Expression of heme oxygenase‐1 in the senescent and alzheimer‐diseased brain

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Lounging in a lysosome: the intracellular lifestyle of Coxiella burnetii

2007 • 11,720 citations

Bilirubin Is an Antioxidant of Possible Physiological Importance

1987 • 3,406 citations

The molecular pathology of Alzheimer's disease

1991 • 2,603 citations

Diagnosis of Alzheimer's Disease

1985 • 2,482 citations

Carbon Monoxide: a Putative Neural Messenger

1993 • 1,519 citations

Microsomal Heme Oxygenase

1969 • 1,348 citations

Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite.

1989 • 1,273 citations

A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease.

1994 • 1,085 citations

Heat shock, stress proteins, chaperones, and proteotoxicity

1991 • 1,069 citations

Stress, the Aging Brain, and the Mechanisms of Neuron Death

1992 • 788 citations

Protein A, avidin, and biotin in immunohistochemistry.

1981 • 650 citations

Induction of heme oxygenase: a general response to oxidant stress in cultured mammalian cells.

1991 • 635 citations

Nitric Oxide And Carbon Monoxide Produce Activity-Dependent Long-Term Synaptic Enhancement in Hippocampus

1993 • 562 citations

Selective accumulation of aluminum and iron in the neurofibrillary tangles of Alzheimer's disease: A laser microprobe (LAMMA) study

1992 • 474 citations

Autopsy Samples of Alzheimer's Cortex Show Increased Peroxidation In Vitro

1990 • 456 citations

Does carbon monoxide have a physiological function?

1991 • 425 citations

Transcriptional control of rat heme oxygenase by heat shock.

1987 • 415 citations

β-Amyloid Peptide Free Radical Fragments Initiate Synaptosomal Lipoperoxidation in a Sequence-Specific Fashion: Implications to Alzheimer′s Disease

1994 • 406 citations

Identification, transmembrane orientation and biogenesis of the amyloid A4 precursor of Alzheimer's disease.

1988 • 392 citations

Induction of Haem Oxygenase as a Defence Against Oxidative Stress

1990 • 322 citations

Molecular determinants of protein half‐lives in eukaryotic cells

1987 • 268 citations

Rapid induction of heme oxygenase 1 mRNA and protein by hyperthermia in rat brain: heme oxygenase 2 is not a heat shock protein.

1991 • 267 citations

Reversal of long-term potentiation by inhibitors of haem oxygenase

1993 • 265 citations

Activation of heat-shock genes in eukaryotes

1985 • 263 citations

Cobalt Induction of Hepatic Heme Oxygenase; with Evidence That Cytochrome P -450 Is Not Essential for This Enzyme Activity

1974 • 261 citations

Lipid Peroxidation and Free Radical Scavengers in Alzheimer’s Disease

1989 • 250 citations

Both near ultraviolet radiation and the oxidizing agent hydrogen peroxide induce a 32-kDa stress protein in normal human skin fibroblasts.

1987 • 225 citations

Normal and Heat‐Induced Patterns of Expression of Heme Oxygenase‐1 (HSP32) in Rat Brain: Hyperthermia Causes Rapid Induction of mRNA and Protein

1992 • 195 citations

Superoxide dismutase activity in Alzheimer's disease: possible mechanism for paired helical filament formation

1989 • 193 citations

Selective increase in lipid peroxidation in the inferior temporal cortex in Alzheimer's disease

1994 • 166 citations

Increased synthesis and accumulation of heat shock 70 proteins in Alzheimer's disease

1991 • 128 citations

Ballooned neurons in several neurodegenerative diseases and stroke contain αB crystallin

1992 • 108 citations

Immunochemical identification of ubiquitin and heat-shock proteins in corpora amylacea from normal aged and Alzheimer's disease brains

1993 • 91 citations

Brain ubiquitin is markedly elevated in Alzheimer disease

1991 • 86 citations

Heme oxygenase is a heat shock protein and PEST protein in rat astroglial cells

1992 • 84 citations

Blood Activity of Cu/Zn Superoxide Dismutase, Glutathione Peroxidase and Catalase in Alzheimer’s Disease: A Case-Control Study

1990 • 83 citations

Iron in the brain: implications for Parkinson's and Alzheimer's diseases.

1988 • 71 citations

Increased expression of heat-shock protein 27 kDa in Alzheimer disease

1993 • 62 citations

Oxidative Stress and Heat Shock Protein Induction in Human Cells

1987 • 58 citations

Localization and quantitation of 68 kDa neurofilament and superoxide dismutase-1 mRNA in alzheimer brains

1991 • 54 citations

Glial peroxidase activity in the hypothalamic arcuate nucleus: effects of estradiol valerate-induced persistent estrus

1990 • 52 citations

Carbon monoxide modulates secretion of corticotropin-releasing factor from rat hypothalamic cell cultures

1994 • 41 citations

Involvement of Carbon Monoxide in Long-Term Potentiation in the Dentate Gyrus of Anesthetized Rats

1994 • 24 citations

Does endogenous zinc protoporphyrin modulate carbon monoxide formation from heme? Implications for long-term potentiation, memory, and cognitive function

1993 • 18 citations

The role of heme oxygenase and aryl hydrocarbon hydroxylase in the protection by cysteamine from acetaminophen hepatotoxicity

1989 • 14 citations

Neurodegenerative disease

2002 • 6 citations