Conversion of orally induced suppression of the mucosal immune response to ovalbumin into stimulation by conjugating ovalbumin to cholera toxin or its B subunit

The regulation of immune responses to dietary protein antigens

1987 • 489 citations

Generalized systemic and mucosal immunity in mice after mucosal stimulation with cholera toxin.

1984 • 445 citations

Systemic tolerance and secretory immunity after oral immunization.

1980 • 432 citations

Strong adjuvant properties of cholera toxin on gut mucosal immune responses to orally presented antigens.

1986 • 428 citations

Identification ofEscherichia coli heat-labile enterotoxin by means of a ganglioside immunosorbent assay (GM1-ELISA) procedure

1978 • 359 citations

Cellular kinetics of the intestinal immune response to cholera toxoid in rats.

1975 • 353 citations

Cholera toxin feeding did not induce oral tolerance in mice and abrogated oral tolerance to an unrelated protein antigen.

1984 • 334 citations

Enterically induced immunologic tolerance. I. Induction of suppressor T lymphoyctes by intragastric administration of soluble proteins.

1978 • 218 citations

Oral vaccination. Identification of classes of proteins that provoke an immune response upon oral feeding.

1988 • 211 citations

Cholera toxin B subunit as a carrier protein to stimulate a mucosal immune response.

1984 • 196 citations

Absorption of antigens after oral immunisation and the simultaneous induction of specific systemic tolerance.

1979 • 169 citations

Oral administration of cholera toxin-Sendai virus conjugate potentiates gut and respiratory immunity against Sendai virus.

1988 • 133 citations

Improved procedure for the isolation of functionally active lymphoid cells from the murine intestine

1987 • 113 citations

The Adjuvant Action of Cholera Toxin is Associated with an Increased Intestinal Permeability for Luminal Antigens

1991 • 111 citations

Special features of the priming process for a secretory IgA response. B cell priming with cholera toxin.

1981 • 97 citations

Oral tolerance to ovalbumin in mice: studies of chemically modified and 'biologically filtered' antigen.

1986 • 90 citations

A selected water-in-oil emulsion: Composition and usefulness as an immunological adjuvant

1981 • 89 citations

Receptor‐Specific Large‐Scale Purification of Cholera Toxin on Silica Beads Derivatized with LysoG_M1 Ganglioside

1981 • 80 citations

Priming of systemic and local delayed-type hypersensitivity responses by feeding low doses of ovalbumin to mice.

1989 • 62 citations

Adjuvant action of cholera toxin and pertussis toxin in the induction of IgA antibody response to orally administered antigen

1993 • 54 citations

SALIVARY ANTIBODIES AND SYSTEMIC TOLERANCE IN MICE AFTER ORAL IMMUNIZATION WITH BACTERIAL ANTIGENS*

1983 • 53 citations

The role of antigen recognition and suppressor cells in mice with oral tolerance to ovalbumin.

1985 • 53 citations

Manipulation of intestinal immune responses against ovalbumin by cholera toxin and its B subunit in mice.

1991 • 52 citations

Cholera toxin as a mucosal adjuvant. Glutaraldehyde treatment dissociates adjuvanticity from toxicity.

1989 • 38 citations

Expression in Escherichia coli of two mutated genes encoding the cholera toxin B subunit

1990 • 35 citations

The use of monoclonal antibodies in an enzyme immunospot assay to detect isotype-specific antibody-secreting cells in pigs and chickens

1990 • 22 citations

Quantification of antigen-specific antibody-secreting cells in the small intestine and other lymphoid organs of mice after oral booster immunization.

1989 • 17 citations

Induction of an enteric Ig-response against ovalbumin and stimulation of the response by cholera toxin and its B-subunit in mice.

1990 • 7 citations