Regeneration of the Heart in Diabetes by Selective Copper Chelation

Free radicals in biology and medicine

1991 • 17,840 citations

The Metabolic and Molecular Bases of Inherited Disease

1995 • 12,086 citations

Biochemistry and molecular cell biology of diabetic complications

2001 • 8,707 citations

Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol

2002 • 5,471 citations

[1] Role of free radicals and catalytic metal ions in human disease: An overview

1990 • 5,041 citations

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

2000 • 4,169 citations

A novel MHC class I–like gene is mutated in patients with hereditary haemochromatosis

1996 • 3,682 citations

New type of cardiomyopathy associated with diabetic glomerulosclerosis

1972 • 1,725 citations

Cardiovascular morbidity and mortality in patients with diabetes in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol

2002 • 1,592 citations

Undetectable Intracellular Free Copper: The Requirement of a Copper Chaperone for Superoxide Dismutase

1999 • 1,573 citations

The Wilson disease gene is a copper transporting ATPase with homology to the Menkes disease gene

1993 • 1,345 citations

The biological chemistry of the elements: the inorganic chemistry of life

1992 • 1,298 citations

Lipotoxic heart disease in obese rats: Implications for human obesity

2000 • 1,257 citations

The Biological Chemistry of the Elements

2001 • 926 citations

Protein glycation and oxidative stress in diabetes mellitus and ageing

1991 • 882 citations

Identification of N epsilon-carboxymethyllysine as a degradation product of fructoselysine in glycated protein.

1986 • 830 citations

Losartan-Dependent Regression of Myocardial Fibrosis Is Associated With Reduction of Left Ventricular Chamber Stiffness in Hypertensive Patients

2002 • 616 citations

Function, Structure, and Mechanism of Intracellular Copper Trafficking Proteins

2001 • 489 citations

Iron in the heart

1971 • 478 citations

A Breaker of Advanced Glycation End Products Attenuates Diabetes-Induced Myocardial Structural Changes

2003 • 436 citations

The effect of diabetes on performance and metabolism of rat hearts.

1980 • 255 citations

Hepatic iron concentration combined with long‐term monitoring of serum ferritin to predict complications of iron overload in thalassaemia major

2000 • 237 citations

Subclinical States of Glucose Intolerance and Risk of Death in the U.S.

2001 • 236 citations

Mutations in SCO2 are associated with a distinct form of hypertrophic cardiomyopathy and cytochrome c oxidase deficiency

2000 • 223 citations

Left Ventricular Mass and Volume: Fast Calculation with Guide-Point Modeling on MR Images

2000 • 202 citations

Streptozotocin-induced Changes in Cardiac Gene Expression in the Absence of Severe Contractile Dysfunction

2000 • 196 citations

Screening for and treating left-ventricular abnormalities in diabetes mellitus: a new way of reducing cardiac deaths

2002 • 149 citations

Neurovascular dysfunction in diabetic rats. Potential contribution of autoxidation and free radicals examined using transition metal chelating agents.

1995 • 145 citations

The possible role of copper ions in atherogenesis: the Blue Janus

1997 • 143 citations

Left Ventricular Hypertrophy in Ascending Aortic Stenosis Mice

2000 • 127 citations

Transition Metals Bind to Glycated Proteins Forming Redox Active “Glycochelates”: Implications for the Pathogenesis of Certain Diabetic Complications

1998 • 127 citations

Copper chelation represses the vascular response to injury

2003 • 123 citations

A Functional and Ultrastructural Analysis of Experimental Diabetic Rat Myocardium: Manifestation of a Cardiomyopathy

1985 • 90 citations

Physiological and metabolic characterization of a cardiomyopathy induced by chronic copper deficiency

1983 • 89 citations

Long-term treatment of Wilson's disease with triethylene tetramine dihydrochloride (trientine)

1995 • 81 citations

Disorder of copper transport

2001 • 58 citations

Transition metals redox: reviving an old plot for diabetic vascular disease

2001 • 54 citations

Inhibition of Nitric Oxide Synthase byL-NAME Improves Ventricular Performance in Streptozotocin- diabetic Rats

1997 • 50 citations

Cardiovascular effects of dietary copper deficiency

1999 • 49 citations

Mode of action of triethylenetetramine dihydrochloride on copper metabolism in Wilson's disease

1991 • 46 citations

An automated method for the determination of Cu,Zn-superoxide dismutase in plasma and erythrocytes using an ABA-200™ discrete analyzer

1986 • 46 citations

Reduced contraction strength with increased intracellular [Ca²⁺] in left ventricular trabeculae from failing rat hearts

2003 • 44 citations

Experimental diabetes and left ventricular hypertrophy

2002 • 39 citations

A functional and ultrastructural analysis of experimental diabetic rat myocardium. Manifestation of a cardiomyopathy

1985 • 38 citations

Integrin shedding as a mechanism of cellular adaptation during cardiac growth

2003 • 38 citations

Non‐invasive magnetic resonance imaging assessment of myocardial changes and the effects of angiotensin‐converting enzyme inhibition in diabetic rats

2002 • 35 citations

CHANGES IN DIASTOLIC FUNCTION AND COLLAGEN CONTENT IN NORMOTENSIVE AND HYPERTENSIVE RATS WITH LONG-TERM STREPTOZOTOCIN-INDUCED DIABETES

1998 • 34 citations

Electron spin resonance studies of copper(II) polyamine and imidazole complexes

1986 • 34 citations

Contrasting and Cooperative Effects of Copper and Iron Deficiencies in Male Rats Fed Different Concentrations of Manganese and Different Sources of Sulfur Amino Acids in an AIN-93G-Based Diet

2004 • 33 citations

[Changes in diameter size and F-actin expression in the myocytes of patients with diabetes and streptozotocin-induced diabetes model rats].

1999 • 16 citations