NMR evidence for multiple conformations in a highly helical model peptide

Spectroscopic Determination of Tryptophan and Tyrosine in Proteins^*

1967 • 3,423 citations

Application of phase sensitive two-dimensional correlated spectroscopy (COSY) for measurements of 1H-1H spin-spin coupling constants in proteins

1983 • 3,150 citations

Contact Electron-Spin Coupling of Nuclear Magnetic Moments

1959 • 2,920 citations

Determination of the helix and β form of proteins in aqueous solution by circular dichroism

1974 • 2,040 citations

Relationship between nuclear magnetic resonance chemical shift and protein secondary structure

1991 • 1,888 citations

In situ neutralization in Boc‐chemistry solid phase peptide synthesis

1992 • 1,038 citations

The Ultraviolet Circular Dichroism of Polypeptides¹

1965 • 1,013 citations

Helix stabilization by Glu-...Lys+ salt bridges in short peptides of de novo design.

1987 • 930 citations

Spin—spin coupling and the conformational states of peptide systems

1976 • 788 citations

Polypeptide secondary structure determination by nuclear magnetic resonance observation of short proton-proton distances

1984 • 756 citations

¹H‐nmr parameters of the common amino acid residues measured in aqueous solutions of the linear tetrapeptides H‐Gly‐Gly‐X‐<scp>L</scp>‐Ala‐OH

1979 • 750 citations

Folding of immunogenic peptide fragments of proteins in water solution

1988 • 735 citations

Sequential resonance assignments in protein 1H nuclear magnetic resonance spectra

1982 • 585 citations

Calculation of protein conformations by proton-proton distance constraints

1985 • 564 citations

Defining Solution Conformations of Small Linear Peptides

1991 • 528 citations

The Mechanism of alpha-Helix Formation by Peptides

1992 • 492 citations

Parameters of helix–coil transition theory for alanine‐based peptides of varying chain lengths in water

1991 • 490 citations

A protein structure from nuclear magnetic resonance data

1985 • 464 citations

Side Chain Contributions to the Stability of Alpha-Helical Structure in Peptides

1990 • 455 citations

Folding of immunogenic peptide fragments of proteins in water solution

1988 • 437 citations

Conformation-directing effects of a single intramolecular amide-amide hydrogen bond: variable-temperature NMR and IR studies on a homologous diamide series

1991 • 421 citations

Folding of peptide fragments comprising the complete sequence of proteins

1992 • 391 citations

Obtaining high-fidelity powder spectra in anisotropic media: Phase-cycled Hahn echo spectroscopy

1983 • 358 citations

Theoretical CD studies of polypeptide helices: Examination of important electronic and geometric factors

1991 • 320 citations

Helix-coil transition of the isolated amino terminus of ribonuclease

1971 • 310 citations

Quadrature fourier NMR detection: Simple multiplex for dual detection and discussion

1975 • 310 citations

Aromatic side-chain contribution to far-ultraviolet circular dichroism of helical peptides and its effect on measurement of helix propensities

1993 • 301 citations

Temperature dependence of amide proton chemical shifts: The secondary structures of gramicidin S and valinomycin

1969 • 299 citations

A distance geometry program for determining the structures of small proteins and other macromolecules from nuclear magnetic resonance measurements of intramolecular H-H proximities in solution

1984 • 288 citations

Circular dichroism studies of distorted α-helices, twisted β-sheets, and β-turns

1988 • 282 citations

Time-averaged nuclear overhauser effect distance restraints applied to tendamistat

1990 • 279 citations

Optical Rotation of Oriented Helices. III. Calculation of the Rotatory Dispersion and Circular Dichroism of the Alpha- and 310-Helix

1967 • 265 citations

Protein conformation and proton nuclear‐magnetic‐resonance chemical shifts

1983 • 251 citations

Solution conformation of a heptadecapeptide comprising the DNA binding helix F of the cyclic AMP receptor protein of Escherichia coli

1985 • 248 citations

Aromatic side‐chain contributions to the far ultraviolet circular dichroism of peptides and proteins

1978 • 245 citations

Molecular dynamics simulations of helix denaturation

1992 • 237 citations

The immunodominant site of a synthetic immunogen has a conformational preference in water for a type-II reverse turn

1985 • 225 citations

Molecular dynamics simulations of the unfolding of an .alpha.-helical analog of ribonuclease A S-peptide in water

1991 • 217 citations

Short alanine-based peptides may form 310-helices and not α-helices in aqueous solution

1992 • 205 citations

Nuclear magnetic resonance identification of “half-turn” and 310-helix secondary structure in rabbit liver metallothionein-2

1986 • 197 citations

Circular dichroism and conformation of unordered peptides

1992 • 193 citations

Optical activity of polypeptides and proteins

1972 • 188 citations

Circular Dichroism and Its Empirical Application to Biopolymers

1985 • 186 citations

Peptide models of protein folding initiation sites. 1. Secondary structure formation by peptides corresponding to the G- and H-helixes of myoglobin

1993 • 175 citations

The influence of long-range interactions on the structure of myoglobin

1968 • 169 citations

Measurement of vicinal couplings from cross peaks in COSY spectra

1989 • 169 citations

Conformational behavior of Escherichia coli OmpA signal peptides in membrane mimetic environments

1993 • 169 citations

Studies of synthetic helical peptides using circular dichroism and nuclear magnetic resonance

1990 • 167 citations

Relaxation-induced violations of coherence transfer selection rules in nuclear magnetic resonance

1987 • 165 citations

Relationship between amide proton chemical shifts and hydrogen bonding in amphipathic .alpha.-helical peptides

1992 • 157 citations

Side chain–backbone hydrogen bonding contributes to helix stability in peptides derived from an α‐helical region of carboxypeptidase A

1991 • 143 citations

Secondary‐structure dependent chemical shifts in proteins

1990 • 140 citations

Structural information from NMR secondary chemical shifts of peptide α C-H protons in proteins

1983 • 139 citations

Multi-conformational peptide dynamics derived from NMR data: A new search algorithm and its application to antamanide

1991 • 136 citations

Unfolding of an α‐helix in water

1991 • 134 citations

α-Proton chemical shifts and secondary structure in proteins

1989 • 131 citations

Effect of central-residue replacements on the helical stability of a monomeric peptide

1990 • 122 citations

Helix propagation in trifluoroethanol solutions

1992 • 101 citations

Baseline distortion in real-fourier-transform NMR spectra

1988 • 95 citations

Amide chemical shifts in many helices in peptides and proteins are periodic

1991 • 89 citations

A model peptide with enhanced helicity

1991 • 88 citations

Complete assignment of the 1H nuclear magnetic resonance spectrum of French bean plastocyanin

1988 • 70 citations

Periodic properties of proton conformational shifts in isolated protein helices

1992 • 52 citations

Folding of a peptide corresponding to the .alpha.-helix in bovine pancreatic trypsin inhibitor

1989 • 52 citations

Conformation of a T cell stimulating peptide in aqueous solution

1989 • 50 citations

A study of the NH NMR signals of Gly-Gly-X-Ala tetrapeptides in H2O at low temperature.

1986 • 49 citations

NMR chemical shifts: a tool to characterize distortions of peptide and protein helices

1992 • 41 citations

[6] Multiple-quantum nuclear magnetic resonance

1989 • 29 citations

Conformational properties of the isolated 1–23 fragment of human hemoglobin α-chain

1988 • 24 citations

AX3 spin system dynamics from forbidden cross peaks in double-quantum two-dimensional NMR experiments, with application to acyl carrier protein

1988 • 13 citations