A cholesterol-regulated PP2A/HePTP complex with dual specificity ERK1/2 phosphatase activity

The SREBP Pathway: Regulation of Cholesterol Metabolism by Proteolysis of a Membrane-Bound Transcription Factor

1997 • 3,702 citations

Regulation of Renal Organic Anion Transporter 3 (SLC22A8) Expression and Function by the Integrity of Lipid Raft Domains and their Associated Cytoskeleton

2013 • 2,950 citations

Caveolin, a protein component of caveolae membrane coats

1992 • 2,230 citations

THE CAVEOLAE MEMBRANE SYSTEM

1998 • 1,947 citations

Crucial Step in Cholesterol Homeostasis

2002 • 945 citations

VIP21/caveolin is a cholesterol-binding protein.

1995 • 892 citations

MAP kinase pathways

1999 • 875 citations

A conserved docking motif in MAP kinases common to substrates, activators and regulators

2000 • 801 citations

Dual specificity phosphatases: a gene family for control of MAP kinase function

2000 • 791 citations

A detergent-free method for purifying caveolae membrane from tissue culture cells.

1995 • 732 citations

Atomic structure of the MAP kinase ERK2 at 2.3 Å resolution

1994 • 591 citations

The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation

1993 • 521 citations

A Role for Caveolin in Transport of Cholesterol from Endoplasmic Reticulum to Plasma Membrane

1996 • 496 citations

Catalytic Activation of the Phosphatase MKP-3 by ERK2 Mitogen-Activated Protein Kinase

1998 • 496 citations

Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase.

1996 • 414 citations

START: a lipid-binding domain in StAR, HD-ZIP and signalling proteins

1999 • 398 citations

Cholesterol Depletion of Caveolae Causes Hyperactivation of Extracellular Signal-related Kinase (ERK)

1998 • 375 citations

Localization of the insulin receptor in caveolae of adipocyte plasma membrane

1999 • 364 citations

Inactivation of p42 MAP kinase by protein phosphatase 2A and a protein tyrosine phosphatase, but not CL100, in various cell lines

1995 • 363 citations

Cholesterol depletion disrupts lipid rafts and modulates the activity of multiple signaling pathways in T lymphocytes

2000 • 338 citations

Protein phosphatase 2A: the Trojan Horse of cellular signaling

2001 • 334 citations

PTP-SL and STEP protein tyrosine phosphatases regulate the activation of the extracellular signal-regulated kinases ERK1 and ERK2 by association through a kinase interaction motif

1998 • 313 citations

Intracellular cholesterol transport

2002 • 301 citations

Intracellular cholesterol transport

1997 • 295 citations

Crosstalk between cAMP-dependent kinase and MAP kinase through a protein tyrosine phosphatase

1999 • 204 citations

The Specificity of Extracellular Signal-regulated Kinase 2 Dephosphorylation by Protein Phosphatases

2002 • 203 citations

Palmitoylation of Caveolin-1 Is Required for Cholesterol Binding, Chaperone Complex Formation, and Rapid Transport of Cholesterol to Caveolae

2000 • 176 citations

Progesterone blocks cholesterol translocation from lysosomes.

1992 • 170 citations

Cholesterol Oxidation Switches the Internalization Pathway of Endothelin Receptor Type A from Caveolae to Clathrin-coated Pits in Chinese Hamster Ovary Cells

2000 • 159 citations

MAP Kinases Erk1/2 Phosphorylate Sterol Regulatory Element-binding Protein (SREBP)-1a at Serine 117 in Vitro

2000 • 155 citations

Cholesteryl Ester Is Transported from Caveolae to Internal Membranes as Part of a Caveolin-Annexin II Lipid-Protein Complex

2002 • 117 citations

Localization of the murine Niemann-Pick C1 protein to two distinct intracellular compartments

2000 • 110 citations

Cloning and expression of an inducible lymphoid‐specific, protein tyrosine phosphatase (HePTPase)

1992 • 102 citations

Site-specific Phosphorylation of Tau Accompanied by Activation of Mitogen-activated Protein Kinase (MAPK) in Brains of Niemann-Pick Type C Mice

2001 • 97 citations

The Niemann-Pick C Proteins and Trafficking of Cholesterol Through the Late Endosomal / Lysosomal System

2002 • 86 citations

Niemann-Pick C1 protein regulates cholesterol transport to the trans-Golgi network and plasma membrane caveolae

2002 • 79 citations

Cholesterol movement from plasma membrane to rough endoplasmic reticulum. Inhibition by progesterone.

1994 • 78 citations

Apolipoprotein A-I Induces Translocation of Cholesterol, Phospholipid, and Caveolin-1 to Cytosol in Rat Astrocytes

2002 • 70 citations

Hematopoietic Protein Tyrosine Phosphatase Suppresses Extracellular Stimulus-Regulated Kinase Activation

2001 • 66 citations

Presence of Oxidized Cholesterol in Caveolae Uncouples Active Platelet-derived Growth Factor Receptors from Tyrosine Kinase Substrates

2000 • 48 citations

Cloning and expression of PCPTP1 encoding protein tyrosine phosphatase

1995 • 47 citations

The MAP-kinase ERK2 is a specific substrate of the protein tyrosine phosphatase HePTP

2000 • 43 citations

The Npc1 mutation causes an altered expression of caveolin-1, annexin II and protein kinases and phosphorylation of caveolin-1 and annexin II in murine livers

1999 • 38 citations