Genome-Wide Gene Expression Analysis for Induced Ischemic Tolerance and Delayed Neuronal Death following Transient Global Ischemia in Rats
Data up to Jan 2025
Total Citations Per Year
Abstract
References (76)
The rat brain in stereotaxic coordinates
1983 • 28,962 citations
Cluster analysis and display of genome-wide expression patterns
1998 • 16,410 citations
In silico prediction of protein-protein interactions in human macrophages
2014 • 11,120 citations
Significance analysis of microarrays applied to the ionizing radiation response
2001 • 10,393 citations
Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis
1995 • 5,334 citations
Delayed neuronal death in the gerbil hippocampus following ischemia
1982 • 2,856 citations
Expression monitoring by hybridization to high-density oligonucleotide arrays
1996 • 2,796 citations
Temporal profile of neuronal damage in a model of transient forebrain ischemia
1982 • 2,695 citations
Genomics, gene expression and DNA arrays
2000 • 2,039 citations
Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins
1998 • 1,335 citations
Gene-expression profile of the ageing brain in mice
2000 • 1,057 citations
Induction of Caspase-3-Like Protease May Mediate Delayed Neuronal Death in the Hippocampus after Transient Cerebral Ischemia
1998 • 706 citations
PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond
1997 • 699 citations
A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia
2003 • 656 citations
Cytochrome c Release and Apoptosis Induced by Mitochondrial Targeting of Nuclear Orphan Receptor TR3
2000 • 651 citations
NF-κB is activated and promotes cell death in focal cerebral ischemia
1999 • 648 citations
Effects of environmental enrichment on gene expression in the brain
2000 • 602 citations
Induced Tolerance to Ischemia in Gerbil Hippocampal Neurons
1991 • 584 citations
Ischemic Preconditioning and Brain Tolerance: Temporal Histological and Functional Outcomes, Protein Synthesis Requirement, and Interleukin-1 Receptor Antagonist and Early Gene Expression
1998 • 488 citations
Conditional Expression of the Mitogen-activated Protein Kinase (MAPK) Phosphatase MKP-1 Preferentially Inhibits p38 MAPK and Stress-activated Protein Kinase in U937 Cells
1997 • 435 citations
Reduced MAP Kinase Phosphatase-1 Degradation After p42/p44 MAPK -Dependent Phosphorylation
1999 • 414 citations
TGF-β induces apoptosis through Smad-mediated expression of DAP-kinase
2001 • 373 citations
Altered Patterns of Gene Expression in Response to Myocardial Infarction
2000 • 370 citations
Intravenous administration of MEK inhibitor U0126 affords brain protection against forebrain ischemia and focal cerebral ischemia
2001 • 364 citations
Role of Mitogen- and Stress-Activated Kinases in Ischemic Injury
2002 • 363 citations
The Dual Specificity Mitogen-activated Protein Kinase Phosphatase-1 and -2 Are Induced by the p42/p44MAPK Cascade
1997 • 358 citations
Requirement for nitric oxide activation of p21 ras /extracellular regulated kinase in neuronal ischemic preconditioning
2000 • 321 citations
Gene Expression Induced by Cerebral Ischemia: An Apoptotic Perspective
1997 • 305 citations
Ischemic Tolerance
2002 • 298 citations
Brain Genomic Response following Hypoxia and Re-oxygenation in the Neonatal Rat
2002 • 293 citations
Activation of Mitogen-Activated Protein Kinases after Transient Forebrain Ischemia in Gerbil Hippocampus
2000 • 252 citations
Expression of the Apoptosis‐Effector Gene, Bax, Is Up‐Regulated in Vulnerable Hippocampal CA1 Neurons Following Global Ischemia
1996 • 238 citations
Direct Comparison of GeneChip and SAGE on the Quantitative Accuracy in Transcript Profiling Analysis
2000 • 211 citations
How Protein Kinase C Activation Protects Nerve Cells from Oxidative Stress-Induced Cell Death
2001 • 211 citations
Expression profiling reveals distinct sets of genes altered during induction and regression of cardiac hypertrophy
2000 • 209 citations
Apoptosis Repressor Genes Bcl-2 and Bcl-x-Long are Expressed in the Rat Brain following Global Ischemia
1997 • 203 citations
Immediate-early gene protein expression in neurons undergoing delayed death, but not necrosis, following hypoxic-ischaemic injury to the young rat brain
1994 • 197 citations
Microarray analysis of hippocampal gene expression in global cerebral ischemia
2001 • 186 citations
Protein synthesis in the cat brain after prolonged cerebral ischemia
1971 • 184 citations
Blood genomic responses differ after stroke, seizures, hypoglycemia, and hypoxia: Blood genomic fingerprints of disease
2001 • 183 citations
The Mechanism of Dephosphorylation of Extracellular Signal-regulated Kinase 2 by Mitogen-activated Protein Kinase Phosphatase 3
2001 • 179 citations
Gene expression analysis of spontaneously hypertensive rat cerebral cortex following transient focal cerebral ischemia
2002 • 175 citations
Induction of c-Fos, junB, c-Jun, and hsp70 mRNA in Cortex, Thalamus, Basal Ganglia, and Hippocampus following Middle Cerebral Artery Occlusion
1994 • 150 citations
Akt Inhibits the Orphan Nuclear Receptor Nur77 and T-cell Apoptosis
2001 • 150 citations
GeneChip® analysis after acute spinal cord injury in rat
2001 • 148 citations
Early Growth Response-1 gene mediates up-regulation of epidermal growth factor receptor expression during hypoxia.
2002 • 139 citations
Expression deconvolution: A reinterpretation of DNA microarray data reveals dynamic changes in cell populations
2003 • 138 citations
Parallel Gene Expression Monitoring using Oligonucleotide Probe Arrays of Multiple Transcripts with an Animal Model of Focal Ischemia
2000 • 122 citations
Selective c‐JUN Expression in CA1 Neurons of the Gerbil Hippocampus during and after Acquisition of an Ischemia‐Tolerant State
1995 • 115 citations
Protective effect of spreading depression against neuronal damage following cardiac arrest cerebral ischaemia
1995 • 111 citations
Dral Is a P53-Responsive Gene Whose Four and a Half Lim Domain Protein Product Induces Apoptosis
2000 • 105 citations
Effect of ischemic preconditioning on the expression of putative neuroprotective genes in the rat brain
2002 • 86 citations
Use of Suppression Subtractive Hybridization for Differential Gene Expression in Stroke
2001 • 83 citations
Expression of Zinc Finger Immediate Early Genes in Rat Brain After Permanent Middle Cerebral Artery Occlusion
1997 • 82 citations
Global Ischemia Induces Immediate-Early Genes Encoding Zinc Finger Transcription Factors
1996 • 73 citations
Egr-1 inhibits apoptosis during the UV response: correlation of cell survival with Egr-1 phosphorylation
1998 • 68 citations
Gene Expression Profiling in Perilesional and Contralateral Areas after Ischemia in Rat Brain
2002 • 68 citations
Extracellular signal-regulated kinase and c-Jun N-terminal protein kinase in ischemic tolerance
2001 • 67 citations
Up‐regulation of gut‐enriched krüppel‐like factor by interferon‐γ in human colon carcinoma cells
2000 • 65 citations
Identification of differentially expressed genes induced by transient ischemic stroke
2002 • 57 citations
DNA array reveals altered gene expression in response to focal cerebral ischemia
2002 • 54 citations
Early c-Fos Induction after Cerebral Ischemia: A Possible Neuroprotective Role
2001 • 54 citations
Diphosphorylation of extracellular signal-regulated kinases and c-Jun N-terminal protein kinases in brain ischemic tolerance in rat
2000 • 53 citations
The Gene for Heparin-Binding Epidermal Growth Factor-Like Growth Factor is Stress-Inducible: Its Role in Cerebral Ischemia
1999 • 52 citations
RNF4 Is a Growth Inhibitor Expressed in Germ Cells but Not in Human Testicular Tumors
2001 • 49 citations
Early growth responsive‐1‐dependent manganese superoxide dismutase gene transcription mediated by platelet‐derived growth factor
2001 • 41 citations
Effect of Cortical Spreading Depression on the Levels of mRNA Coding for Putative Neuroprotective Proteins in Rat Brain
1998 • 40 citations
An enhanced expression of the immediate early gene, Egr-1, is associated with neuronal apoptosis in culture
1999 • 36 citations
Suppression of post-ischemic-induced Fos protein expression by an antisense oligonucleotide to c-fos mRNA leads to increased tissue damage
1999 • 34 citations
Effect of intra-ischemic hypothermia on the expression of c-Fos and c-Jun, and DNA binding activity of AP-1 after focal cerebral ischemia in rat brain
2003 • 33 citations
Inhibition of cytokine production and adhesion molecule expression by ibuprofen is without effect on transendothelial migration of monocytes.
1998 • 31 citations
Expression of the transcription factor GADD153 is an indicator of apoptosis for recombinant chinese hamster ovary (CHO) cells
2001 • 27 citations
Two caspase‐2 transcripts are expressed in rat hippocampus after global cerebral ischemia
2002 • 24 citations
Delayed induction of JunB precedes CA1 neuronal death after global ischemia in the gerbil
1999 • 19 citations
Biochemical changes and gene expression following traumatic brain injury: Role of spreading depression
1999 • 16 citations
Correlation between Delayed Neuronal Cell Death and Selective Decrease in Phosphatidylinositol 4-Kinase Expression in the CA1 Subfield of the Hippocampus after Transient Forebrain Ischemia
2003 • 14 citations