A copper(II)-selective chelator ameliorates diabetes-evoked renal fibrosis and albuminuria, and suppresses pathogenic TGF-β activation in the kidneys of rats used as a model of diabetes

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A simplified method for the analysis of hydroxyproline in biological tissues

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Glucose-Induced Reactive Oxygen Species Cause Apoptosis of Podocytes and Podocyte Depletion at the Onset of Diabetic Nephropathy

2006 • 1,030 citations

Proteinuria, a target for renoprotection in patients with type 2 diabetic nephropathy: Lessons from RENAAL

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Identification of N epsilon-carboxymethyllysine as a degradation product of fructoselysine in glycated protein.

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TGF-β: Regulation of extracellular matrix

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SPARC is a source of copper-binding peptides that stimulate angiogenesis.

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Streptozotocin Interactions with Pancreatic β Cells and the Induction of Insulin-Dependent Diabetes

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Transition Metals Bind to Glycated Proteins Forming Redox Active “Glycochelates”: Implications for the Pathogenesis of Certain Diabetic Complications

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Circulating semicarbazide-sensitive amine oxidase is raised both in Type I (insulin-dependent), in Type II (non-insulin-dependent) diabetes mellitus and even in childhood Type I diabetes at first clinical diagnosis

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Transforming growth factor-beta and the glomerular extracellular matrix in renal pathology.

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Demonstration of a Hyperglycemia-Driven Pathogenic Abnormality of Copper Homeostasis in Diabetes and Its Reversibility by Selective Chelation

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Collagen accumulation is decreased in SPARC-null mice with bleomycin-induced pulmonary fibrosis

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Tetrathiomolybdate therapy protects against bleomycin-induced pulmonary fibrosis in mice

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Comparisons of tissue-specific transcription of stress response genes with whole animal endpoints of adverse effect in striped bass (Morone saxatilis) following treatment with copper and esfenvalerate

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Plasminogen activator inhibitor‐1 and diabetic nephropathy

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The renal expression of heat shock protein 47 and collagens in acute and chronic experimental diabetes in rats.

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Copper–metallothionein in the Kidney of Macular Mice: A Model for Menkes Disease

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Semicarbazide-sensitive amine oxidase in aortic smooth muscle cells mediates synthesis of a methylglyoxal-AGE: implications for vascular complications in diabetes

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Tetrathiomolybdate Protects against Bile Duct Ligation-Induced Cholestatic Liver Injury and Fibrosis

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Molecular Changes Evoked by Triethylenetetramine Treatment in the Extracellular Matrix of the Heart and Aorta in Diabetic Rats

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Semicarbazide-Sensitive Amine Oxidase and Extracellular Matrix Deposition by Smooth-Muscle Cells

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Endothelin‐1–Mediated Alteration of Metallothionein and Trace Metals in the Liver and Kidneys of Chronically Diabetic Rats

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Tetrathiomolybdate Therapy Protects Against Concanavalin a and Carbon Tetrachloride Hepatic Damage in Mice

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New Potential Agents in Treating Diabetic Kidney Disease

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Characterization of Dicarboxylic Salts of Protonated Triethylenetetramine Useful for the Treatment of Copper-Related Pathologies

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Histochemical and immunohistochemical localization of copper, iron and metallothionein in the liver and kidney of LEC rats.

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Abnormal Accumulation of Copper-Metallothionein in the Liver and Kidney of Long-Evans Rats with a Cinnamon-Like Coat Color (LEC Rats).

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Inhibitory Effects of Trientine, a Copper-Chelating Agent, on Induction of DNA Strand Breaks in Kidney Cells of Long-Evans Cinnamon (LEC) Rats

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Accumulation of copper in kidney of spontaneously hypertensive rats, a preliminary study

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