Long-term inhibition of tumor growth by tumor necrosis factor in the absence of cachexia or T-cell immunity.

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1983 • 52,849 citations

Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.

1987 • 4,937 citations

An endotoxin-induced serum factor that causes necrosis of tumors.

1975 • 4,522 citations

Identity of tumour necrosis factor and the macrophage-secreted factor cachectin

1985 • 1,125 citations

Cachectin/tumor necrosis factor induces cachexia, anemia, and inflammation.

1988 • 745 citations

Tumors secreting human TNF/cachectin induce cachexia in mice

1987 • 634 citations

Peptide Regulatory Factors

1989 • 498 citations

Shedding of tumor necrosis factor receptors by activated human neutrophils.

1990 • 443 citations

Tumor necrosis factor: a potent effector molecule for tumor cell killing by activated macrophages.

1986 • 360 citations

The antitumor function of tumor necrosis factor (TNF), I. Therapeutic action of TNF against an established murine sarcoma is indirect, immunologically dependent, and limited by severe toxicity.

1988 • 276 citations

Anticachectin/tumor necrosis factor‐α antibodies attenuate development of cachexia in tumor models

1989 • 210 citations

The antitumor function of tumor necrosis factor (TNF) II. Analysis of the role of endogenous TNF in endotoxin-induced hemorrhagic necrosis and regression of an established sarcoma.

1988 • 83 citations

Monoclonal Antibodies to Human Tumor Necrosis Factors Alpha and Beta: Application for Affinity Purification, Immunoassays, and as Structural Probes

1987 • 63 citations

Identification of a unique tumor antigen as rejection antigen by molecular cloning and gene transfer.

1986 • 44 citations

Impact of tolerance on antitumor efficacy of tumor necrosis factor in mice.

1990 • 19 citations

Endogenous cachectin/tumour necrosis factor-alpha production contributes to experimental cancer-associated cachexia.

1989 • 9 citations