Germline Organization of the Murine T Cell Receptor β-Chain Genes

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Somatic generation of antibody diversity

1983 • 3,275 citations

Electrophoretic Separations of Large DNA Molecules by Periodic Inversion of the Electric Field

1986 • 920 citations

The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody.

1983 • 861 citations

Clonotypic structures involved in antigen-specific human T cell function. Relationship to the T3 molecular complex.

1983 • 833 citations

The Molecular Genetics of the T-Cell Antigen Receptor and T-Cell Antigen Recognition

1986 • 772 citations

Preferential utilization of the most JH-proximal VH gene segments in pre-B-cell lines

1984 • 644 citations

Tumor-specific antigen of murine T-lymphoma defined with monoclonal antibody.

1982 • 526 citations

Somatic recombination in a murine T-cell receptor gene

1984 • 468 citations

Introduced T cell receptor variable region gene segments recombine in pre-B cells: Evidence that B and T cells use a common recombinase

1986 • 452 citations

A T cell receptor Vβ segment that imparts reactivity to a class II major histocompatibility complex product

1987 • 408 citations

Mouse T cell antigen receptor: Structure and organization of constant and joining gene segments encoding the β polypeptide

1984 • 407 citations

Regulation of the Assembly and Expression of Variable-Region Genes

1986 • 402 citations

Genomic organization and sequence of T-cell receptor β-chain constant- and joining-region genes

1984 • 377 citations

Developmentally Controlled Expression of Immunoglobulin V _H Genes

1985 • 349 citations

Identification of D segments of immunoglobulin heavy-chain genes and their rearrangement in T lymphocytes

1981 • 327 citations

The human t cell antigen receptor is encoded by variable, diversity, and joining gene segments that rearrange to generate a complete V gene

1984 • 306 citations

Murine T-cell receptor mutants with deletions of beta-chain variable region genes.

1986 • 304 citations

The murine T-cell receptor uses a limited repertoire of expressed Vβ gene segments

1985 • 283 citations

Novel immunoglobulin heavy chains are produced from DJH gene segment rearrangements in lymphoid cells

1984 • 261 citations

Structure, expression and divergence of T-cell receptor β-chain variable regions

1984 • 237 citations

Rearrangement of T-cell receptor beta-chain genes during T-cell development.

1985 • 200 citations

T-Cell Receptor β-Chain Expression: Dependence on Relatively Few Variable Region Genes

1985 • 197 citations

Molecular map of the murine S region.

1983 • 185 citations

Localization of a T-cell receptor diversity-region element

1984 • 159 citations

T cell-specific gamma genes in C57BL/10 mice. Sequence and expression of new constant and variable region genes.

1986 • 154 citations

Direct evidence for chromosomal inversion during T-cell receptor β-gene rearrangements

1986 • 151 citations

T cell receptor β gene sequences in the circular DNA of thymocyte nuclei: Direct evidence for intramolecular DNA deletion in V-D-J joining

1987 • 144 citations

VH gene family utilization in colonies derived from B and pre-B cells detected by the RNA colony blot assay.

1986 • 127 citations

Isolation of an excision product of T-cell receptor α-chain gene rearrangments

1987 • 124 citations

Identification of a diversity segment of human T-cell receptor β-chain, and comparison with the analogous murine element

1984 • 121 citations

Rearranged β t cell receptor genes in a helper t cell clone specific for lysozyme: No correlation between Vβ and MHC restriction

1985 • 120 citations

[35] Strategies for mapping and cloning macroregions of mammalian genomes

1987 • 112 citations

Tandem linkage and unusual RNA splicing of the T-cell receptor beta-chain variable-region genes.

1987 • 105 citations

Clonal diversity and T-cell receptor beta-chain variable gene expression in enlarged lymph nodes of MRL-lpr/lpr lupus mice.

1986 • 96 citations

T cell receptor genes in an alloreactive CTL clone: implications for rearrangement and germline diversity of variable gene segments.

1986 • 82 citations

Vβ gene polymorphism and a major polyclonal T cell receptor idiotype

1985 • 75 citations

Expression of a murine polyclonal T cell receptor marker correlates with the use of specific members of the V beta 8 gene segment subfamily.

1987 • 73 citations

T-cell receptor variable region gene usage in T-cell populations.

1986 • 59 citations

Continuing rearrangement of immunoglobulin and T-cell receptor genes in a Ha-ras-transformed lymphoid progenitor cell line.

1987 • 38 citations