Interdependence of tumor necrosis factor, prostaglandin E₂, and protein synthesis in lipopolysaccharide‐exposed rat Kupffer cells

Methods of Enzymatic Analysis

1975 • 20,446 citations

An endotoxin-induced serum factor that causes necrosis of tumors.

1975 • 4,522 citations

Control of Cachectin (Tumor Necrosis Factor) Synthesis: Mechanisms of Endotoxin Resistance

1986 • 1,305 citations

A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein: Ramifications for the complex physiology of TNF

1988 • 1,105 citations

The isolation of IgG from mammalian sera with the aid of caprylic acid

1969 • 874 citations

Prostaglandin E2 regulates macrophage-derived tumor necrosis factor gene expression.

1988 • 670 citations

Cells of the hepatic sinusoid

1989 • 589 citations

Cells of the hepatic sinusoid

1998 • 557 citations

Tumor necrosis factor-alpha stimulates hepatic lipogenesis in the rat in vivo.

1987 • 400 citations

Release of tumor necrosis factor-alpha from macrophages. Enhancement and suppression are dose-dependently regulated by prostaglandin E2 and cyclic nucleotides.

1988 • 397 citations

Cell-associated tumor necrosis factor (TNF) as a killing mechanism of activated cytotoxic macrophages.

1987 • 361 citations

Tumor necrosis factor stimulates interleukin-1 and prostaglandin E2 production in resting macrophages

1986 • 344 citations

Centrifugation: A Practical Approach

1985 • 222 citations

Tumour cell killing by tumour necrosis factor: inhibition by anaerobic conditions, free-radical scavengers and inhibitors of arachidonate metabolism.

1987 • 206 citations

9-Deoxy-delta 9, delta 12-13,14-dihydroprostaglandin D2, a metabolite of prostaglandin D2 formed in human plasma.

1984 • 160 citations

Rat hepatic sinusoidal endothelial cells in monolayer culture

1988 • 145 citations

The release of tumor necrosis factor from endotoxin-stimulated rat Kupffer cells is regulated by prostaglandin E2 and dexamethasone

1988 • 140 citations

Macrophages rapidly internalize their tumor necrosis factor receptors in response to bacterial lipopolysaccharide

1989 • 131 citations

Reduced tumour necrosis factor-induced cytotoxicity by inhibitors of the arachidonic acid metabolism

1987 • 121 citations

Δ12-prostaglandin J2, an ultimate metabolite of prostaglandin D2 exerting cell growth inhibition

1985 • 103 citations

Modulation of endogenous hormone action by recombinant human tumor necrosis factor.

1987 • 103 citations

Immunohistochemical demonstration of cytoplasmic and membrane-associated tumor necrosis factor in murine macrophages.

1988 • 101 citations

Macrophage-mediated cytotoxicity: role of a soluble macrophage cytotoxic factor similar to lymphotoxin and tumor necrosis factor.

1983 • 99 citations

Tumor necrosis factor stimulates DNA synthesis in the liver of intact rats

1988 • 92 citations

Differential inhibition of prostaglandin and superoxide production by dexamethasone in primary cultures of rat Kupffer cells

1986 • 90 citations

Involvement of Prostaglandin E and Adenosine 3′ 5′‐Monophosphate in Lipopolysaccharide‐Stimulated Collagenase Release by Rat Kupffer Cells

1982 • 89 citations

Overlapping polypeptide induction in human fibroblasts in response to treatment with interferon-alpha, interferon-gamma, interleukin 1 alpha, interleukin 1 beta, and tumor necrosis factor.

1988 • 84 citations

Evidence for two mechanisms by which tumor necrosis factor kills cells

1989 • 80 citations

Glycogenolytic and haemodynamic responses to heat-aggregated immunoglobulin G and prostaglandin E2 in the perfused rat liver

1987 • 69 citations

Plasma membrane-associated tumor necrosis factor. A non-integral membrane protein possibly bound to its own receptor.

1988 • 69 citations

Augmentation of antitumor efficacy by the combination of recombinant tumor necrosis factor and chemotherapeutic agents in vivo.

1989 • 67 citations

Tumor necrosis factor induces synthesis of two proteins in human fibroblasts.

1986 • 65 citations

Ca2+ requirement of prostanoid but not of superoxide production by rat Kupffer cells

1988 • 53 citations

Molecular events in the activation of murine macrophages

1989 • 49 citations

The effect of kupffer cell stimulation or depression on the development of liver metastases in the rat

1986 • 46 citations

Tumor necrosis factor/cachectin and related cytokines

1989 • 39 citations

Tumor Necrosis Factor-Induced Downregulation of Its Receptors in HeLa Cells

1987 • 38 citations

Role of tumor necrosis factor and interleukin 1 in gamma-interferon-promoted activation of mouse tumoricidal macrophages.

1989 • 37 citations

Tumor necrosis factor/cachectin and related cytokines

1988 • 27 citations

Production and characterization of monoclonal antibodies against recombinant human tumor necrosis factor/cachectin

1986 • 25 citations

Output and Effects of Thromboxane Produced by the Liver Perfused with Phorbol Myristate Acetate

1988 • 20 citations

Ca²⁺ requirement of prostanoid but not of superoxide production by rat Kupffer cells

1988 • 10 citations

Regulation of interleukin 6 secretion by rat Kupffer cells

1989 • 2 citations