Keratinocyte-derived tumor necrosis factor and the physiopathology of the skin

The Biology of Cachectin/TNF -- A Primary Mediator of the Host Response

1989 • 1,679 citations

Interleukin-1 and Its Biologically Related Cytokines

1989 • 1,180 citations

Tumour necrosis factor as immunomodulator and mediator of monocyte cytotoxicity induced by itself, γ-interferon and interleukin-1

1986 • 781 citations

Blocking IL-1: interleukin 1 receptor antagonist in vivo and in vitro

1991 • 729 citations

Human keratinocytes are a source for tumor necrosis factor alpha: evidence for synthesis and release upon stimulation with endotoxin or ultraviolet light.

1990 • 707 citations

Warner-Lambert/Parke-Davis award lecture. Cytokine-mediated activation of vascular endothelium. Physiology and pathology.

1988 • 597 citations

Localization of antigen on lymph node dendritic cells after exposure to the contact sensitizer fluorescein isothiocyanate. Functional and morphological studies.

1987 • 592 citations

Immunoregulatory activity of recombinant human tumor necrosis factor (TNF)-alpha: induction of TNF receptors on human T cells and TNF-alpha-mediated enhancement of T cell responses.

1987 • 490 citations

Epidermal cell (keratinocyte)-derived thymocyte-activating factor (ETAF).

1981 • 420 citations

Prevention of diabetes in nonobese diabetic mice by tumor necrosis factor (TNF): similarities between TNF-alpha and interleukin 1.

1990 • 356 citations

Cytokine Modulation of Keratinocyte Cytokines

1990 • 345 citations

Tumor necrosis factor is a critical mediator in hapten induced irritant and contact hypersensitivity reactions.

1991 • 341 citations

Epidermal Cell Production of Thymocyte Activating Factor (ETAF)

1982 • 319 citations

The antitumor function of tumor necrosis factor (TNF), I. Therapeutic action of TNF against an established murine sarcoma is indirect, immunologically dependent, and limited by severe toxicity.

1988 • 276 citations

Effect of tumor necrosis factor alpha on mitogen-activated human B cells.

1987 • 245 citations

Recombinant soluble tumor necrosis factor receptor proteins protect mice from lipopolysaccharide‐induced lethality

1991 • 239 citations

Regulation of Alloreactivity in Vivo by a Soluble Form of the Interleukin-1 Receptor

1990 • 235 citations

Interleukin 1 is present in normal human epidermis.

1986 • 214 citations

Pretreatment with recombinant murine tumor necrosis factor alpha/cachectin and murine interleukin 1 alpha protects mice from lethal bacterial infection.

1989 • 196 citations

ELICITATION OF DELAYED ALLERGIC SKIN REACTIONS WITH HAPTENS: THE DEPENDENCE OF ELICITATION ON HAPTEN COMBINATION WITH PROTEIN

1952 • 188 citations

Relationship between epidermal Langerhans cell density ATPase activity and the induction of contact hypersensitivity.

1981 • 180 citations

The Common Mediator of Shock, Cachexia, and Tumor Necrosis

1988 • 175 citations

Keratinocyte intercellular adhesion molecule-1 (ICAM-1) expression precedes dermal T lymphocytic infiltration in allergic contact dermatitis (Rhus dermatitis).

1989 • 150 citations

Subcutaneous perfusion of tumor necrosis factor induces local proliferation of fibroblasts, capillaries, and epidermal cells, or massive tissue necrosis.

1990 • 147 citations

Chemical Treatment of Tumors. IX. Reactions of Mice with Primary Subcutaneous Tumors to Injection of a Hemorrhage-Producing Bacterial Polysaccharide<xref ref-type="fn" rid="fn1"><sup>1</sup></xref>

1944 • 133 citations

Unequivocal Delayed Hypersensitivity in Mast Cell-Deficient and Beige Mice

1984 • 121 citations

Genetic basis of ultraviolet-B effects on contact hypersensitivity

1988 • 114 citations

The involvement of human tumor necrosis factors-alpha and -beta in the mixed lymphocyte reaction.

1988 • 111 citations

Tumor necrosis factor expression in human epithelial tumor cell lines.

1988 • 102 citations

Long-term inhibition of tumor growth by tumor necrosis factor in the absence of cachexia or T-cell immunity.

1991 • 99 citations

Effects of recombinant murine tumor necrosis factor-alpha on immune function.

1990 • 89 citations

In Vivo Administration of Interleukin 1 to Normal Mice Depresses Their Capacity to Elicit Contact Hypersensitivity Responses: Prostaglandins Are Involved in This Modification of Immune Function

1987 • 87 citations

Effect of a single exposure to ultraviolet radiation on Mycobacterium bovis bacillus Calmette-Guerin infection in mice.

1989 • 84 citations

A Comparative Light and Electron Microscopic Study of Primary Irritant Contact Dermatitis and Allergic Contact Dermatitis

1971 • 82 citations

55-kd Tumor Necrosis Factor Receptor Is Expressed by Human Keratinocytes and Plays a Pivotal Role in Regulation of Human Keratinocyte ICAM-1 Expression

1991 • 78 citations

Autocrine Stimulation of Interleukin-1α and Transforming Growth Factorα Production in Human Keratinocytes and Its Antagonism by Glucocorticoids

1991 • 76 citations

Alternative Cleavage of the Cachectin/Tumor Necrosis Factor Propeptide Results in a Larger, Inactive Form of Secreted Protein

1989 • 75 citations

Tumor necrosis factor-alpha and ultraviolet B light have similar effects on contact hypersensitivity in mice.

1990 • 64 citations

CELLULAR AND VASCULAR COMPONENTS OF ALLERGIC CONTACT DERMATITIS.

1963 • 63 citations

Cytotoxicity of tumor necrosis factor-alpha for human umbilical vein endothelial cells.

1989 • 61 citations

Enhancement of in vivo immune response by tumor necrosis factor.

1987 • 59 citations

Ratio of Langerhans Cells to Thy-1+ Dendritic Epidermal Cells in Murine Epidermis Influences the Intensity of Contact Hypersensitivity

1987 • 47 citations

Sequential immunophenotypic study of lymphoid infiltrate in allergic and irritant reactions

1987 • 43 citations

Expression of the tumor necrosis factor gene in tumor cells correlates with reduced tumorigenicity and reduced invasiveness in vivo.

1991 • 42 citations

The cellular infiltrate in contact hypersensitivity to picryl chloride in the mouse

1979 • 41 citations

Cytotoxicity of tumor necrosis factor for thyroid epithelial cells and its regulation by interferon‐γ

1987 • 39 citations

Interleukin 1 receptor antagonist in human epidermis and cultured keratinocytes

1991 • 38 citations

Activation of the IL-1 Gene in UV-Irradiated Mouse Skin: Association with Inflammatory Sequelae and Pharmacologic Intervention

1991 • 32 citations

Tumor necrosis factor and immunopathology

1991 • 27 citations

Value of the Cutaneous Basophil Hypersensitivity (CBH) Response for Distinguishing Weak Contact Sensitization from Irritation Reactions in the Guinea Pig

1990 • 22 citations

Hematopoietic Tissue in Malaria: Facilitation of Erythrocytic Recycling by Bone Marrow in Plasmodium berghei-Infected Mice

1983 • 22 citations

SUPPRESSION OF EPIDERMAL GRAFT-VERSUS-HOST DISEASE WITH ULTRAVIOLET RADIATION

1984 • 19 citations

Development of Natural Killer Cells: Comparison of the Maturation Rates in Different Lymphoid Compartments

1985 • 5 citations