the IKK Signalosome to the p55 TNF Receptor

2000 • 457 citations

The Distinct Roles of TRAF2 and RIP in IKK Activation by TNF-R1

2000 • 429 citations

The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex

1996 • 415 citations

Neutrophil Apoptosis in the Acute Respiratory Distress Syndrome

1997 • 394 citations

TNF ligands and receptors – a matter of life and death

2002 • 376 citations

Inhibition of TNF-induced apoptosis by NF-κB

1998 • 370 citations

Dysregulated Expression of Neutrophil Apoptosis in the Systemic Inflammatory Response Syndrome

1997 • 336 citations

Regulation of Neutrophil Apoptosis by Tumor Necrosis Factor-α: Requirement for TNFR55 and TNFR75 for Induction of Apoptosis In Vitro

1997 • 296 citations

Interleukin-10 Counterregulates Proinflammatory Cytokine-Induced Inhibition of Neutrophil Apoptosis During Severe Sepsis

1997 • 294 citations

Involvement of regulatory and catalytic subunits of phosphoinositide 3-kinase in NF-κB activation

1999 • 285 citations

Granulocyte-Macrophage Colony-Stimulating Factor Delays Neutrophil Constitutive Apoptosis Through Phosphoinositide 3-Kinase and Extracellular Signal-Regulated Kinase Pathways

2000 • 262 citations

The p60 Tumor Necrosis Factor (TNF) Receptor-associated Kinase (TRAK) Binds Residues 344–397 within the Cytoplasmic Domain Involved in TNF Signaling

1995 • 234 citations

Phosphatidylinositol 3-Kinase in Interleukin 1 Signaling

1997 • 231 citations

Tumour necrosis factors receptor associated signalling molecules and their role in activation of apoptosis, JNK and NF-kappa B

2000 • 228 citations

Fas-associated Death Domain Protein and Caspase-8 Are Not Recruited to the Tumor Necrosis Factor Receptor 1 Signaling Complex during Tumor Necrosis Factor-induced Apoptosis

2003 • 209 citations

Cooperative Regulation of Mcl-1 by Janus Kinase/STAT and Phosphatidylinositol 3-Kinase Contribute to Granulocyte-Macrophage Colony-Stimulating Factor-Delayed Apoptosis in Human Neutrophils

2001 • 180 citations

Integrin-mediated Signaling Events in Human Endothelial Cells

1998 • 164 citations

The α and β Subunits of IκB Kinase (IKK) Mediate TRAF2-Dependent IKK Recruitment to Tumor Necrosis Factor (TNF) Receptor 1 in Response to TNF

2001 • 149 citations

Divergent effects of tumor necrosis factor alpha on apoptosis of human neutrophils.

2001 • 145 citations

Circulating Mediators in Serum of Injured Patients with Septic Complications Inhibit Neutrophil Apoptosis through Up-regulation of Protein-Tyrosine Phosphorylation

1998 • 119 citations

NF-κB Activation in Tumor Necrosis Factor α-stimulated Neutrophils Is Mediated by Protein Kinase Cδ

2001 • 117 citations

Divergent effects of tumor necrosis factor α on apoptosis of human neutrophils

2001 • 115 citations

Role of PI3-kinase–dependent Bad phosphorylation and altered transcription in cytokine-mediated neutrophil survival

2002 • 115 citations

Apoptosis in sepsis

2000 • 111 citations

TNFα-INDUCED SUPPRESSION OF PMN APOPTOSIS IS MEDIATED THROUGH INTERLEUKIN-8 PRODUCTION

2000 • 97 citations

A role for PKC-δ and PI 3-kinase in TNF-α-mediated antiapoptotic signaling in the human neutrophil

2002 • 86 citations

Protein Kinase C δ Specifically Associates with Phosphatidylinositol 3-Kinase Following Cytokine Stimulation

1996 • 84 citations

Crosstalk between NF-κB-Activating and Apoptosis-Inducing Proteins of the TNF-Receptor Complex

2001 • 79 citations

Phosphatidylinositol 3‐kinase is recruited to a specific site in the activated IL‐1 receptor I

1998 • 75 citations

Phosphorylation of Tumor Necrosis Factor Receptor CD120a (p55) by p42 Induces Changes in Its Subcellular Localization

1999 • 60 citations

Guanidinoethyl sulphonate is a glycine receptor antagonist in striatum

2002 • 59 citations

Critical Role of the Carboxyl Terminus of Proline-rich Tyrosine Kinase (Pyk2) in the Activation of Human Neutrophils by Tumor Necrosis Factor

2002 • 51 citations

TNF receptor signal transduction. Ligand-dependent stimulation of a serine protein kinase activity associated with (CD120a) TNFR60.

1994 • 48 citations

Serine phosphorylation of p60 tumor necrosis factor receptor by PKC-δ in TNF-α-activated neutrophils

2000 • 39 citations

INHIBITED NEUTROPHIL APOPTOSIS: PROTEASOME DEPENDENT NF-κB TRANSLOCATION IS REQUIRED FOR TRAF-1 SYNTHESIS

2000 • 36 citations

Granulocyte macrophage-colony stimulating factor delays neutrophil apoptosis and primes its function through Ia-type phosphoinositide 3-kinase

2002 • 35 citations

Differential involvement of p38 mitogen-activated protein kinase and phosphatidyl inositol 3-kinase in the IL-1-mediated NF-κB and AP-1 activation

2001 • 33 citations

Heterogeneity in the Phosphorylation of Human Death Receptors by p42mapk/erk2

2001 • 16 citations

TNFα Elicits Association of PI 3-Kinase with the p60TNFR and Activation of PI 3-Kinase in Adherent Neutrophils

2001 • 15 citations

Cited By (0)

No citing papers found in database

Selective regulation by δ-PKC and PI 3-kinase in the assembly of the antiapoptotic TNFR-1… (2004) – AJP Cell Physiology | Metascience Observatory Explorer