Immunoreactive proinsulin-like growth factor-II levels in healthy subjects, patients with growth hormone deficiency, and patients with type 1 diabetes: effects of insulin-like growth factor-I and insulin.

Antibodies, a laboratory manual

1989 • 12,929 citations

Solid Phase Peptide Synthesis. I. The Synthesis of a Tetrapeptide

1963 • 7,266 citations

Enzyme-linked immunosorbent assay, Elisa. 3. Quantitation of specific antibodies by enzyme-labeled anti-immunoglobulin in antigen-coated tubes.

1972 • 3,187 citations

Effect of insulin on the hepatic production of insulin-like growth factor-binding protein-1 (IGFBP-1), IGFBP-3, and IGF-I in insulin-dependent diabetes.

1994 • 328 citations

Sequence of a cDNA clone encoding human preproinsulin-like growth factor II

1984 • 326 citations

Insulin-like growth factor II precursor gene organization in relation to insulin gene family

1984 • 281 citations

Insulin-like growth factor II acts as an autocrine growth and motility factor in human rhabdomyosarcoma tumors.

1990 • 242 citations

Insulin-like growth factor II in human adrenal pheochromocytomas and Wilms tumors: expression at the mRNA and protein level.

1987 • 191 citations

EVIDENCE FOR TWO SPECIES OF INSULIN-LIKE GROWTH FACTOR II (IGF II AND “BIG” IGF II) IN HUMAN SPINAL FLUID

1982 • 158 citations

The gene structure of the insulin-like growth factor family

1989 • 143 citations

IGF-2 stimulated growth mediated by the somatomedin type 2 receptor

1987 • 121 citations

Amino acid sequence of a variant pro-form of insulin-like growth factor II.

1985 • 106 citations

Serum "big insulin-like growth factor II" from patients with tumor hypoglycemia lacks normal E-domain O-linked glycosylation, a possible determinant of normal propeptide processing.

1993 • 99 citations

Identification and initial characterization of a fourth leader exon and promoter of the human IGF-II gene

1990 • 91 citations

Relative abundance and molecular size of immunoreactive insulin-like growth factors I and II in human fetal tissues

1990 • 61 citations

Measurement of derivatives of proinsulin-like growth factor-II in serum by a radioimmunoassay directed against the E-domain in normal subjects and patients with nonislet cell tumor hypoglycemia.

1992 • 52 citations

The identification of O-glycosylated precursors of insulin-like growth factor II.

1992 • 44 citations

Growth hormone insensitivity syndromes: a preliminary report on changes in insulin-like growth factors and their binding proteins during treatment with recombinant insulin-like growth factor I

1993 • 30 citations

Abnormal processing of pro-IGF-II in patients with hepatoma and in some hepatitis B virus antibody-positive asymptomatic individuals.

1990 • 29 citations

Characterization of proinsulin-like growth factor-II E-region immunoreactivity in serum and other biological fluids.

1993 • 25 citations

Heterogeneity of serum peptides with immunoactivity detected by a radioimmunoassay for proinsulin-like growth factor-II E domain: description of a free E domain peptide in serum.

1992 • 25 citations

Effects of repeated subcutaneous administration of recombinant human insulin-like growth factor I in adults with growth hormone deficiency

1994 • 23 citations

Characterization of an extended form of recombinant human insulin-like growth factor II

1991 • 19 citations

Development of a Specific Radioimmuno Assay for E Domain Containing Forms of Insulin-Like Growth Factor II

1991 • 13 citations

Insulin‐Like Growth Factor II Effects Mediated through Insulin‐Like Growth Factor II Receptors

1990 • 9 citations