Aryl Hydrocarbon Hydroxylase Induction by Polycyclic Hydrocarbons: Simple Autosomal Dominant Trait in the Mouse

Pharmacological implications of microsomal enzyme induction.

1967 • 2,883 citations

The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase.

1968 • 1,767 citations

Substrate-inducible Microsomal Aryl Hydroxylase in Mammalian Cell Culture

1968 • 1,691 citations

Biology of the Laboratory Mouse

1967 • 1,382 citations

Biology of the Laboratory Mouse

1941 • 826 citations

Resolution of the Cytochrome P-450-containing ω-Hydroxylation System of Liver Microsomes into Three Components

1969 • 573 citations

The in vivo and in vitro induction of aryl hydrocarbon hydroxylase in mammalian cells of different species, tissues, strains, and developmental and hormonal states

1969 • 425 citations

Chloramphenicol in the Newborn Infant

1960 • 352 citations

Enzyme synthesis and degradation in mammalian systems

1971 • 310 citations

Substrate-inducible Microsomal Aryl Hydroxylase in Mammalian Cell Culture

1968 • 263 citations

Genetic Regulation of Aryl Hydrocarbon Hydroxylase Induction

1972 • 247 citations

Induction of drug metabolism. I. Differences in the mechanisms by which polycyclic hydrocarbons and phenobarbital produce their inductive effects on microsomal N-demethylating systems.

1969 • 218 citations

In Vitro Transformation of Rodent Cells by K-Region Derivatives of Polycyclic Hydrocarbons

1971 • 190 citations

An epoxide is an intermediate in the microsomal metabolism of the chemical carcinogen, dibenz(a,h)anthracene

1971 • 172 citations

Interactions of the k-region epoxides of phenanthrene and dibenz[a,h]anthracene with nucleic acids and histone

1970 • 115 citations

Induction of drug metabolism. II. Qualitative differences in the microsomal N-demethylating systems stimulated by polycyclic hydrocarbons and by phenobarbital.

1969 • 111 citations

Aryl Hydrocarbon Hydroxylase Induction in Mammalian Liver Cell Culture

1971 • 108 citations

Genetic Aspects of Increase in Rat Liver Aldehyde Dehydrogenase Induced by Phenobarbital

1971 • 105 citations

The Role of Ribonucleic Acid and Protein Synthesis in Microsomal Aryl Hydrocarbon Hydroxylase Induction in Cell Culture

1970 • 95 citations

Purification and Properties of δ-Aminolevulinate Dehydratase from Tissues of Two Strains of Mice

1966 • 76 citations

Genetic regulation of enzyme activity in mammalian system by the alteration of the rates of enzyme degradation

1967 • 68 citations

Aryl Hydrocarbon Hydroxylase Induction in Mammalian Liver Cell Culture

1971 • 66 citations

Further studies on the relationship of the stimulatory effects of phenobarbital and 3,4-benzpyrene on hepatic heme synthesis to their effects on hepatic microsomal drug oxidations

1970 • 65 citations

Microsomal Hydroxylase Induction in Liver Cell Culture by Phenobarbital, Polycyclic Hydrocarbons, and p , p ′-DDT

1971 • 56 citations

Factors that affect the stimulation of the microsomal drug enzymes induced by foreign compounds

1963 • 55 citations

THE GENETIC CONTROL OF THREE KIDNEY ESTERASES IN C57BL/6J AND RF/J MICE

1965 • 54 citations

Inheritance of Low Liver Glucuronidase Activity in the Mouse

1952 • 52 citations

Microsomal Cytochromes b5 and P450 during Induction of Aryl Hydrocarbon Hydroxylase Activity in Mammalian Cell Culture

1970 • 45 citations

Studies of a Mutation Affecting Pyrimidine Degradation in Inbred Mice

1970 • 42 citations

ARYL HYDROCARBON HYDROXYLASE INDUCTION IN CELL CULTURE AS A FUNCTION OF GENE EXPRESSION GENE EXPRESSION

1971 • 40 citations

Benzpyrene hydroxylase activity and its induction by methylcholanthrene in Morris hepatomas, in host livers, in adult livers, and in rat liver during development.

1970 • 33 citations

Induction of Hepatic δ-Aminolevulinic Acid Synthetase Activity in Strains of Inbred Mice

1971 • 30 citations

Fate of inducer during induction of aryl hydrocarbon hydroxylase activity in mammalian cell culture. I. Intracellular entry, binding, distribution, and metabolism.

1970 • 28 citations

Induction of Microsomal Oxidase in F ₁ Hybrids of a High and a Low Oxidase Housefly Strain

1971 • 27 citations

Fate of inducer during induction of aryl hydrocarbon hydroxylase activity in mammalian cell culture. II. Levels of intracellular polycyclic hydrocarbon during enzyme induction and decay.

1970 • 26 citations

Gene Expression: Its Specificity and Regulation

1962 • 25 citations