Priming or Tolerization of the B- and Th2-Dependent Immune Response by the Oral Administration of OVA-DNP Is Determined by the Antigen Dosage

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1983 • 52,849 citations

Rapid colorimetric assay for cell growth and survival

1986 • 4,672 citations

Regulatory T Cell Clones Induced by Oral Tolerance: Suppression of Autoimmune Encephalomyelitis

1994 • 1,995 citations

Methods in Immunology and Immunochemistry

1967 • 1,145 citations

Peripheral deletion of antigen-reactive T cells in oral tolerance

1995 • 775 citations

Induction of anergy or active suppression following oral tolerance is determined by antigen dosage.

1994 • 643 citations

Immunodetection and quantitation of the two forms of transforming growth factor‐beta (TGF‐β1 and TGF‐β2) secreted by cells in culture

1989 • 453 citations

Antigens of activated rat T lymphocytes including a molecule of 50,000 Mr detected only on CD4 positive T blasts

1987 • 453 citations

Oral tolerance in experimental autoimmune encephalomyelitis. III. Evidence for clonal anergy.

1991 • 450 citations

Cholera toxin B subunit: an efficient transmucosal carrier-delivery system for induction of peripheral immunological tolerance.

1994 • 317 citations

Identification of a human OX-40 ligand, a costimulator of CD4+ T cells with homology to tumor necrosis factor.

1994 • 271 citations

Direct evidence for anergy in T lymphocytes tolerized by oral administration of ovalbumin

1993 • 233 citations

Induction of oral tolerance to myelin basic protein in CD8-depleted mice: both CD4+ and CD8+ cells mediate active suppression.

1995 • 222 citations

Enterically induced immunologic tolerance. I. Induction of suppressor T lymphoyctes by intragastric administration of soluble proteins.

1978 • 218 citations

T helper 2 cells are subject to high dose oral tolerance and are not essential for its induction.

1995 • 171 citations

Aqueous antigens induce in vivo tolerance selectively in IL-2- and IFN-gamma-producing (Th1) cells.

1992 • 163 citations

Oral Tolerance to Myelin Basic Protein Induces Regulatory TGF-β-Secreting T Cells in Peyer's Patches of SJL Mice

1994 • 151 citations

In vivo role of interleukin 4 in T cell tolerance induced by aqueous protein antigen.

1993 • 140 citations

Inhibition of Specific Immune Responses by Feeding Protein Antigens

1977 • 126 citations

Enterically Induced Immunologic Tolerance

1978 • 117 citations

In vivo tolerization of Th1 lymphocytes following a single feeding with ovalbumin: Anergy in the absence of suppression

1994 • 113 citations

Anti-CD3 antibody induces unresponsiveness to IL-2 in Th1 clones but not in Th2 clones.

1990 • 109 citations

Oral antigen inhibits priming of CD8+ CTL, CD4+ T cells, and antibody responses while activating CD8+ suppressor T cells.

1996 • 101 citations

Peripheral tolerance of T_h2 lymphocytes induced by continuous feeding of ovalbumin

1996 • 80 citations

Breaking of B cell tolerance toward a highly conserved self protein.

1996 • 75 citations

Mucosal tolerance is associated with, but independent of, up‐regulation Th2 responses

1997 • 50 citations

Conversion of orally induced suppression of the mucosal immune response to ovalbumin into stimulation by conjugating ovalbumin to cholera toxin or its B subunit

1994 • 39 citations

Selective suppression of antigen-specific Th2 cells by continuous micro-dose oral tolerance

1998 • 25 citations

Differential inhibition of T and B cell responses to individual antigenic determinants in orally tolerized mice

1994 • 18 citations

Evidence for Th2 cell‐mediated suppression of antibody responses in transgenic, beef insulin‐tolerant mice

1995 • 17 citations

The bone marrow as a site of antibody production after a mucosal immunization

1995 • 9 citations