Histochemical detection of 4-hydroxynonenal protein in Alzheimer amyloid

[30] Microsomal lipid peroxidation

1978 • 12,818 citations

[49] Determination of carbonyl content in oxidatively modified proteins

1990 • 5,654 citations

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD)

1991 • 4,669 citations

Identification of 4-hydroxynonenal as a cytotoxic product originating from the peroxidation of liver microsomal lipids

1980 • 1,094 citations

Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease.

1996 • 976 citations

Role of xanthine oxidase and granulocytes in ischemia-reperfusion injury

1988 • 794 citations

β-Amyloid-mediated vasoactivity and vascular endothelial damage

1996 • 686 citations

Proof of Efficacy of the Ginkgo Biloba Special Extract EGb 761 in Outpatients Suffering from Mild to Moderate Primary Degenerative Dementia of the Alzheimer Type or Multi-infarct Dementia

1996 • 377 citations

Amyloid peptides are toxic via a common oxidative mechanism.

1995 • 372 citations

Expression of heme oxygenase‐1 in the senescent and alzheimer‐diseased brain

1995 • 352 citations

Formation of 4-hydroxy-2-nonenal-modified proteins in the renal proximal tubules of rats treated with a renal carcinogen, ferric nitrilotriacetate.

1994 • 337 citations

Accuracy of the clinical diagnosis of vascular dementia: a prospective clinical and post-mortem neuropathological study.

1988 • 223 citations

Immunohistochemical detection of 4-hydroxy-2-nonenal adducts in Alzheimer's disease is associated with inheritance of APOE4.

1997 • 219 citations

Electron micrograph of diffuse plaques. Initial stage of senile plaque formation in the Alzheimer brain.

1989 • 140 citations

Characterization of Epitopes Recognized by 4-Hydroxy-2-nonenal Specific Antibodies

1995 • 138 citations

Oxidative Stress Is Found in Amyloid Deposits in Systemic Amyloidosis

1997 • 134 citations

Transthyretin and Familial Amyloidotic Polyneuropathy.

1993 • 90 citations

Structural modifications of human β2 microglobulin treated with oxygen-derived radicals

1991 • 81 citations

Fluorescent light-induced chromatid breaks distinguish Alzheimer disease cells from normal cells in tissue culture.

1996 • 62 citations

Inhibition of lipid peroxidation by superoxide dismutase following regional intestinal ischemia and reperfusion

1987 • 57 citations

Migration of perivascular cells into the neuropil and their involvement in ?-amyloid plaque formation

1993 • 55 citations

Transduction in Group A streptococcus

1968 • 44 citations

Oxidation of LDL: Role in atherogenesis

1991 • 32 citations

Neutrophil Proteases Associated with Amyloid Fibrils

1993 • 25 citations

Radical Formation in the Rat Small Intestine During and Following Ischemia

1989 • 25 citations

The Association of an Elastase with Amyloid Fibrils

1986 • 25 citations

Effects of the lipid peroxidation product 4-hydroxynonenal on the aggregation of human platelets

1987 • 14 citations