Microsomal Hydroxylase Induction in Liver Cell Culture by Phenobarbital, Polycyclic Hydrocarbons, and p , p ′-DDT

Pharmacological implications of microsomal enzyme induction.

1967 • 2,883 citations

Substrate-inducible Microsomal Aryl Hydroxylase in Mammalian Cell Culture

1968 • 1,691 citations

The in vivo and in vitro induction of aryl hydrocarbon hydroxylase in mammalian cells of different species, tissues, strains, and developmental and hormonal states

1969 • 425 citations

Substrate-inducible Microsomal Aryl Hydroxylase in Mammalian Cell Culture

1968 • 263 citations

Induction of drug metabolism. I. Differences in the mechanisms by which polycyclic hydrocarbons and phenobarbital produce their inductive effects on microsomal N-demethylating systems.

1969 • 218 citations

ADVANCES IN ENZYMOLOGY AND RELATED SUBJECTS OF BIOCHEMISTRY

1966 • 149 citations

Induction of drug metabolism. II. Qualitative differences in the microsomal N-demethylating systems stimulated by polycyclic hydrocarbons and by phenobarbital.

1969 • 111 citations

Aryl Hydrocarbon Hydroxylase Induction in Mammalian Liver Cell Culture

1971 • 108 citations

Genetic Differences in the Extent of Aryl Hydrocarbon Hydroxylase Induction in Mouse Fetal Cell Cultures

1970 • 96 citations

The Role of Ribonucleic Acid and Protein Synthesis in Microsomal Aryl Hydrocarbon Hydroxylase Induction in Cell Culture

1970 • 95 citations

Aryl Hydrocarbon Hydroxylase Induction in Mammalian Liver Cell Culture

1971 • 66 citations

Further studies on the relationship of the stimulatory effects of phenobarbital and 3,4-benzpyrene on hepatic heme synthesis to their effects on hepatic microsomal drug oxidations

1970 • 65 citations

Factors that affect the stimulation of the microsomal drug enzymes induced by foreign compounds

1963 • 55 citations

Benzpyrene Hydroxylase Induction by Polycyclic Hydrocarbons in Hamster Embryonic Cells Grown in vitro

1967 • 48 citations

Microsomal Cytochromes b5 and P450 during Induction of Aryl Hydrocarbon Hydroxylase Activity in Mammalian Cell Culture

1970 • 45 citations

ARYL HYDROCARBON HYDROXYLASE INDUCTION IN CELL CULTURE AS A FUNCTION OF GENE EXPRESSION GENE EXPRESSION

1971 • 40 citations

Fate of inducer during induction of aryl hydrocarbon hydroxylase activity in mammalian cell culture. I. Intracellular entry, binding, distribution, and metabolism.

1970 • 28 citations

Fate of inducer during induction of aryl hydrocarbon hydroxylase activity in mammalian cell culture. II. Levels of intracellular polycyclic hydrocarbon during enzyme induction and decay.

1970 • 26 citations

Changes in aryl hydrocarbon hydroxylase activity and microsomal P450 during polycyclic hydrocarbon treatment of mammalian cells in culture

1969 • 16 citations