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Mucosal tolerance is associated with, but independent of, up‐regulation Th2 responses

Data up to Jan 2025

Published1997
Citations50
References26

Total Citations Per Year

Abstract

References (26)

The expanding universe of T-cell subsets: Th1, Th2 and more

1996 • 3,710 citations

Regulatory T Cell Clones Induced by Oral Tolerance: Suppression of Autoimmune Encephalomyelitis

1994 • 1,995 citations

B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy

1995 • 1,695 citations

Lymphokine Control of In Vivo Immunoglobulin Isotype Selection

1990 • 1,303 citations

Generation and Analysis of Interleukin-4 Deficient Mice

1991 • 1,266 citations

Peripheral deletion of antigen-reactive T cells in oral tolerance

1995 • 775 citations

Production of a monoclonal antibody to and molecular characterization of B-cell stimulatory factor-1

1985 • 749 citations

Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor beta after antigen-specific triggering.

1992 • 734 citations

Induction of anergy or active suppression following oral tolerance is determined by antigen dosage.

1994 • 643 citations

Oral tolerance in experimental autoimmune encephalomyelitis. III. Evidence for clonal anergy.

1991 • 450 citations

Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes.

1996 • 428 citations

Regulation of IgE Responses to Inhaled Antigen in Mice by Antigen-Specific γδ T Cells

1994 • 406 citations

IL-4 induces a Th2 response in Leishmania major-infected mice.

1992 • 403 citations

Patterns of lymphatic drainage in the adult laboratory rat.

1971 • 397 citations

Strategies of Anti‐Cytokine Monoclonal Antibody Development: Immunoassay of IL‐10 and IL‐5 in Clinical Samples

1992 • 384 citations

Dendritic cells can present antigen in vivo in a tolerogenic or immunogenic fashion.

1996 • 330 citations

Suppression of experimental autoimmune encephalomyelitis by oral administration of myelin basic protein. II. Suppression of disease and in vitro immune responses is mediated by antigen-specific CD8+ T lymphocytes.

1989 • 284 citations

Direct evidence for anergy in T lymphocytes tolerized by oral administration of ovalbumin

1993 • 233 citations

T helper 2 cells are subject to high dose oral tolerance and are not essential for its induction.

1995 • 171 citations

The injured cell: the role of the dendritic cell system as a sentinel receptor pathway

1995 • 154 citations

Similar frequencies and kinetics of cytokine producing cells in murine peripheral blood and spleen

1993 • 147 citations

Regulation of house dust mite responses by intranasally administered peptide: transient activation of CD4+ T cells precedes the development of tolerance in vivo

1996 • 137 citations

IgE and mast cell responses on intestinal allergen exposure: A murine model to study the onset of food allergy

1997 • 80 citations

alpha beta T cell receptor-positive intraepithelial lymphocytes with CD4+, CD8- and CD4+, CD8+ phenotypes from orally immunized mice provide Th2-like function for B cell responses.

1993 • 55 citations

Regulation of T-cell sensitization at epithelial surfaces in the respiratory tract: suppression of IgE responses to inhaled antigens by CD3+ Tcr alpha-/beta- lymphocytes (putative gamma/delta T cells).

1991 • 52 citations

Anti‐IL‐10 Treatment Does Not Block Either the Induction or the Maintenance of Orally Induced Tolerance to Ova

1995 • 44 citations

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Mucosal tolerance is associated with, but independent of, up‐regulation Th2 responses (1997) – Immunology | Metascience Observatory Explorer