Effects of calcium binding on the internal dynamic properties of bovine brain calmodulin, studied by NMR and optical spectroscopy

Methods of Enzymatic Analysis

1975 • 20,446 citations

Model-free approach to the interpretation of nuclear magnetic resonance relaxation in macromolecules. 1. Theory and range of validity

1982 • 3,662 citations

MLEV-17-based two-dimensional homonuclear magnetization transfer spectroscopy

1985 • 3,603 citations

Model-free approach to the interpretation of nuclear magnetic resonance relaxation in macromolecules

1982 • 2,524 citations

Estimation of globular protein secondary structure from circular dichroism

1981 • 2,139 citations

Carp Muscle Calcium-binding Protein

1973 • 1,359 citations

Three-dimensional structure of calmodulin

1985 • 1,035 citations

Structure of calmodulin refined at 2.2 Å resolution

1988 • 1,019 citations

A theory of fluorescence polarization decay in membranes

1977 • 903 citations

Ca2+-induced hydrophobic site on calmodulin: Application for purification of calmodulin by phenyl-Sepharose affinity chromatography

1982 • 877 citations

How calmodulin binds its targets: sequence independent recognition of amphiphilic α-helices

1990 • 839 citations

A novel approach for sequential assignment of proton, carbon-13, and nitrogen-15 spectra of larger proteins: heteronuclear triple-resonance three-dimensional NMR spectroscopy. Application to calmodulin

1990 • 836 citations

Conformational transition accompanying the binding of calcium(2+) ion to the protein activator of 3',5'-cyclic adenosine monophosphate phosphodiesterase

1977 • 472 citations

Refinement of the structure of carp muscle calcium-binding parvalbumin by model building and difference fourier analysis

1975 • 433 citations

Truncated driven nuclear overhauser effect (TOE). A new technique for studies of selective 1H1H overhauser effects in the presence of spin diffusion

1979 • 355 citations

Refined crystal structure of troponin C from turkey skeletal muscle at 2·0 Å resolution

1988 • 335 citations

Comparison of the crystal and solution structures of calmodulin and troponin C

1988 • 322 citations

Effects of cations on affinity of calmodulin for calcium: ordered binding of calcium ions allows the specific activation of calmodulin-stimulated enzymes. Theoretical approach to study of multiple ligand binding to a macromolecule

1981 • 321 citations

Theoretical CD studies of polypeptide helices: Examination of important electronic and geometric factors

1991 • 320 citations

Circular dichroism studies of distorted α-helices, twisted β-sheets, and β-turns

1988 • 282 citations

Refined structure of chicken skeletal muscle troponin C in the two-calcium state at 2-A resolution.

1988 • 279 citations

Calmodulins from Muscles of Marine Invertebrates, Scallop and Sea Anemone

1980 • 276 citations

The central helix of calmodulin functions as a flexible tether.

1988 • 245 citations

Hydrodynamic properties of macromolecular complexes. I. Translation

1977 • 225 citations

Alamethicin, a transmembrane channel

1981 • 216 citations

Calcium- and magnesium-dependent conformational states of calmodulin as determined by nuclear magnetic resonance

1980 • 204 citations

Agonist and antagonist properties of calmodulin fragments.

1984 • 198 citations

Crystal structure of calmodulin

1986 • 149 citations

Triple-resonance multidimensional NMR study of calmodulin complexed with the binding domain of skeletal muscle myosin light-chain kinase: indication of a conformational change in the central helix

1991 • 143 citations

Melittin binding causes a large calcium-dependent conformational change in calmodulin.

1989 • 141 citations

Kinetics of calcium dissociation from calmodulin and its tryptic fragments. A stopped-flow fluorescence study using Quin 2 reveals a two-domain structure

1985 • 137 citations

α-Proton chemical shifts and secondary structure in proteins

1989 • 131 citations

Molecular interactions and structure as analysed by fluorescence relaxation spectroscopy

1973 • 125 citations

Metal ion and drug binding to proteolytic fragments of calmodulin: proteolytic cadmium-113 and proton nuclear magnetic resonance studies

1984 • 125 citations

Changes in the structure of calmodulin induced by a peptide based on the calmodulin-binding domain of myosin light chain kinase

1989 • 118 citations

HMQC-NOESY-HMQC, a three-dimensional NMR experiment which allows detection of nuclear overhauser effects between protons with overlapping signals

1990 • 104 citations

¹H‐NMR studies of calmodulin

1984 • 103 citations

Tyrosine fluorescence of ram testis and octopus calmodulins. Effects of calcium, magnesium, and ionic strength

1981 • 97 citations

Time development of proton nuclear overhauser effects in proteins

1982 • 95 citations

Calmodulin and troponin C structures studied by Fourier transform infrared spectroscopy: effects of calcium and magnesium binding

1989 • 93 citations

Photolabeling of Calmodulin with Basic, Amphiphilic α-Helical Peptides Containing p-Benzoylphenylalanine

1989 • 93 citations

¹H NMR studies of calmodulin

1984 • 93 citations

The effects of Ca2+ and Cd2+ on the secondary and tertiary structure of bovine testis calmodulin. A circular-dichroism study

1986 • 92 citations

Nuclear magnetic resonance studies on calmodulin: calcium-induced conformational change

1983 • 82 citations

Refined crystal structure of calcium-liganded carp parvalbumin 4.25 at 1.5-.ANG. resolution

1990 • 81 citations

Fluorescence anisotropy decay demonstrates calcium-dependent shape changes in photo-cross-linked calmodulin

1988 • 79 citations

Binding of Both Ca2+ and Mastoparan to Calmodulin Induces a Large Change in the Tertiary Structure

1989 • 75 citations

Small-angle scattering studies show distinct conformations of calmodulin in its complexes with two peptides based on the regulatory domain of the catalytic subunit of phosphorylase kinase

1990 • 74 citations

Nuclear magnetic resonance studies on calmodulin: calcium-dependent spectral change of proteolytic fragments

1984 • 66 citations

Hydrodynamics of macromolecular complexes. II. Rotation

1977 • 65 citations

Hydrogen bonding in the carboxyl-terminal half-fragment 78-148 of calmodulin as studied by two-dimensional nuclear magnetic resonance

1985 • 60 citations

Sequential assignment of the 1H and 31P resonances of the double stranded deoxynucleotide d(ATGCAT)2 by 2D-NMR correlation spectroscopy

1984 • 55 citations

Fluorescence and conformational changes caused by proton binding to troponin C

1974 • 45 citations

Structural characterization of the interactions between calmodulin and skeletal muscle myosin light chain kinase: effect of peptide (576-594)G binding on the calcium-binding domains

1989 • 44 citations

A method for evaluating correlation times for tumbling and internal motion in macromolecules using cross-relaxation rate constants from proton NMR spectra

1986 • 44 citations

Conformational transitions of calmodulin as studied by vacuum‐UV CD

1987 • 40 citations

Sequence‐specific assignments of downfield‐shifted amide proton resonances of calmodulin Use of two‐dimensional NMR analysis of its tryptic fragments

1987 • 36 citations

pH-dependent structural transition in rabbit skeletal troponin C.

1987 • 35 citations

Molecular dynamics of calmodulin as monitored by fluorescence anisotropy

1982 • 34 citations

The conformation of calmodulin: A substantial environmentally sensitive helical transition in Ca₄‐calmodulin with potential mechanistic function

1988 • 34 citations

Quantitative interpretation of a single NOESY spectrum

1988 • 33 citations

Nuclear magnetic resonance studies on calmodulin: spectral assignments in the calcium-free state

1983 • 29 citations

Intensity and anisotropy decays of the tyrosine calmodulin proteolytic fragments, as studied by GHz frequency-domain fluorescence

1991 • 26 citations

Kinetics of cadmium and terbium dissociation from calmodulin and its tryptic fragments

1986 • 23 citations

A study of the interactions between residues in the C‐terminal half of calmodulin by one and two‐dimensional NMR methods and computer modelling

1984 • 23 citations

Frequency-domain measurements of the rotational dynamics of the tyrosine groups of calmodulin

1988 • 18 citations

NMR studies of muscle proteins

1984 • 14 citations

The time resolved fluorescence and anisotropy of subtilisins BPN′ and Carlsberg

1991 • 13 citations

pH-dependent conformational changes of wheat germ calmodulin

1989 • 11 citations

Rotational modes of Ca2+-liganded calmodulin, as determined by time-domain fluorescence

1987 • 9 citations

[13] Preparation of calmodulin crystals

1983 • 8 citations

The influence of tryptophan on mobility of residues in the trp repressor of Escherichia coli

1989 • 7 citations